A5037738610- Dermatology and Skin Diseases
- Food Quality and Safety Studies
- Phytochemicals and Antioxidant Activities
- Allergic Rhinitis and Sensitization
- Advancements in Battery Materials
- Bone Metabolism and Diseases
- Animal Genetics and Reproduction
- Ginseng Biological Effects and Applications
- Endodontics and Root Canal Treatments
- Advanced Battery Materials and Technologies
- Biochemical effects in animals
- Advanced Battery Technologies Research
- Material Properties and Applications
- Seaweed-derived Bioactive Compounds
- Supercapacitor Materials and Fabrication
- Gut microbiota and health
- Bioactive Compounds and Antitumor Agents
- Organic Electronics and Photovoltaics
- Viral Infectious Diseases and Gene Expression in Insects
- Conducting polymers and applications
- Dental materials and restorations
- Spectroscopy and Chemometric Analyses
- Psoriasis: Treatment and Pathogenesis
- Agriculture, Soil, Plant Science
- Membrane-based Ion Separation Techniques
Korea Maritime and Ocean University
2013-2025
Jeju National University
2024
Yonsei University
2024
Sangji University
2021-2024
Kyung Hee University
2023-2024
Ansan University
2024
Korea University
2018-2024
Gyeongsang National University
2010-2024
Biosolution (South Korea)
2024
Shinshu University
2023
Mitochondrial NADP+-dependent isocitrate dehydrogenase 2 (IDH2) is a major NADPH-producing enzyme which essential for maintaining the mitochondrial redox balance in cells. We sought to determine whether IDH2 deficiency induces dysfunction and modulates auditory function, investigated protective potential of an antioxidant agent against reactive oxygen species (ROS)-induced cochlear damage Idh2 knockout (Idh2-/-) mice. leads damages hair cells spiral ganglion neurons (SGNs) cochlea ultimately...
This study aimed to demonstrate the anti-obesity effect of <italic>Plocamium telfairiae</italic> (PT), a red seaweed.
Among their several unique properties, the high electrical conductivity and mechanical strength of carbon nanofibers make them suitable for applications such as catalyst support fuel cells, flexible electrode materials secondary batteries, sensors. However, performance requires improvement practical applications. Several methods have been pursued to achieve this, growing nanotubes from nanofibers; however, transition metal used grow causes problems, including side reactions. This study...
We compared calcium silicate-based pulp capping materials to conventional hydroxide in terms of their biological properties and potential effects on odontogenic differentiation human dental stem cells (hDPSCs). cultured hDPSCs disks (7-mm diameter, 4-mm high) ProRoot MTA (Dentsply Tulsa Dental Specialties), Biodentine (Septodont), TheraCal LC (Bisco), or Dycal Specialties). Cell viability was assessed with cell counting (CCK) scanning electron microscopy (SEM). Odontogenic activity by...
Two new phenylspirodrimane derivatives, stachybotrysin (1) and stachybotrylactone B (2), were isolated from the cultures of marine-derived fungus Stachybotrys sp. KCB13F013. The structures determined by analyzing spectroscopic data (1D 2D NMR MS) chemical transformation, including modified Mosher's method single-crystal X-ray structure analysis. Compound 1 exhibited an inhibitory effect on osteoclast differentiation in bone marrow macrophage cells via suppressing RANKL-induced activation...
Bone homeostasis is tightly regulated to balance bone formation and resorption. Many anabolic drugs are used as bone-targeted therapeutic agents for the promotion of osteoblast-mediated or inhibition osteoclast-mediated Previous studies showed that ginsenoside Re has effect suppression osteoclast differentiation in mouse bone-marrow derived macrophages zebrafish. Herein, we investigated whether affects osteoblast mineralization vitro vivo models. Mouse precursor MC3T3-E1 cells were...
C-encapsulated highly pure Ni, Co, and Fe magnetic nanoparticles (MNPs/C) were synthesized by an innovative one-step in-situ plasma in liquid method (solution processing, SPP) without any additional reductants, agents, or treatment. Successful encapsulation of MNPs was demonstrated using inductively coupled plasma-atomic emission spectrometry cyclic voltammetry techniques. The obtained X-ray diffraction patterns transmission electron microscopy images corresponded to with average diameters 5...
