A5100731373- Marine Biology and Ecology Research
- Microbial Community Ecology and Physiology
- Microplastics and Plastic Pollution
- Plant tissue culture and regeneration
- Environmental Quality and Pollution
- RNA Research and Splicing
- Molecular Biology Techniques and Applications
- Evaluation Methods in Various Fields
- Insect Resistance and Genetics
- Paleontology and Stratigraphy of Fossils
- Genomics and Chromatin Dynamics
- Environmental Changes in China
- Invertebrate Immune Response Mechanisms
- Transgenic Plants and Applications
- biodegradable polymer synthesis and properties
- RNA modifications and cancer
- Chromosomal and Genetic Variations
- Aquaculture disease management and microbiota
- Photosynthetic Processes and Mechanisms
- Environmental and Agricultural Sciences
- Graphene and Nanomaterials Applications
- Plant Molecular Biology Research
- Plant Pathogens and Fungal Diseases
- Lipid metabolism and biosynthesis
- Water Resources and Sustainability
Hainan Provincial Academy of Agricultural Sciences
2009-2025
Animal Science Research Institute
2025
Ocean University of China
2007-2024
Chinese Academy of Sciences
2014-2024
Second Hospital of Yichang
2024
Institute of Biophysics
2022-2024
Chinese PLA General Hospital
2024
Wuhan University
2023
Renmin Hospital of Wuhan University
2023
Hebei University of Chinese Medicine
2022
Bivalent genes are ready for activation upon the arrival of developmental cues. Here, we report that BEND3 is a CpG island (CGI)-binding protein enriched at regulatory elements. The cocrystal structure in complex with its target DNA reveals structural basis methylation-sensitive binding property. Mouse embryos ablated Bend3 died pregastrulation stage. null embryonic stem cells (ESCs) exhibited severe defects differentiation, during which hundreds CGI-containing bivalent were prematurely...
Abstract Microfilament and Ca2+ dynamics play important roles in stress signaling plants. Through genetic screening of Arabidopsis thaliana mutants that are defective stress-induced increases cytosolic ([Ca2+]cyt), we identified Actin-Related Protein2 (Arp2) as a regulator [Ca2+]cyt response to salt stress. Plants lacking Arp2 or other proteins the Arp2/3 complex exhibited enhanced salt-induced [Ca2+]cyt, decreased mitochondria movement, hypersensitivity salt. In addition, aggregated,...
Schematic illustration of the structure and drug release process a responsive cascade delivery scaffold (RCDDS) for peripheral nerve injury repair.
Abstract Motivation: Alzheimer’s disease (AD) is a severe neurodegenerative of the central nervous system that may be caused by perturbation regulatory pathways rather than dysfunction single gene. However, pathology AD has yet to fully elucidated. Results: In this study, we systematically analyzed AD-related mRNA and miRNA expression profiles as well curated transcription factor (TF) regulation identify active TF in AD. By mapping differentially expressed genes miRNAs network seed nodes,...
N6-methyladenosine (m6A) is the most prevalent internal modification present in mRNAs of all higher eukaryotes, where it within both coding and noncoding regions. In mammals, methylation requires catalysis a multicomponent m6A methyltransferase complex. Proposed biological functions for include pre-mRNA splicing, RNA stability, cell fate regulation, embryonic development. However, few studies have been conducted on trees. particular, regulation mechanism Populus development remains to be...
Non-motorised travel and public transportation are recognised as low-carbon modes, in contrast to car travel, which is considered a non-low-carbon option. Based on this, the paper proposes stratified assessment method for urban potential. The proportion of motorised population that could potentially shift non-motorised within entire defined Tier 1 Meanwhile, 2 This holistically presents potential improvement traffic carbon emission control. considers distance primary negative factor...
The genus Mallotus oblongifolius (MO), a member of the Euphorbia family, exhibits predominant distribution in Hainan Island and has been proven to possess diverse medicinal attributes. Research indicates that ultramicro-grinding fully exposes active ingredients oblongifolius, enhancing bioavailability efficacy, compared before. Our study investigates effects ultrafine powder (MOUP) on pigs. A total sixty-four healthy castrated pigs (ternary hybrid pigs, Duroc × Tunchang) with comparable...
Seed oil accumulates primarily as triacylglycerol (TAG). While the biochemical pathway for TAG biosynthesis is known, its regulation remains unclear. Previous research identified microsomal diacylglycerol acyltransferase 1 (DGAT1, EC 2.3.1.20) controlling a rate-limiting step in pathway. Of note, overexpression of DGAT1 results substantial increases content and seed size. To further analyze global consequences manipulating levels during development, concerted transcriptome metabolome...
When using the water‐based extraction processes (WBEPs) to recover bitumen from weathered oil sands, very low recovery arisen poor liberation of sand grains is always obtained. Application microbial enhanced (MEOR) technology in WBEPs solve processability ore was proposed. It found that microbial‐treated greatly improved. The improved attributed biosurfactants production culture solution, alteration solids wettability, degradation asphaltene component, and decrease viscosity, which...
Abstract BACKGROUND The two‐spotted spider mite Tetranychus urticae is a polyphagous and cosmopolitan pest that has developed high resistance to abamectin, making it difficult control. Although ‘target resistance’ related glutamate‐gated chloride channel mutations was found in T. field populations China, other mechanisms appear be involved. Here, we conducted genome‐wide transcriptome profiling using RNA‐sequencing of two abamectin‐resistant (NB‐ZJ SY‐BJ) one susceptible strain (Lab‐SS)...
Coastal estuaries and bays are exposed to both natural anthropogenic environmental changes, inflicting intensive stress on the microbial communities inhabiting these areas. However, it remains unclear how community diversity their eco-functions affected by disturbances rather than changes. Here, we explored sediment functional genes dynamics interaction networks in Hangzhou Bay (HZB), one of most severely polluted China's eastern coast. The results indicated key gene categories, including N,...
Epigenetic systems are well known for the roles they play in regulating differential expression of same genome different cell types. However, epigenetic can also directly impact genomic integrity by protecting genetic sequences. Using an experimental evolutionary approach, we studied rates mutation fission yeast Schizosaccharomyces pombe strains that lacked genes encoding several regulators or mismatch repair components. We report loss a functional pathway S. resulted preferential enrichment...
Reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR) is a technique widely used for the quantification of mRNA transcription, It well recognized that reference genes in RT‑qPCR require appropriate validation to ensure gene expression unaffected by experimental conditions. The differentiation bone mesenchymal stem cells (BMSCs) into neurons important treatment nerve injury. In analysis BMSCs neuronal by, commonly RNA are often selected without any preliminary evaluation...