Viesturs Liguts
- Poisoning and overdose treatments
- Forensic Toxicology and Drug Analysis
- Psychedelics and Drug Studies
- Cannabis and Cannabinoid Research
- Renal function and acid-base balance
- Drug-Induced Hepatotoxicity and Protection
- Neuroscience of respiration and sleep
- Methemoglobinemia and Tumor Lysis Syndrome
Riga East University Hospital
2020-2024
Riga Stradiņš University
2022
Introduction Cannabis is the most common recreational drug worldwide and synthetic cannabinoid receptor agonists are currently largest group of new psychoactive substances. The aim this study was to compare clinical features outcomes lone acute cannabis toxicity with agonist in a large series presentations European emergency departments between 2013-2020.
This study hypothesized that 3,4-methylenedioxymetamfetamine intoxication presents with distinct clinical features and outcomes when combined other substances of misuse, compared to mono-3,4-methylenedioxymetamfetamine intoxication. investigated the presentation acute intoxication, exclusive co-usage ethanol, 3,4-methylenedioxymetamfetamine-co-intoxication or without a focus on patient sex differences. A retrospective analysis was conducted using Euro-DEN Plus database (2013-2022), which...
Novel psychoactive substances (NPS) have been increasingly reported in the last 15-20 years. We aimed to describe presentations emergency department (ED) with acute recreational drug toxicity involving NPS.Data were extracted from European Drug Emergencies Network (Euro-DEN) Plus database for all ED (36 EDs 24 countries) between January 2014 and December 2019. Patient demographics, agents involved, clinical outcomes described subgroup of NPS was compared rest cohort.Out 43,633 Euro-DEN...
Context 3,4-Methylenedioxymethamphetamine (MDMA) remains one of the most commonly used recreational drugs in Europe. Monitoring Emergency Department (ED) presentations with acute toxicity associated MDMA is important to determine trends use and harms.Methods Data were extracted from European Drug Emergencies Network (Euro-DEN) Plus database for all ED involving use, alone or combination other substances, between 1 January 2014 31 December 2017. Geographical distribution, time trends, patient...
Ethylene glycol is a sweet-tasting toxic alcohol contained in variety of chemical preparations. In patients poisoned with ethylene glycol, diagnosis often based upon clinical suspicion and nonspecific tests. Hypocalcemia present due to calcium oxalate crystals formed by oxalic acid metabolite complexation. This retrospective study involved review records poisoning. Results blood gas samples, lactate, ionized calcium, serum creatinine were documented compared between various groups. The...
Ethylene glycol is a toxic alcohol that occurs in variety of chemical preparations. In patients poisoned with ethylene glycol, diagnosis usually based on clinical suspicion and non-specific tests. Hypocalcaemia often present results from production calcium oxalate crystals oxalic acid. 
 Assess whether reduction ionized concentration common finding poisoning, it can be appropriate additional marker for the prognosis outcome.
 Retrospective records review poisoning at Riga East...