A5103268681- Poisoning and overdose treatments
- Opioid Use Disorder Treatment
- Forensic Toxicology and Drug Analysis
- Cardiac Arrest and Resuscitation
- Cannabis and Cannabinoid Research
- Emergency and Acute Care Studies
- Alcoholism and Thiamine Deficiency
- Injury Epidemiology and Prevention
- Substance Abuse Treatment and Outcomes
- Clinical Reasoning and Diagnostic Skills
- Prenatal Substance Exposure Effects
- Sepsis Diagnosis and Treatment
- Disaster Response and Management
- Homelessness and Social Issues
- Suicide and Self-Harm Studies
- Ultrasound in Clinical Applications
- Trauma and Emergency Care Studies
- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Anesthesia and Pain Management
- Viral Infections and Outbreaks Research
- Schizophrenia research and treatment
- Pediatric Pain Management Techniques
- COVID-19 and healthcare impacts
- Phonocardiography and Auscultation Techniques
Oslo University Hospital
2008-2024
University of Oslo
2011-2024
Stiftelsen Norsk Luftambulanse
2019-2024
Nasjonalforeningen for Folkehelsen
2024
Norwegian Medical Association
2024
Ullevål Sykehusapotek
2012
Institutt for Eksperimentell Medisinsk Forskning
2011
Norwegian Directorate of Health
2010
Haukeland University Hospital
2010
St Olav's University Hospital
2010
Introduction Cannabis is the most common recreational drug worldwide and synthetic cannabinoid receptor agonists are currently largest group of new psychoactive substances. The aim this study was to compare clinical features outcomes lone acute cannabis toxicity with agonist in a large series presentations European emergency departments between 2013-2020.
Abstract Aims To measure and evaluate clinical response to nasal naloxone in opioid overdoses the pre‐hospital environment. Design Randomised, controlled, double‐dummy, blinded, non‐inferiority trial, conducted at two centres. Setting Participants were included by ambulance staff Oslo Trondheim, Norway, treated place where overdose occurred. Men women age above 18 years with miosis, rate of respiration ≤8/min, Glasgow Coma Score <12/15 included. Informed consent was obtained through a...
The changing pattern of acute poisoning may affect complications and outcome in these patients. An update study on poisonings was therefore performed compared to similar data from 1980.A prospective cross-sectional multi-center all adult patients (> or = 16 years) hospitalized Oslo with a main diagnosis poisoning, irrespective intention, over one-year period.Of 947 admissions, 222 (23%) were comatose. Complications observed 173 (18%), slightly reduced 1980 (22%). Ten (1.1%) died six (0.6%)...
This study aimed to characterize patients admitted critical care following Emergency Department (ED) presentation with acute recreational drug toxicity and identify determinants of admission care. A retrospective multicenter matched case-control was conducted by the European Drug Network Plus (Euro-DEN Plus) over period 2014–2021. The cases were ED presentations care, controls consisted medically discharged directly from ED. potential assessed through multivariable conditional stepwise...
Acute poisonings may require identification of the toxic agents. It is impossible for routine laboratories to provide a full spectrum toxicological analyses, and clinicians should know reliability clinical diagnoses We performed 1-year study hospitalized acute determine agreement between assessment on admission serum laboratory tests eight common Blood samples were drawn in 665 (70%) 947 admissions. The total number found agents (967) exceeded clinically suspected (871) by 11%. analyses was...
To develop a general and internationally applicable template of data variables for reporting interhospital neonatal intensive care transports.
Abstract Aim This initial Norwegian study aimed to quantify the vibrations and sounds experienced by neonates when they were transported helicopter in an incubator. Methods Two neonatal manikins weighing 500 2000 g placed a transport incubator Airbus H145 D3 during standard flight profiles. The measured on mattress inside sound levels outside Results highest vibration recorded profiles lighter manikin was used. These ranged 0.27–0.94 m/s 2 , compared 0.27–0.76 for heavier manikin....
Context 3,4-Methylenedioxymethamphetamine (MDMA) remains one of the most commonly used recreational drugs in Europe. Monitoring Emergency Department (ED) presentations with acute toxicity associated MDMA is important to determine trends use and harms.Methods Data were extracted from European Drug Emergencies Network (Euro-DEN) Plus database for all ED involving use, alone or combination other substances, between 1 January 2014 31 December 2017. Geographical distribution, time trends, patient...
Background and importance Patients who use recreational drugs frequently co-ingest ethanol, which is considered a central nervous system (CNS) depressant. The clinical relevance of this in acute toxicity involving other CNS depressants not well described. Objective To assess the impact ethanol co-use patients presenting to emergency department (ED) with depressant drugs. Design, settings participants A retrospective multicentre study using data from Euro-DEN Plus database January 2014...
