A5100764323- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Advanced MRI Techniques and Applications
- Radiation Dose and Imaging
- Advanced X-ray and CT Imaging
- Optical Imaging and Spectroscopy Techniques
- Liver Disease Diagnosis and Treatment
- Orthopaedic implants and arthroplasty
- Pancreatic and Hepatic Oncology Research
- Photoacoustic and Ultrasonic Imaging
- Spectroscopy Techniques in Biomedical and Chemical Research
- Cardiac Imaging and Diagnostics
- Lower Extremity Biomechanics and Pathologies
- Hepatocellular Carcinoma Treatment and Prognosis
- Parkinson's Disease Mechanisms and Treatments
- Terahertz technology and applications
- Functional Brain Connectivity Studies
- Liver Diseases and Immunity
- Cancer Immunotherapy and Biomarkers
- Inflammatory Biomarkers in Disease Prognosis
- Cancer, Hypoxia, and Metabolism
- Cancer Risks and Factors
- Renin-Angiotensin System Studies
- Orthopedic Infections and Treatments
- melanin and skin pigmentation
University of Science and Technology Beijing
2024-2025
The First Affiliated Hospital, Sun Yat-sen University
2013-2024
Sun Yat-sen University
2015-2024
Wuhan University
2024
Renmin Hospital of Wuhan University
2024
Xinxiang Medical University
2023-2024
Guizhou Normal University
2024
First Affiliated Hospital of Xinxiang Medical University
2023-2024
Henan Psychiatric Hospital
2024
China Three Gorges University
2023
Arterial levels of shear stress (25 dynes/cm2) can elevate constitutive endothelial nitric oxide synthase (eNOS) gene expression in cultured cells (Ranjan et al., 1995). By PhosphorImaging Northern blots, we report that the eNOS/glyceraldehyde 3-phosphate dehydrogenase (GAPDH) messenger RNA (mRNA) ratio bovine aortic (BAEC) increased by 4.8- and 7.95-fold after 6-hr exposure 4 25 dynes/cm2, respectively. Incubation BAEC with dexamethasone (1 microM) had no effect on induction eNOS mRNA....
Introduction Mercury (Hg) and its organic forms can accumulate in marine organisms, undergoing biomagnification as they transfer through food chains. However, the factors affecting such Hg are not fully understood. Methods This study analyzed of total mercury (THg) methylmercury (MeHg) chains represented by invertebrates fish from offshore waters Changshan Archipelago, grouped into continuous trophic level (TL) ranges based on nitrogen stable isotopic analysis. Results Concentrations THg...
Reactive oxygen species (ROS) are an important factor in the development of skin photodamage after ultraviolet A (UVA) radiation. flavonoid antioxidant, baicalin, can selectively neutralize super-oxide anion (O(2)(-)) while having no significant effect on (•)OH. Fibroblasts a key component dermis. In present study, we investigated protective effects baicalin human fibroblasts (HSFs) under UVA induced oxidative stress. Fluorescence microscopy and flow cytometry were used to assay...
Background Functional near-infrared spectroscopy (fNIRS) identifies neurophysiological differences between psychiatric disorders by assessing cortical hemodynamic function. Few trials have studied in brain functional activity first-episode medication-naïve depression patients (FMD) and recurrent major (RMD). We aimed to determine the FMD RMD oxygenated hemoglobin concentration ([oxy-Hb]), investigate correlation frontotemporal cortex activation clinical symptoms. Methods recruited 40 with...
Epithelial-mesenchymal transition (EMT) is critical for cancer cell metastasis. Recently, EMT was reported to be associated with the inflammatory tumour microenvironment and, therefore, might a predictive biomarker immune checkpoint blockade agents. However, underlying mechanism still unclear. Patient survival data our HCC cohort, TCGA and GEO datasets were determined by Kaplan-Meier analysis. The functional roles of ELMO1 in demonstrated series vitro vivo experiments. Gene microarray...
Purpose Various inflammation-based prognostic biomarkers such as the platelet to lymphocyte ratio and neutrophil ratio, are related poor survival in patients with intrahepatic cholangiocarcinoma (ICC). This study aims investigate value of aspartate aminotransferase index (ANRI) ICC after hepatic resection. Materials Methods Data 184 hepatectomy were retrospectively reviewed. The cut-off ANRIwas determined by a receiver operating characteristic curve. Preoperative ANRI clinicopathological...
Objective: Obeticholic acid (OCA), a potent farnesoid X receptor (FXR) agonist, is promising drug for nonalcoholic fatty liver disease (NAFLD); however, it can cause injury, especially at high doses. Here, we investigated the role of FXR in high-dose OCA-induced hepatoxicity condition NAFLD mouse model. Methods: Wild-type (WT) mice and FXR-/- were administered with over-dose OCA (0.40%) (0.16%), high-fat diet. RNA-seq on samples fed was performed to dig out prominent biological events...
Besides the roles in regulating immune responses, recent studies have also suggested a pivotal role of Toll-like receptors (TLRs) lipid metabolism. Previously we reported that graphene oxide (GO) suppresses TLR signaling pathways. In this study, further investigated vivo toxicity GO zebrafish larvae via TLRs. Zebrafish embryos (5 h post fertilization; hpf) were exposed to 0.01, 0.1, 1 or 10 mg/L for up 5 days, and results revealed induced developmental toxicity, form delayed hatching time...
Previous criteria had limited value in early diagnosis of periprosthetic joint infection (PJI). Here, we constructed a novel machine learning (ML)-derived, "in-time" diagnostic system for PJI and proved its validity.
The aim of the present study was to investigate application a double‑echo pulse sequence with 3D ultrashort echo time (UTE) in magnetic resonance imaging (MRI) bones and joints. In total, 7 healthy volunteers 1 volunteer suspected tear lateral meniscus left knee joint underwent MRI UTE. performed on tibial diaphysis, ankle segment porcine fibula vitro. (TE1) UTE images for achilles tendon were set as 0.08, 0.16, 0.24 0.35 msec. maximum intensity projection (MIP) difference created from...
To investigate the late effects of radiation on child-bearing women, a follow-up study was performed 39-year-old survivor 16 years after (60)Co accident. The woman, Fang, 19 weeks pregnant at time exposure. Physical examinations, full range clinical laboratory and imaging tests, as well cytogenetic analyses were conducted to evaluate Fang's current health conditions. Fang shows appearance premature ageing has decreased menstrual period. Laboratory studies tests suggest nodular goitre disease...