A5101853590- Zeolite Catalysis and Synthesis
- Circadian rhythm and melatonin
- Mesoporous Materials and Catalysis
- interferon and immune responses
- Catalytic Processes in Materials Science
- Behavioral Health and Interventions
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Metal-Organic Frameworks: Synthesis and Applications
- Heart Rate Variability and Autonomic Control
- Sleep and related disorders
- Cervical Cancer and HPV Research
- scientometrics and bibliometrics research
- Online Learning and Analytics
- RNA Interference and Gene Delivery
- RNA modifications and cancer
- Catalysis for Biomass Conversion
- Non-Invasive Vital Sign Monitoring
- Sleep and Work-Related Fatigue
- Cancer-related molecular mechanisms research
- Reproductive tract infections research
- Genital Health and Disease
- Machine Learning in Healthcare
- Security and Verification in Computing
- Gene Regulatory Network Analysis
The University of Melbourne
2025
Southern University of Science and Technology
2025
Shaoxing City Women and Children Hospital
2025
Tianjin University
2020-2024
Wenzhou Central Hospital
2017-2024
Unité Matériaux et Transformations
2023-2024
Zhejiang University
2024
Northwestern University
2022-2024
Wenzhou Medical University
2024
Quantitative BioSciences
2022-2023
The virus SARS-CoV2, which causes coronavirus disease (COVID-19) has become a pandemic and spread to every inhabited continent. Given the increasing caseload, there is an urgent need augment clinical skills in order identify from among many mild cases few that will progress critical illness. We present first step towards building artificial intelligence (AI) framework, with predictive analytics (PA) capabilities applied real patient data, provide rapid decision-making support. COVID-19...
Abstract Wearable, multisensor, consumer devices that estimate sleep are now commonplace, but the algorithms used by these to score not open source, and raw sensor data is rarely accessible for external use. As a result, limited in their usefulness clinical research applications, despite holding much promise. We mobile application of our own creation collect acceleration heart rate from Apple Watch worn participants undergoing polysomnography, as well during ambulatory period preceding lab...
Abstract Colloidal quantum dots (CQDs) are attractive gain media due to their wavelength-tunability and low optical threshold. Consequently, CQD lasers, especially the surface-emitting ones, promising candidates for display, sensing communication. However, it remains challenging achieve a low-threshold laser array with high stability integration density. For this purpose, is necessary combine improvement of material cavity. Here, we have developed high-quality core/interlayer/graded shell...
A critical barrier to successful treatment of circadian misalignment in shift workers is determining phase a clinical or field setting. Light and movement data collected passively from wrist actigraphy can generate predictions via mathematical models; however, these models have largely been tested non-shift working adults. This study the feasibility accuracy predicting dim light melatonin onset (DLMO) fixed night workers.
From smart work scheduling to optimal drug timing, there is enormous potential in translating circadian rhythms research results for precision medicine the real world. However, pursuit of such effort requires ability accurately estimate phase outside laboratory. One approach predict noninvasively using light and activity measurements mathematical models human clock. Most take as an input effect on system. consumer-grade wearables that are already owned by millions individuals record instead...
Millions of wearable-device users record their heart rate (HR) and activity. We introduce a statistical method to extract track six key physiological parameters from these data, including an underlying circadian rhythm in HR (CRHR), the direct effects activity, meals, posture, stress through hormones like cortisol. test our on over 130,000 days real-world data medical interns rotating shifts, showing that CRHR dynamics are distinct those sleep-wake or physical activity patterns vary greatly...
Histone deacetylase 10 (HDAC10) is a member of the class II HDACs, and its role in cancer emerging. In this study, we found that HDAC10 highly expressed lung tissues. It resides mainly cytoplasm cells but nucleus adjacent normal cells. Further examinations revealed multiple cell lines, including A549, H358 H460 epithelial 16HBE A leucine-rich motif, R505L506L507C508V509A510L511, was identified as nuclear localization signal (NLS), mutant (Mut-505-511) featuring mutations to at each original...
