A5017542110- Immunotherapy and Immune Responses
- Advanced Computing and Algorithms
- E-commerce and Technology Innovations
- Advanced Control Systems Design
- Occupational Health and Safety Research
- Cancer Immunotherapy and Biomarkers
- Multicomponent Synthesis of Heterocycles
- Healthcare professionals’ stress and burnout
- Cancer, Stress, Anesthesia, and Immune Response
- Synthesis of heterocyclic compounds
- CAR-T cell therapy research
- Maternal Mental Health During Pregnancy and Postpartum
- RNA Interference and Gene Delivery
- Liver physiology and pathology
- Pelvic floor disorders treatments
- Reproductive Health and Contraception
- Renin-Angiotensin System Studies
- Protease and Inhibitor Mechanisms
- Advanced Adaptive Filtering Techniques
- Sleep and Work-Related Fatigue
- Cancer Cells and Metastasis
- Workplace Health and Well-being
- Synthesis and biological activity
- Peptidase Inhibition and Analysis
- Power System Optimization and Stability
Capital Medical University
2017-2024
Shanghai East Hospital
2023-2024
Jinzhou Medical University
2023
State Grid Corporation of China (China)
2017
Jilin Electric Power Research Institute (China)
2017
Dali University
2016
Tianjin Central Hospital of Gynecology Obstetrics
2012
Beijing Geriatric Hospital
2009
Legumain is a member of the asparaginyl endopeptidase family that over-expressed in response to hypoxic stress on mammary adenocarcinoma, colorectal cancer, proliferating endothelial cells, and tumor-associated macrophages (TAMs). Here, we demonstrate elevated expression legumain ovarian cancer by proteomic approach using isobaric tags for relative absolute quantification (iTRAQ) followed liquid chromatography-mass spectrometry (LC-MS/MS). To investigate relationship between development,...
mRNA neoantigen cancer vaccine inducing neoantigen-specific T cell responses holds great promise for immunotherapy; however, its clinical translation remains challenging because of suboptimal prediction accuracy and low delivery efficiency, which compromise the in vivo therapeutic efficacy. We present a lipopolyplex (LPP)–formulated encoding tandem neoantigens as regimen. The LPP-formulated vaccines elicited robust CD8 + three syngeneic murine tumor models (CT26, MC38, B16F10) to suppress...
A high tendency of intention to leave has been noted for nurses in China. The nursing profession is currently unstable.A sample 51406 from 311 hospitals China who completed the self-administered questionnaire online was recruited via Nursing Association by email and phone using a simple random sampling method. recruitment occurred between July 2016 2017.The majority had working experience ≤20 years work on night shifts. percentage (71.8%) insomnia, followed 37.0% developed varicose veins...
In liver cancer, leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) compartment represents an important tumor-initiating cell (TIC) population and served as a potential therapeutic target. Cancer-associated fibroblasts (CAFs) is critical part of the tumor microenvironment, heavily influenced TIC function fate. However, deeply investigations have been hindered by lack accurate preclinical models to investigate interaction between CAFs TIC. Organoids model achieved major...
Accessing good quality abortion care is a fundamental human right and contributes to achieving Sustainable Development Goals. However, well-designed that meets women’s needs limited. This study aims systematically develop an intervention promote the psychological well-being of Chinese women undergoing abortion. A five-step iterative approach informed by mapping was undertaken determine design. Step 1 used in-depth interviews with 14 assess real-life stressors support needs. We identified...
The online identification of power system dominated inter-area oscillations interface based on the incremental energy function method is proposed in this paper. dominant can be obtained by calculating branch oscillation potential energy, which tie-line concentrated energy. To get caused different mechanism (free and forced oscillation), fault position, source. Power effectively method, at same time, clusters also obtained. Finally, damping property improved configurating series controller...
Abstract C 18 H N 2 O 5 , monoclinic, P 1 / n a = 8.605(5) Å, b 8.496(4) c 23.771(5) β 95.853(19)°, V 1728.7(12) Å 3 Z 4, R gt ( F ) 0.0461, wR ref 0.1309, T 296 K.
At present, the double-fed induction generator (DFIG) has been used in power system widely.Containing characteristics of strong nonlinearity and model uncertainty interconnected grid with doubly-fed wind generation system.In this paper, a simple fractional order PID wide-area damping controller is designed, to enhance control containing turbine, restrain oscillation.The additional can be add into DFIG damp oscillation it doesn't equipment.The remote-signal introduced wide area (WADC) DFIG,...
Objective To explore knowledge-attitude-practice of the pelvic floor muscle function training in puerperium women and current situation its needs, providing reference for carrying on clinical propaganda education puerperal rehabilitation therapies. Methods The self-designed Pelvic Floor Muscle Function Training Knowledge-Attitude-Practice Its Needs Puerperium Women Questionnairewas applied. One hundred fifty lying-in who were enrolled reexamination at 42 days after delivery...