- Advanced biosensing and bioanalysis techniques
- Electrochemical sensors and biosensors
- Advanced Nanomaterials in Catalysis
- 2D Materials and Applications
- Carbon and Quantum Dots Applications
- Nanocluster Synthesis and Applications
- Biosensors and Analytical Detection
- RNA Interference and Gene Delivery
- MicroRNA in disease regulation
- Lipid metabolism and biosynthesis
- Electrochemical Analysis and Applications
- Chalcogenide Semiconductor Thin Films
- Conducting polymers and applications
- Epigenetics and DNA Methylation
- Advanced ceramic materials synthesis
- Adipose Tissue and Metabolism
- Amino Acid Enzymes and Metabolism
- Molecular Sensors and Ion Detection
- Force Microscopy Techniques and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Molecular Junctions and Nanostructures
- Pesticide and Herbicide Environmental Studies
- Phytochemicals and Antioxidant Activities
- Microbial Metabolic Engineering and Bioproduction
- RNA and protein synthesis mechanisms
Hunan University of Technology
2019-2025
Shanghai Clinical Research Center
2021-2025
University of Chinese Academy of Sciences
2021-2025
Hunan University
2013-2024
Second Military Medical University
2023-2024
State Key Laboratory of Chemobiosensing and Chemometrics
2009-2024
South China University of Technology
2019-2024
South China Agricultural University
2024
Shandong Academy of Agricultural Machinery Sciences
2024
Sichuan University
2024
Chronic postsurgical pain (CPSP), an often unanticipated result of necessary and even life-saving procedures, develops in 5-10% patients one-year after major surgery. Substantial advances have been made identifying at elevated risk developing CPSP based on perioperative pain, opioid use, negative affect, including depression, anxiety, catastrophizing, posttraumatic stress disorder-like symptoms. The Transitional Pain Service (TPS) Toronto General Hospital (TGH) is the first to...
The excessive use of levofloxacin (LEV) can lead to significant environmental pollution, while also damaging human health. accurate detection its concentration is therefore essential protect both the environment and Herein, we report simple synthesis α-zirconium phosphate supported on nitrogen-doped graphene nanosheets (α-ZrP/NG) application in voltammetric determination trace LEV real samples. surface morphology, microstructure, electrochemical properties α-ZrP/NG were investigated by...
Detection of C-reactive protein using nanoparticle-enhanced surface plasmon resonance an aptamer-antibody sandwich assay.
A facile hydrothermal method is utilized to synthesize zinc oxide-reduced graphene oxide nanocomposites for an electrochemical hydrazine sensor.
The development of sensitive and stable electrochemical sensors toward dopamine is highly desirable. Herein, a novel voltammetric sensor was developed for the detection using shuttle-like α-Fe2O3 nanoparticles/electro-reduced graphene oxide nanocomposites (S-Fe2O3/ErGO). surface morphology, microstructure, chemical composition S-Fe2O3/ErGO were investigated by SEM, XRD Raman spectra, respectively. behavior Fe2O3/ErGO nanocomposite modified glass carbon electrode (S-Fe2O3/ErGO/GCE) studied...
Abstract A sensitive and specific electrochemical biosensor based on target‐induced aptamer displacement was developed for direct detection of Escherichia coli O111. The O111 immobilized a gold electrode by hybridization with the capture probe anchored surface through Au‐thiol binding. In presence O111, dissociated from probe‐aptamer duplex due to stronger interaction between consequent single‐strand could be hybridized biotinylated tagged streptavidin‐alkaline phosphatase, producing...
Multivalent protein–carbohydrate interactions initiate the first contacts between virus/bacteria and target cells, which ultimately lead to infection. Understanding structures binding modes involved is vital design of specific, potent multivalent inhibitors. However, lack structural information on such flexible, complex, multimeric cell surface membrane proteins has often hampered endeavors. Herein, we report that quantum dots (QDs) displayed with a dense array mono-/disaccharides are...
Abstract Uncooled broadband spectrum detection, spanning from visible to mid‐wave‐infrared regions, offers immense potential for applications in environmental monitoring, optical telecommunications, and radar systems. While leveraging proven technologies, conventional photodetectors are encumbered by high dark currents the necessity cryogenic cooling. Correspondingly, innovative low‐dimensional materials like black phosphorus manifest weak photoresponse instability. Here, tantalum nickel...
The aim of this study was to identify the mechanisms by which angiotensin II alters physiology pericyte‐containing microvasculature retina. Despite evidence that vasoactive signal regulates capillary perfusion inducing abluminal pericytes contract and thereby microvascular lumens constrict, little is known about events linking exposure with pericyte contraction. Here, using microvessels freshly isolated from adult rat retina, we monitored currents via perforated‐patch pipettes, measured...
A novel isothermal electrochemical biosensor was proposed for the sensitive detection of microRNA (miRNA) based on ingenious combination target-catalyzed hairpin assembly (CHA) and supersandwich amplification strategies. Since miRNA-221 has been reported to be overexpressed in cancers a potentially useful biomarker diagnosis related diseases, chosen as model target miRNA. The triggered toehold strand displacement two substrates, which led cyclicality miRNA CHA products. Subsequently,...