A5101423803- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer, Lipids, and Metabolism
- Thyroid Cancer Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Breast Cancer Treatment Studies
- Traditional Chinese Medicine Studies
- Medical Research and Treatments
- Nutrition and Health in Aging
- HER2/EGFR in Cancer Research
- Diet and metabolism studies
- Cancer Cells and Metastasis
- Pancreatic and Hepatic Oncology Research
- Inflammatory Biomarkers in Disease Prognosis
- Breast Lesions and Carcinomas
- Diet, Metabolism, and Disease
- Cancer, Hypoxia, and Metabolism
- Radiomics and Machine Learning in Medical Imaging
- Cancer Genomics and Diagnostics
- Head and Neck Anomalies
- Metabolism, Diabetes, and Cancer
- Lipid metabolism and disorders
- Esophageal and GI Pathology
- Cancer Risks and Factors
- Monoclonal and Polyclonal Antibodies Research
First Affiliated Hospital of Wenzhou Medical University
2013-2025
Wenzhou Medical University
2013-2025
Dalian Medical University
2024
Fuzhou University
2023
Zhengzhou University
2016-2019
Nanchang University
2019
Zhujiang Hospital
2016-2017
Angiologica (Italy)
2017
Southern Medical University
2016
YD Global Life Science (South Korea)
2015
The gut microbiota has been found to play an important role in the progression of metabolic dysfunction-associated steatohepatitis (MASH), but mechanisms have not established. Here, by developing a click-chemistry-based enrichment strategy, we identified several microbial-derived bile acids, including previously uncharacterized 3-succinylated cholic acid (3-sucCA), which is negatively correlated with liver damage patients liver-tissue-biopsy-proven fatty disease (MAFLD). By screening human...
Intake of n-3 polyunsaturated fatty acids (n-3 PUFAs) may protect against mild cognitive impairment (MCI). However, there is still a lack the PUFAs intervention in elderly with MCI China. The aim present study was to investigate effect PUFA supplementation on function Chinese MCI.Eighty six individuals aged 60 years or older were randomly assigned receive either (480 mg DHA and 720 EPA per day, n = 44) placebo (olive oil, 42) capsules. changes functions assessed using Basic Cognitive...
The impact of nutritional status on survival among elderly esophageal squamous cell carcinoma (ESCC) patients undergoing radiotherapy is unclear. In this study, we aimed at validating the performance geriatric risk index (GNRI) in predicting overall time ESCC with radiotherapy. A retrospective cohort study was conducted 239 aged 60 and over admitted consecutively from January 2008 to November 2014 Department Radiotherapy, Henan Tumor Hospital (Affiliated Zhengzhou University), Zhengzhou,...
// Jie You 1, 2, * , Gui-Qi Zhu 3, 4, Linka Xie 5, Wen-Yue Liu 6 Liang Shi 7 Ou-Chen Wang 1 Zong-Hai Huang 2 Martin Braddock 8 Gui-Long Guo Ming-Hua Zheng 9 Department of Oncological Surgery, The First Affiliated Hospital Wenzhou Medical University, 325000, China General Zhujiang Hospital, Southern Guangzhou 510282, 3 Infection and Liver Diseases, Research Center, 4 School Clinical Sciences, 5 Cancer Center Union Tongji College, Huazhong University Science Technology, Wuhan 430022,...
MicroRNA-27a (miR-27a) has been reported to be an onco-microRNA in multiple cancers promoting tumor growth and metastasis, but the role of miR-27a regulating cancer sensitivity chemotherapy remains unknown. In this study, upregulation was validated by real-time PCR analysis breast (BC) cell lines samples BC patients. A negative correlation between bak also observed normal epithelial line MCF-10A lines, suggesting that is potential target miR-27a. could modulate metastasis cells. More...
ABSTRACT Background Recent studies about human epidermal growth factor receptor 2 (HER2)‐low values have garnered great interest among oncologists. We aimed to investigate whether HER2‐low impacts the prognosis of early‐stage breast cancer overall and in specific subgroups, explore differences clinicopathologic markers, examine role age prognostic stratification. Materials & Methods conducted a retrospective analysis 6920 HER2‐negative patients from First Affiliated Hospital Wenzhou...
The interaction between the gut microbiome and cancer chemotherapy has been extensively studied. However, exact role of vaginal in remains unknown. To address this issue, we...
Epidemiological data suggests a close link between metabolic syndrome (MetS) and non-metastatic colorectal cancer (NMCRC). However, the relationship MetS outcome of NMCRC is less well understood. We aim to evaluate impact on prognosis in patients.We performed large cohort study 1069 patients. The Kaplan-Meier method was used calculate cumulative survival rate. Cox proportional hazard regression models were analyze associated with adjusting for clinicopathologic variables.MetS identified...
Sentinel lymph node (SLN) biopsy has been used to assess patients with papillary thyroid carcinoma (PTC). To achieve its full potential the rate of SLN identification must be as close 100 percent possible. In present study we compared combination preoperative lymphoscintigraphy scanning by sulfur colloid labeled 99 m Technetium, gamma-probe guided surgery, and methylene blue blue, alone, for sentinel in younger women unilateral low-risk PTC.From January 2004 2007, 90 female patients, ages 23...
Nonalcoholic fatty liver disease (NAFLD) is known to be associated with an increased risk of colorectal cancer (CRC). However, the relationship between NAFLD and prognosis CRC remains unclear. The primary objective this study was evaluate overall survival (OS) disease-free (DFS) rates in patients secondary compare clinicopathologic variables which were stratified by NAFLD. We performed a large cohort 1314 who first diagnosed January 2006 April 2011. Postoperative follow-up data collected...
Background and Aims There is no prognostic model that reliable practical for patients who have received curative liver resection (CLR) hepatocellular carcinoma (HCC). This study aimed to establish validate a Surgery-Specific Cancer of the Liver Italian Program (SSCLIP) scoring system those patients. Methods 668 eligible underwent CLR HCC from five separate tertiary hospitals were selected. The SSCLIP was constructed training cohort by adding independent predictors identified Cox proportional...
This study aims to investigate the impact of psammoma body (PB) on papillary thyroid carcinoma (PTC), and evaluate association among PB, Hashimoto thyroiditis (HT), other clinicopathologic characteristics in PTC patients. We conducted a retrospective case-control involving 1052 patients who underwent total thyroidectomy or lobectomy with lymph node dissection. Psammoma was observed 324 out (30.8%) Ultrasonographic (US) calcification (P < 0.001), multifocality tumor = 0.047), metastasis (LNM)...
The aim of this study was to evaluate the prognostic value both platelet lymphocyte ratio (PLR) and metabolic syndrome (MetS) in colorectal cancer (CRC) patients.We retrospectively enrolled 1,163 CRC patients. Preoperative values PLR were stratified into three groups according cut-off 120 220. Kaplan-Meier analysis used calculate cumulative survival rate related MetS. Cox proportional hazard regression models analyze potential risk factors prognosis associated with MetS patients.PLR...