A5006267969- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Urological Disorders and Treatments
- Esophageal Cancer Research and Treatment
- Urinary Bladder and Prostate Research
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Urologic and reproductive health conditions
- Cancer Immunotherapy and Biomarkers
- Epigenetics and DNA Methylation
- Laser-induced spectroscopy and plasma
- Colorectal Cancer Screening and Detection
- Cancer, Lipids, and Metabolism
- Cancer Research and Treatments
- Amino Acid Enzymes and Metabolism
- Cancer survivorship and care
- Urinary Tract Infections Management
- Enhanced Recovery After Surgery
- AI in cancer detection
- Global Cancer Incidence and Screening
- Cardiac, Anesthesia and Surgical Outcomes
- Metabolism, Diabetes, and Cancer
- Pelvic floor disorders treatments
Amsterdam University Medical Centers
2018-2025
University of Amsterdam
2018-2025
Amsterdam UMC Location VUmc
2025
Vrije Universiteit Amsterdam
2023-2024
Cancer Center Amsterdam
2022-2024
Eindhoven University of Technology
2021-2024
Jeroen Bosch Ziekenhuis
2008-2018
Robert Bosch (Germany)
2004-2015
University of Illinois Chicago
2015
Rijnstate Hospital
2013
The combination of radiotherapy plus long-term medical suppression androgens (> or = 2 years) improves overall survival in patients with locally advanced prostate cancer. We compared the use short-term androgen treatment cancer.We randomly assigned cancer who had received external-beam 6 months to two groups, one receive no further (short-term suppression) and other 2.5 years a luteinizing hormone-releasing hormone agonist (long-term suppression). An outcome noninferiority as required hazard...
The objective of this study was to evaluate the role 3-T multiparametric magnetic resonance imaging (MP-MRI) and resonance-guided biopsy (MRGB) in early risk restratification patients on active surveillance at 3 12 months follow-up.Within 4 hospitals participating a large trial, side initiated. Pelvic imaging, prostate MP-MRI, MRGB were performed (latter MP-MRI only) after cancer diagnosis 1 hospitals. Cancer-suspicious regions (CSRs) defined using Prostate Imaging Reporting And Data System...
COMMENTMetabolic syndrome (MetS) results from dietary caloric excess and a sedentary lifestyle requires presence of any three the five metabolic risk factors which are in short obesity, elevated serum trigycerides, reduced high-density lipoprotein-cholestrol, blood pressure fasting glucose.The association between MetS prostate cancer (PCa) has been an area research recent years.Possible mechanisms that implicated for this perturbations cellular signaling systems, derangements circulating...
We aimed to determine whether diffusion-weighted magnetic resonance imaging, by means of the apparent diffusion coefficient (ADC), is able guide resonance-guided biopsy in patients fit for active surveillance (AS) and identify harboring high-grade Gleason components not suitable AS.Our study was approved institutional review board all participating hospitals, signed informed consent at inclusion. Fifty-four consecutive with low-risk prostate cancer (PCa) underwent multiparametric imaging...
To define possible predictive factors for success and complications ureteroscopic holmium laser lithotripsy procedures.All 105 procedures performed between 1996 2005 were analyzed. Data recorded sex, age, stone size, location, complications, rate (stone-free after 3 months), operative time, surgeon experience this procedure. For further analysis, was divided into four groups based on the number of performed. Multivariate analysis used to successful procedures.Total 84.8%. Complications...
Three-dimensional multiparametric ultrasound (3D mpUS) shows promise for accurately diagnosing prostate cancer. However, its technical complexity presents usability challenges. Human Factor Engineering (HFE) studies the interaction between devices and users, by reducing human error, increasing productivity, enhancing safety. The objective is to develop a training program 3D mpUS using HFE (NCT04605276). This study employs human-centered design approach, principle of HFE, with formative...
Muscle-invasive bladder cancer (MIBC) has a poor prognosis. Chemoradiotherapy (CRT) in selected patients comparable results to radical cystectomy. Results of neoadjuvant immune checkpoint inhibitors (ICIs) before cystectomy are promising. We hypothesize that ICI concurrent CRT (iCRT) is safe and may improve treatment outcomes. To determine the safety iCRT for MIBC. This multicenter, phase 1b, open-label, dose-escalation study determined with three regimens nonmetastatic (T2-4aN0-1)...
To determine the relationship of age to side-effects leading discontinuation treatment in patients with stage Ta-T1 non-muscle-invasive bladder cancer (NMIBC) treated maintenance bacille Calmette-Guérin (BCG).We evaluated toxicity for 487 eligible intermediate- or high-risk (without carcinoma situ) NMIBC randomised receive 3 years BCG therapy (247 alone and 240 + isoniazid) European Organisation Research Treatment Cancer Genito-Urinary Group trial 30911. The percentage who stopped number...
Abstract Purpose Urothelial bladder cancer (UCB) care requires frequent follow-up cystoscopy and surgery. Confocal laser endomicroscopy (CLE) is a probe-based optical technique that can provide real-time microscopic evaluation with the potential for outpatient grading of UCB. This study aims to investigate diagnostic accuracy interobserver variability UCB CLE during flexible (fCLE). Methods Participants scheduled transurethral resection papillary tumors were prospectively included...
The best practice for the organization of follow-up care in oncology is under debate, due to growing numbers cancer survivors. Understanding survivors' preferences elementary designing patient-centred care. Based on data from prostate and melanoma survivors, this study aims identify: 1) providers, instance medical specialist, nurse or general practitioner; 2) characteristics associated with these 3) preferred provider discuss cancer-related problems.Survivors diagnosed (N = 535) 232) between...