A5019238109- Inflammatory Bowel Disease
- Microscopic Colitis
- Eosinophilic Esophagitis
- Abdominal Surgery and Complications
- Intestinal and Peritoneal Adhesions
- Breastfeeding Practices and Influences
- Protein Kinase Regulation and GTPase Signaling
- Cardiac pacing and defibrillation studies
- TGF-β signaling in diseases
- Gastroesophageal reflux and treatments
- Child and Adolescent Health
- Pharmaceutical industry and healthcare
- Diverticular Disease and Complications
- Innovations in Medical Education
- Prion Diseases and Protein Misfolding
- COVID-19 and healthcare impacts
- Esophageal and GI Pathology
- Emergency and Acute Care Studies
- Rheumatoid Arthritis Research and Therapies
- Dysphagia Assessment and Management
- Appendicitis Diagnosis and Management
- Liver physiology and pathology
- Spondyloarthritis Studies and Treatments
- Cardiac Arrhythmias and Treatments
- Simulation-Based Education in Healthcare
Peterborough City Hospital
2024
New York University
2024
Modern University for Information and Technology
2023
Médecins Sans Frontières
2023
King's College London
2005-2021
Southwestern Medical Center
2017-2020
The University of Texas Southwestern Medical Center
2014-2020
Advocate Children's Hospital
2020
Salford Royal Hospital
2019
Crescent University
2019
OBJECTIVES Ear, nose, and throat (ENT) physicians often diagnose gastroesophageal reflux disease (GERD)-related laryngitis on the basis of symptoms laryngeal signs; may refer patients to gastroenterologists who contend that many such do not have reflux. Because this dichotomy we designed study assess practice pattern differences among ENT in relation diagnosis treatment with GERD-related laryngitis. METHODS Separate surveys were specifically for following: percentage diagnosed laryngitis,...
Small bowel obstruction is a common surgical emergency, and associated with high levels of morbidity mortality across the world. The literature provides little information on conservatively managed group. aim this study was to describe burden small in UK. This prospective cohort conducted 131 acute hospitals UK between January April 2017, delivered by trainee research collaboratives. Adult patients diagnosis mechanical were included. primary outcome in-hospital mortality. Secondary outcomes...
The Impella LP 2.5 (Abiomed, Danvers, MA) has been a tool of use for high risk coronary procedures and cardiogenic shock. As with any invasive or intracardiac device, improper placement can result in disastrous complications. Hemolytic anemia secondary to implantation is one the documented However, cases severe hemolytic are rare literature. Proven imaging modalities like ultrasound need be used guide proper placement. We present case device induced hemolysis due insertion guidance avoid...
Summary Background Hyperbaric oxygen has been reported to improve disease activity in hospitalised ulcerative colitis (UC) patients. Aim To evaluate dosing strategies with hyperbaric for UC Methods We enrolled patients acute flares (Mayo score 6‐12). Initially, all received 3 days of at 2.4 atmospheres (90 minutes two air breaks) addition intravenous steroids. Day responders (reduction partial Mayo ≥ 2 points and rectal bleeding 1 point) were randomised receive a total 5 vs oxygen. Results...
An important process in embryogenesis and cancer-cell metastasis is the conversion of epithelial cells to a migratory phenotype, phenomenon known as epithelial-mesenchymal transition (E-MT). To achieve E-MT, dissociate from neighbouring adopt morphology. This requires remodelling their cell shape substratum adhesions; activities that require extensive reorganisation actin cytoskeleton. Hepatocyte growth factor (HGF)-induced scattering Madin Darby canine kidney (MDCK) routinely used model...
Breastfeeding (BF) should be protected, promoted, and supported for all infants in humanitarian settings. The re-establishment of exclusive BF is also a central part the management acutely malnourished under 6 months (<6 m). Médecins Sans Frontières (MSF) runs nutrition project Maiduguri, protracted emergency setting North-East Nigeria. This study aimed to explore caregivers' (CGs) health workers' (HWs) perceptions practice, promotion, support among CGs with <6 m this setting.We conducted...
Abstract Background Abdominal wall hernia is a common surgical condition. Patients may present in an emergency with bowel obstruction, incarceration or strangulation. Small obstruction (SBO) serious condition associated significant morbidity. The aim of this study was to describe current management and outcomes patients obstructed the UK as identified National Audit Bowel Obstruction (NASBO). Methods NASBO collated data on adults treated for SBO at 131 hospitals between January March 2017....
Abstract Objective Individuals of racially and ethnically diverse backgrounds are underrepresented in PsA research/clinical trials, despite evidence that their disease presentation, severity course may be distinct. Here we aim to describe how race, ethnicity other socioeconomic factors inform characteristics PsA. Methods A total 817 consecutive patients with from a large, metropolitan area were enrolled an observational, longitudinal registry. Demographics, medical history, medication use...
Context.— Conflicting data about the clinical significance of microscopic Crohn disease (CD) activity at resection margins have led to varying practice patterns for routine reporting by pathologists. Objective.— To characterize association between active with postoperative CD recurrence and time-to-recurrence in era anti–tumor necrosis factor therapy. Design.— We performed a multicenter retrospective cohort study 101 consecutive bowel resections during 10 years. Margin slides were reviewed,...
Creutzfeldt-Jakob disease (CJD) is a fatal neurodegenerative disorder that leads to rapid cognitive decline, dementia, and neurological deterioration. CJD has several forms, including sporadic (sCJD), which accounts for most cases, variant (vCJD), linked exposure bovine spongiform encephalopathy (BSE or mad cow disease). The caused by abnormal prion proteins, damage the brain lead death. universally fatal, with no cure, cases are within few months year after diagnosis. We present 64-year-old...
Introduction: Supraventricular tachycardia (SVT) is a condition requiring emergency care in neonates. Case Report: We describe successfully treated case of neonatal SVT four-week-old neonate using the novel adenosine administration method. This technique potentially easier to facilitate and does not require equipment such as stopcock. Adenosine 0.2 milligrams per kilogram was drawn up into syringe containing 0.9% sodium chloride total volume 3 milliliters. Once administered, patient had...
Introduction: Inflammatory bowel disease (IBD) is increasing among Hispanic patients; however few studies have examined differences in epidemiology, severity, and treatment course between non-Hispanic patients. Our aim was to evaluate ethnicity as a clinically significant variable influencing need for anti-TNF ±immunomodulator therapy, rates of surgery, hospitalizations. Methods: A cohort adult IBD patients followed large urban safety-net hospital January 2007 December 2012 identified. The...
Introduction: The rate of hospitalization and/or surgery in inflammatory bowel disease (IBD) varies widely between patients and centers. aim our study was to identify factors affecting these outcomes 2 different patient care settings. Methods: We conducted a multi-center retrospective cohort among IBD followed at one large urban hospital systems- university-based practice safety-net hospital. Two authors extracted demographics, clinical characteristics, endoscopic data, clinic utilization,...
Purpose: The majority of patients with Crohn's disease (CD) require intestinal resection during their course. However, recurrence rates are high, and other than smoking the creation an anastomosis, no well replicated risk factors have been identified. In this study, we sought to determine whether CD-associated genetic variants predict surgical CD. Methods: 94 CD who had undergone ileocolic resections anastomosis were included. Post-operative was defined as a second diseased bowel in order...