A5100672254- Traditional Chinese Medicine Analysis
- Neuroinflammation and Neurodegeneration Mechanisms
- Diabetic Foot Ulcer Assessment and Management
- Liver Disease Diagnosis and Treatment
- Wound Healing and Treatments
- Mesenchymal stem cell research
- Cancer, Lipids, and Metabolism
- Immune Response and Inflammation
- Hepatocellular Carcinoma Treatment and Prognosis
- Prenatal Substance Exposure Effects
- Machine Learning in Bioinformatics
- Myasthenia Gravis and Thymoma
- Bacterial Identification and Susceptibility Testing
- Fatty Acid Research and Health
- Cannabis and Cannabinoid Research
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Second Language Acquisition and Learning
- Helicobacter pylori-related gastroenterology studies
- Chronic Kidney Disease and Diabetes
- Alkaloids: synthesis and pharmacology
- Healthcare professionals’ stress and burnout
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Heme Oxygenase-1 and Carbon Monoxide
- Flavonoids in Medical Research
- Nanoplatforms for cancer theranostics
Jianghan University
2021-2025
University of York
2024
East China University of Political Science and Law
2024
Lanzhou University
2020-2024
Indiana University Bloomington
2020-2024
Jiangxi University of Science and Technology
2024
First Hospital of Lanzhou University
2023-2024
Nanjing Medical University
2024
Xuzhou Medical College
2024
Second People’s Hospital of Huai’an
2024
Diabetic skin ulcer is one of the severe complications diabetes mellitus, which has a high incidence and may cause death or disability. Platelet-rich plasma (PRP) widely used in treatment diabetic wounds due to effect growth factors (GFs) derived from it. However, relatively short half-life GFs limits their applications clinics. In addition, presence large amount proteases wound microenvironment results degradation GFs, further impedes angiogenesis healing. our study, we fabricated...
Abstract The high morbidity and mortality of colorectal cancer (CRC) is a major challenge in clinical practice. Although series alternative research models CRC have been developed, appropriate orthotopic animal that reproduce the specific response as well pathophysiological immune features are still lacking. In current study, we constructed xenograft model by implanting tumor tubes at colorectum mice monitored development using bioluminescence imaging. This successfully recapitulates...
Neuroinflammation and microglial activation have been implicated in both alcohol use disorders (AUD) fetal spectrum (FASD). Chemokine monocyte chemoattractant protein 1 (MCP-1) its receptor C-C chemokine type 2 (CCR2) are critical mediators of neuroinflammation activation. FASD is the leading cause mental retardation, one most devastating outcomes loss neurons central nervous system (CNS). The underlying molecular mechanisms, however, remain unclear. We hypothesize that MCP-1/CCR2 signaling...
Background and study aims Preoperative biliary drainage of hilar cholangiocarcinoma (HC) is controversial. The goal this was to compare the clinical outcome associated complications for types II, III, IV HC managed by percutaneous transhepatic (PTBD) endoscopic retrograde cholangiopancreatography (ERCP). Patients methods Between January 2011 June 2017, a total 180 patients with were enrolled in retrospective cohort study. According method, divided into two groups: PTBD (n = 81) ERCP 99)....
In Chinese herbal medicine, Tanshinone IIA (Tan-IIA) is one of the main compounds extracted from Salvia miltiorrhiza Bunge. Tan-IIA has been demonstrated to inhibit growth various tumors. However, detailed molecular and cellular mechanisms antitumor effect have yet be fully illuminated.A2780 ID-8 were treated with 0, 1.2, 2.4, 4.8, or 9.6 µg/mL for 24 hours. Cell counting Kit-8 assay EdU staining used evaluate cell proliferation. Terminal deoxynucleotidyl transferase dUTP nick end labeling...
Abstract Interspecies cloning might be used as an effective method to conserve endangered species and support the study of nuclear–cytoplasm interaction. In this study, we describe development takin–bovine embryos in vitro produced by fusing takin ear fibroblasts with enucleated bovine oocytes examine fate mitochondrial DNA these embryos. We also compare blastocyst yak–bovine bovine–bovine cell numbers blastocyst. Our results indicate that: (1) cloned can develop stage (5%), (2) mitochondria...