Background: Although the United States and numerous other countries are amidst an opioid overdose crisis, access to safe injection facilities remains limited. Methods: We used prospective data from ambulance journals in Oslo, Norway, describe patterns, severity, outcomes of overdoses compared these characteristics among various locations. also examined what role a facility may have had on overdoses. Results: Based 48,825 calls, 1054 were for 465 individuals during 2014 2015. The rate calls...
To investigate whether the severity of acute recreation drug toxicity presentations to emergency departments (EDs) in Europe has changed recent years and uncover potential sex differences.We analysed 36 EDs 24 European countries relating recreational toxicity, with separate analysis for involving lone use cannabis, cocaine, heroin. As markers, we calculated rates hospitalization, admission ICU, intubation, death by annual quarters between 2014 2019. Trends on over time were estimated...
Female drug users report poorer physical and mental health than male users. We describe female patients treated for acute recreational toxicity, look gender differences in clinical state, treatment, toxic agents taken.
Abstract Background Amidst the ongoing opioid crisis there are debates regarding optimal route of administration and dosages naloxone. This applies both for lay people emergency medical services, in development new naloxone products. We examined characteristics administration, including predictors multiple doses during patient treatment by service staff order to enlighten this debate. Methods was a prospective observational study patients administered Oslo City Center service, Norway...
The cohort of critically ill patients transported between Intensive Care Units (ICUs) in Norway has not been studied previously. aim this study was to describe the characteristics and transports for different types interhospital transfers explore whether there were differences morbidity mortality transfer categories general Norwegian ICU population.All adult transferred two geographically during a one-year period registered. Patient transport data obtained from Registry, Cause Death hospital...
Pain management can be challenging, especially in remote locations where first responders are not certified health care personnel. In these settings, traditional intravenous administration of analgesics is feasible. this study, we explore the feasibility using methoxyflurane as a first-line analgesic ski-related traumas, administered by ski patrol, acting municipality physician's aiding This quality assessment project aimed at improving pain trauma patients largest resort Norway. Members...
Abstract Gas chromatographic analysis for quantification of plasma methanol requires laboratory equipment and personnel, it is typically unavailable in short time notice, especially low‐ middle‐income countries. Detection formate with the enzyme oxidase (FOX) a promising method that can make diagnosis poisoning simple fast. The aims this study were to test sensitivity specificity modified FOX‐enzyme point‐of‐care (POC)‐model containing samples from patients metabolic acidosis. aqueous...
Abstract Background Pre-hospital pain management has traditionally been performed with intravenous (IV) morphine, but oligoanalgesia remain a recognized problem. Pain reduction is essential for patient satisfaction and regarded as measure of successful treatment. We aim to establish whether non-invasive methods such inhalation methoxyflurane non-inferior intranasal fentanyl or the well-known IV morphine in pre-hospital treatment acute pain. Method/design The PreMeFen study phase three,...
Each year, nearly 100 deaths and more than 10,000 admissions to Norwegian hospitals can be attributed acute poisoning from non-medical substances drugs in supra-therapeutic doses. The aim of this study was evaluate hospitals' routines for coding provide information on the toxic agents involved.Medical records (at 6 period 1.1.1999 -31.12.2005) due were re-examined assess accuracy diagnosis codes.Acute registered as cause 225 period. re-evaluation concluded that 45 these had other causes. In...
Alcohol and drug abuse are potentially modifiable risk factors for critical illness. The aims of this study were to describe patients with substance abuse-related admissions (abbreviated SARA) in a mixed intensive care (ICU) population Oslo, compare these non-SARA.Cross-sectional prospective medical surgical ICU-population Norway. Data collected consecutively using questionnaire, records, toxicology results. SARA included due acute or chronic complications alcohol abuse, as well injuries.Of...
Self-discharge is a risk factor for readmission and excess mortality. We assess the rate of self-discharge from emergency department (ED) among presentations acute recreational drug toxicity identify factors associated with self-discharge.From Euro-DEN Plus database to ED toxicity, we extracted data 11 centres in seven European countries 2014 2017. was defined as taking one's own discharge or escaping before being medically cleared. used multiple logistic regression analyses look...
Evaluation of ICU services are challenging due to variations in ICU-beds availability and case-mix different intensive care populations. The selection patients may also vary between local regional hospitals these differences important address when studying patients. Patients with medical surgical admissions often treated specialized ICUs have needs. Thus, separate description be useful the planning future treatment.