A5034087947- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Gynecological conditions and treatments
- Intestinal and Peritoneal Adhesions
- Intraperitoneal and Appendiceal Malignancies
- Pelvic and Acetabular Injuries
- Pelvic floor disorders treatments
- Colorectal Cancer Surgical Treatments
- Cervical Cancer and HPV Research
- Reproductive System and Pregnancy
- Hernia repair and management
- Ureteral procedures and complications
- Pregnancy-related medical research
- Sarcoma Diagnosis and Treatment
- Anorectal Disease Treatments and Outcomes
- Colorectal and Anal Carcinomas
- COVID-19 and healthcare impacts
- Cancer-related molecular mechanisms research
- Minimally Invasive Surgical Techniques
- Renal cell carcinoma treatment
- Pancreatic and Hepatic Oncology Research
- MicroRNA in disease regulation
- Maternal and fetal healthcare
Ospedale Sacro Cuore Don Calabria
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2024
Istituto Superiore di Sanità
2023
Bocconi University
2023
Policlinico Umberto I
2022
Sapienza University of Rome
2022
University of Verona
2010-2022
Ospedale Policlinico San Martino
2022
University of Genoa
2022
Riga East University Hospital
2020
Endometriosis is a benign, chronic, inflammatory condition affecting up to 10 % of women and characterised by the presence glands stroma tissue outside uterus. Epidemiological clinical studies demonstrate consistent association between endometriosis infertility. However, this relationship far be clearly understood several mechanisms are involved. Available data show that patients with have an increased estimated risk infertility two four times compared general population. On other hand,...
In Brief OBJECTIVE: To investigate the risk of vaginal cuff dehiscence after different routes hysterectomy and methods closure. METHODS: A multi-institutional analysis 12,398 patients who underwent for both benign malignant disease between 1994 2008 was performed. We analyzed how approaches to suture may influence development dehiscence. RESULTS: Women had total laparoscopic (n=3,573), abdominal (n=4,291), (n=4,534) hysterectomies experienced 23 (0.64%), 9 (0.2%), 6 (0.13%) cases dehiscence,...
The aim of our study was to define tissue and plasma miRNA signatures, which could potentially serve as diagnostic prognostic markers in endometrioid endometrial cancer (EEC) investigate profiles regard clinicopathological characteristics. Tissue samples were collected from 122 women (77 EEC 45 controls). Expression profiling 866 human miRNAs 89 viral performed 24 followed by qPCR validation 104 patients. 16 analyzed 48 samples. Microarray revealed regulation 21 tissues comparing normal...
The purpose of the study was to determine influence bowel endometriosis on fertility, and whether its removal improves fecundity in women with endometriosis-associated infertility.Three groups infertile patients were included study. Group A (60 women) consisted who underwent surgery for colorectal segmental resection. In group B, 40 evidence without C 55 moderate or severe at least one endometrioma deep infiltrating but involvement. clinically evaluated before laparoscopy then 1 month, 6...
Alterations of mTOR gene expression have been implicated in the pathogenesis endometrioid endometrial cancer however only few studies explored cause increased activation this malignancy. miRNAs are small, noncoding RNAs, which were proven to regulated at posttranscriptional level. The study aimed explore deregulation targeting kinase (miR-99a, miR-100 and miR-199b) as a possible its altered EEC tissues. In addition three was investigated plasma patients assessed terms diagnostic prognostic...
To evaluate the diagnostic accuracy of transvaginal ultrasound (TVS) in predicting deep endometriosis (DE) following International Deep Endometriosis Analysis (IDEA) consensus methodology.This was an international multicenter prospective study involving eight centers across six countries (August 2018-November 2019). Consecutive participants with suspected based on clinical symptoms or historical diagnosis were included. The index test TVS performed preoperatively accordance IDEA statement....
BACKGROUND: Little is known about the morbidity associated with laparoscopic complete excision of endometriosis in terms urinary, digestive and sexual function. METHODS: We performed a prospective non-randomized study 45 patients all detectable foci segmental bowel resection using non nerve-sparing technique (control group–group A n = 20) (case B 25). At initial gynaecological evaluation, at follow-up details on dysmenorrhoea, pelvic pain, dyspareunia dyschezia were evaluated an...
<h3>Objective</h3> This study aimed to analyze the prognostic factors for overall and progression-free survival in patients with vulvar cancer. <h3>Methods</h3> international, multicenter, retrospective included 2453 diagnosed cancer at 100 different institutions. Inclusion criteria were institutional review board approval from each collaborating center, pathologic diagnosis of invasive carcinoma vulva, primary treatment performed participating center. Patients intraepithelial neoplasia or...
ObjectiveTo study the ultrasonographic diagnostic accuracy and characteristics of parametrial endometriosis comprehensively.DesignThis prospective enrolled patients with suspected deep (DE) scheduled for laparoscopic surgical treatment. Preoperative examinations were performed following International Deep Endometriosis Analysis criteria. This aimed to evaluate presence its characteristics, using diagnosis as reference standard. Additionally, indirect signs DE concomitant nodules associated...