Beihua Bao

ORCID: 0000-0002-6067-3093
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About
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Research Areas
  • Traditional Chinese Medicine Analysis
  • Metabolomics and Mass Spectrometry Studies
  • Natural product bioactivities and synthesis
  • Bioactive Natural Diterpenoids Research
  • Phytochemistry and Biological Activities
  • Pharmacological Effects of Natural Compounds
  • Phytochemicals and Antioxidant Activities
  • Ginger and Zingiberaceae research
  • Bone Metabolism and Diseases
  • Food Quality and Safety Studies
  • Ginseng Biological Effects and Applications
  • Medicinal plant effects and applications
  • Essential Oils and Antimicrobial Activity
  • Plant-based Medicinal Research
  • Traditional Chinese Medicine Studies
  • Bee Products Chemical Analysis
  • Seaweed-derived Bioactive Compounds
  • Polysaccharides and Plant Cell Walls
  • Angiogenesis and VEGF in Cancer
  • Berberine and alkaloids research
  • Phytochemistry and Bioactive Compounds
  • Biosensors and Analytical Detection
  • Medicinal Plant Research
  • Drug Transport and Resistance Mechanisms
  • Advanced biosensing and bioanalysis techniques

Nanjing University of Chinese Medicine
2015-2024

DHC Software (China)
2024

Boston Children's Hospital
2024

Nanjing University
2014-2017

Wayne State University
1994

Soybean root rot caused by the oomycete Phytophthora sojae is a serious soilborne disease threatening soybean production in China. Bacillus velezensis FZB42 model strain for Gram-positive plant growth-promoting rhizobacteria and able to produce multiple antibiotics. In this study, we demonstrated that B. can efficiently antagonize P. sojae. The underlying mechanism inhibition was then investigated. mutants deficient synthesis of lipopeptides (bacillomycin D fengycin), known have antifungal...

10.1128/aem.01601-21 article EN Applied and Environmental Microbiology 2021-09-22

Ligustri Lucidi Fructus (LLF), the fruit of Ligustrum lucidum Ait. (Oleaceae), has been used as a common herbal medicine in clinical practice China for nearly 2000 years. In most cases, LLF is prescribed decoctions form processed products rather than crude drugs. this study, an ultra-high performance liquid chromatography coupled with electrospray ionization-quadrupole-time flight-mass spectrometry (UHPLC-ESI-Q-TOF-MS) method was established rapid separation and identification multiple...

10.3390/molecules22050689 article EN cc-by Molecules 2017-04-26

Untimely or improper treatment of traumatic bleeding may cause secondary injuries and even death. The traditional hemostatic modes can no longer meet requirements coping with complicated emergencies. With scientific technological advancements, a variety topical materials have been investigated involving inorganic, biological, polysaccharide, carbon-based materials. These their respective merits defects. In this work, the application mechanism major materials, especially some nanomaterials...

10.1021/acsabm.3c01144 article EN ACS Applied Bio Materials 2024-02-19

ABSTRACT Our objectives were to investigate the effect of blanching on nutrients, color, α‐ and β‐carotenes, dietary fiber, water‐holding capacity carrot pulp after juice was extracted. Carrot contained 4‐5% protein, 8‐9% reducing sugars, 5‐6% minerals. Compared color fresh juice, from blanched carrots retained redness values better than that unblanched carrots. Pulp unblanched: 17% blanched: 31‐35% total β carotenes in Glucose galacturonic acid predominant sugars nonstarchy polysaccharides...

10.1111/j.1365-2621.1994.tb14666.x article EN Journal of Food Science 1994-11-01

The pollen of Typha angustifolia L. (Typhaceae) has been used as a traditional Chinese medicine for improving the microcirculation and promoting wound healing. Flavonoids are main constituent in plant, but little is known about antioxidant activity principal detail.To assess activities ethanol water extracts two constituents pollen.Plant material (1 g) was extracted by 95% (10 mL × 2, 1 h each), respectively. (0.8-2.6 mg/mL) were measured DPPH reducing ferric chloride (1.7-2.6 mg/mL)....

10.1080/13880209.2017.1300818 article EN cc-by-nc Pharmaceutical Biology 2017-01-01

<sec> <title>BACKGROUND</title> Early identification and monitoring of preserved ratio impaired spirometry (PRISm) population active intervention can reduce the incidence rate chronic obstructive pulmonary disease (COPD) delay process. However, there is no evidence on best treatments, effectiveness safety pharmacological interventions poor. Traditional Chinese medicine (TCM) has been used to treat COPD for many years. </sec> <title>OBJECTIVE</title> To clarify clinical efficacy Bufei...

10.2196/preprints.71197 preprint EN cc-by 2025-01-12

Tryptophan hydroxylase 1 (Tph-1), the principal enzyme for peripheral serotonin biosynthesis, provides a novel target to design anabolic agents osteoporosis. Here, we present design, synthesis of series ursolic acid derivatives under guidance docking technique, and bioevaluation using RBL2H3 cells ovariectomized (OVX) rats. Of compounds, 9a showed potent inhibitory activity on biosynthesis. Further investigations revealed that 9a, as an efficient Tph-1 binder identified by SPR (estimated KD:...

10.1021/jm5002293 article EN Journal of Medicinal Chemistry 2014-05-20

ABSTRACT Effects of processing variables on color, α‐ and β‐carotenes, non‐starchy polysaccharides (NSP) carrot juice products were investigated. Unblanched‘carrots produced the highest amounts lowest pulp. Compared to color fresh juice, canned from acetic acid‐blanched carrots retained redness best, unblanched least. Juice total carotenes. Retorting, concentrating, freeze‐drying partly reduced product In most cases, various methods greater for β‐carotene than α‐carotene. NSP contents ranged...

10.1111/j.1365-2621.1994.tb14665.x article EN Journal of Food Science 1994-11-01
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