Abundant epidemiological evidence links circadian rhythms to human health, from heart disease neurodegeneration. Accurate determination of an individual's phase is critical for precision diagnostics and personalized timing therapeutic interventions. To date, however, we still lack assay physiological time that accurate, minimally burdensome the patient, readily generalizable new data. Here, present TimeMachine, algorithm predict using gene expression in peripheral blood mononuclear cells a...
Environmental, Social and Governance (ESG) factors have gained significance in investment strategies within modern finance. As a result, integrating ESG compliant portfolio optimization has been increasingly adopted among investors when combining with conventional financial indicators. This research is step toward meeting this crucial need for respect to the conformance of rating, advancing fairer more responsible global economy. study also focuses on developing Model composite score. By...
Primary liver cancer is associated with high morbidity and mortality rate. In about 50% of cases, primary related to the phosphoinositide-3-kinase (PI3K)/Akt signaling pathway. Wogonoside an active component extracted from Scutellaria baicalensis. Its antitumor effects in are scarcely known. This study explores correlation between wogonoside PI3K/Akt pathway vitro. THLE-2 cells HepG2 were treated different concentrations establish low-, medium- high- dose groups, concentration each group was...
This report presents Wan, a comprehensive and open suite of video foundation models designed to push the boundaries generation. Built upon mainstream diffusion transformer paradigm, Wan achieves significant advancements in generative capabilities through series innovations, including our novel VAE, scalable pre-training strategies, large-scale data curation, automated evaluation metrics. These contributions collectively enhance model's performance versatility. Specifically, is characterized...
Angiogenesis and inflammation are regarded as important factors in the pathogenesis of chronic inflammation, cancer, wound healing. Recent studies have supported prior evidence that common signaling pathways involved angiogenesis inflammatory responses; however, key controlling both processes remain unclear. Although tripartite motif-containing (TRIM)-28 is known to an immunosuppressive role immune cells, its expression level endothelial cells (ECs) still In this study, we investigated...
The market value of real estate is difficult to predict with simple regression model due the diversity and complexity data. In this paper, latest data three counties in Los Angeles, California, United States, both linear non-linear machine learning methods are employed log error home value. motivation improve accuracy prediction advanced methods. main contribution that it finds traditional models not predictive for complex sets, while tree based most accurate lowest mean square errors.
Lipogenesis is required for the optimal growth of many types cancer cells, it shown to control biosynthesis lipid bilayer membrane during rapid proliferation and metastasis, provides cells with signaling molecules support development make more resistant oxidative stress-induced cell death. Though multiple lipogenic enzymes have been identified mediate this metabolic change, how expression these are transcriptionally regulated remains unclear. Gain- loss-of-function experiments were conducted...
To achieve a better catalytic performance, it is of great interest to synthesize nanosized zeolites with reduced internal diffusion limitations. Herein, c-axis shortened wheel-like mordenite nanoassemblies were synthesized. The crystal growth along the [001] direction was successfully inhibited K+ cations as structure breaking agents. 1.5–2 μm in diameter and 200–300 nm thickness. such unique underwent nonclassical crystallization process including generation amorphous worm-like particles...
Abstract Background Cuproptosis induces proteotoxic stress and eventually leads to cell death. However, the relationship between cuproptosis lncRNAs in cervical cancer has not been fully elucidated. Therefore, we aim explore association among lncRNAs, clinical features cancer. Methods RNA sequencing, genetic mutations, data of CESC patients were obtained from TCGA. Cuproptosis-associated genes gathered. WGCNA was used cluster important modules, KEGG, GO, GSEA GSVA functional pathway...
Sprouting angiogenesis is a highly coordinately process controlled by vascular endothelial growth factor receptor (VEGFR)-Notch signaling. Here we investigated whether Tripartite motif-containing 28 (TRIM28), which an epigenetic modifier implicated in gene transcription and cell differentiation, essential to mediate sprouting angiogenesis. We observed that knockdown of TRIM28 ortholog zebrafish resulted developmental defect with disorganized reduced vasculatures. Consistently, inhibited...