Diabetic foot ulcer (DFU) is biggest life threats globally and increases their severity health complications for of patients. The present study was investigated to recover the wound healing activity baicalin in STZ-induced DFU rats by evaluating biochemical molecular markers. experimental animals induced with diabetes excision wounds were treated different doses (25, 50, 100 mg/kg). serum glucose level, body weight food intake measured. In addition, rat groups showed decreased increased...
Paclitaxel is a widely used clinical first line chemotherapy drug for ovarian carcinoma. Tanshinone I (Tan-I) one of the vital fat-soluble components, which derived from Chinese herbal medicine, Salvia miltiorrhiza Bunge. Herein, we evaluated whether Tan-I could enhance efficacy cancer to Paclitaxel.Ovarian cells A2780 and ID-8 were exposed with (4.8 µg/mL), (0.1 or combination 24 hours. The cell proliferation was analyzed by CCK8 EdU staining. Cell apoptosis TUNEL assay flow cytometry....
The present study aimed to investigate the effect and underlying mechanisms of Ruyi Zhenbao pill on neurological function following cerebral ischemia/reperfusion in rats. Male Sprague‑Dawley rats underwent middle artery occlusion reperfusion. received intragastrically either sodium carboxymethyl cellulose (control model groups) or at doses 0.2, 0.4 0.8 g/kg. Neurological was assessed by cylinder, adhesive beam‑walking tests after 14‑day treatment. Neurogenesis angiogenesis were detected...
The present study investigated the prevalence characteristics of oxacillin susceptible mecA-positive Staphylococcus aureus (OS-MRSA) in a children's hospital Kunming from January 2019 to December 2020.A total 499 S. strains were included and tested for susceptibility using VITEK 2 Compact automated antimicrobial test system. All oxacillin-susceptible detected mecA mecC by polymerase chain reaction (PCR). E-test was used compare minimum inhibitory concentration (MIC) values...
Purpose: To study the effect of Clematis chinensis extract (CCE) on diabetic nephropathy in rats.Methods: Eight-week old male Wistar rats were injected with streptozotocin to induce diabetes. The effects CCE(250 or 500 mg/kg) renal function index, fasting blood glucose (FBG), fat, oxidation and pathological kidney changes for 3 weeks compared those positive control drug, captopril.Results: At 12 weeks, CCE(500 treatment had significantly decreased serum urea nitrogen (BUN, 12.61 ± 1.42...
Background and objectivesThe most often encountered kind of liver cancer is hepatocellular carcinoma (HCC), in which distant metastases (DM) continue to result a worse prognosis. The present study aims determine the prognostic predictive factors DM patients with HCC, generate two nomograms assess occurrence probability prognosis HCC DM.
Abstract Background Patients with chronic diseases exhibit a heightened interest in seeking health information, and access to high-quality information can positively impact clinical outcomes. While previous research on static internet text/video has highlighted concerns about low-barrier creation leading low-quality content, it remains uncertain whether similar issues persist responses generated by Large Language Models (LLMs). Assessing the ability of LLMs responding medical queries...
JESLA is the Journal of European Second Language Association (EuroSLA). It publishes high-quality, peer-reviewed open-access articles in field second language research. Its aim to maintain a uniquely transdisciplinary approach promoting understanding learning and use, stimulating debate on bilingual multilingual individual society. one continuous issue per year, comprising best research from EuroSLA community.Each year submission awarded Best Article Prize, based peer review ratings its...
Background New Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations without a race adjustment were developed to estimate the glomerular filtration rate (eGFR). We aimed compare performance of five CKD-EPI eGFR equations, with or race, in predicting cardiovascular disease (CVD) events and all-cause mortality Black Americans from Jackson Heart Study. Methods JHS is an ongoing population-based prospective cohort study African Jackson, Mississippi, metropolitan area. Five used...
患者男,64岁.体检发现纵隔肿块1个月于2010年10月20日人院.患者偶有活动后胸闷、心慌、呼吸困难.胸部CT示前上纵隔类圆形软组织密度肿块,直径4 cm,内见片状低密度影,肿块境界清楚,周围见点状钙化灶.肺内未见占位性病变,肺门影不大,胸腔无积液(图1).全腹部B超及CT未见异常,胃肠内镜未见异常。