Oleanolic acid (OA) is a pentacyclic triterpenoid, abundantly found in plants of the Oleaceae family, and well known for its beneficial pharmacological activities. Previously, we reported inhibitory effect OA on mast cell-mediated allergic inflammation. In this study, investigated effects atopic dermatitis (AD)-like skin lesions underlying mechanism action. We evaluated AD-like responses possible mechanisms using 1-chloro-2,4-dinitrochlorobenzene (DNCB)-induced AD animal model tumor necrosis...
In this study, we examined whether Hanganutziu-Deicher (H-D) antigens are important as an immunogenic non-α1,3-galactose (Gal) epitope in pigs with a disrupted α1,3-galactosyltransferase gene. The targeting efficiency of the AO blood genotype was achieved (2.2%) pig fibroblast cells. A total 1800 somatic cell nuclear transfer (SCNT) embryos were transferred to 10 recipients. One recipient developed term and naturally delivered two piglets. activity lung, liver, spleen, testis heterozygote...
Targeting specific cell types in the mammalian inner ear is important for treating genetic hearing loss due to different type-specific functions. Adeno-associated virus (AAV) an efficient vivo gene transfer vector, and it has demonstrated promise loss. Although more than 100 AAV serotypes have been identified, few studies investigated whether can be distributed types. Here we screened three EGFP-AAV reporter constructs (serotypes DJ, DJ8, PHP.B) neonatal by injection via round window...
Atopic dermatitis (AD) is a kind of inflammation on the skin following with swollen, itchy, dryness and cracked skin. Though exact cause AD unknown, there are evidence that people have compromised barrier along inflammation. Eclipta prostrata Linné traditional herbal medicinal plant, has been used for diabetes, obesity, jaundice, We supposed E. L. an anti-inflammatory effect skin.We aimed to assess EtOH extract (EP) elucidate associated molecular mechanisms.The EP mechanisms were eluciated...
Although hepatocyte-like cells derived from human pluripotent stem (hPSC-HLCs) are considered a promising model for predicting hepatotoxicity, their application has been restricted because of the low activity drug metabolizing enzymes (DMEs). Here we found that expression xenobiotic receptors (constitutive androstane receptor, CAR; and pregnane X PXR) contributes to DMEs in hPSC-HLCs. Most CAR- PXR-regulated transporters were transcriptionally down-regulated hPSC-HLC. Transcriptional CAR PXR...
The developing brain of a neonate is particularly susceptible to damage by vitamin C deficiency because its rapid growth and immature antioxidant system. Cognitive impairment sensory motor deficits are found in the adult upon deficiency. Therefore, aim this study was clarify role own right related mechanisms Gulo(-/-) mice incapable synthesizing C.When supplementation ceased for 2 weeks until delivery, stillbirths significant reduction neonatal were observed neonates remarkably decreased. In...
Luteolin was gamma irradiated at doses of 0, 15, 30, 50, 70, and 100 kGy. We observed that the luteolin peak decreased simultaneously with appearance new radiolytic peaks, using high-performance liquid chromatography (HPLC). The highest (GLM) product in gamma-irradiated a dose 70 kGy, GLM identified by nuclear magnetic resonance high-performance-liquid-chromatography-quadrupole-time-of-flight (HPLC-Q-TOF) mass spectrometry. examined whether kGy has more effective anti-melanogenic effects...
Chan-Mi Park, Hye-Min Kim, Dong Hyun Ho-Jin Han, Haneul Noh, Jae-Hyuk Jang, Soo-Hyun Han-Jung Chae, Soo-Wan Eun Kyoung Ryu, Sangku Lee, Kangdong Liu, Haidan Jong-Seog Ahn, Young Ock Bo-Yeon and Nak-Kyun Soung. Mol. Cells 2016;39:855-61. https://doi.org/10.14348/molcells.2016.0111
Purpose: The changes in molecular structure and the physiological properties of a gamma-irradiated aloe-emodin were examined.Materials methods: Aloe-emodin was at doses ranging from 0 to 150 kGy, then analyzed using high-performance liquid chromatography (HPLC). AGS cells cultured RPMI medium treated gamma irradiated aloe-emodin. Cell viability measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. Apoptosis efficiency investigated cell cycle arrest,...