A5043379709- Poisoning and overdose treatments
- Forensic Toxicology and Drug Analysis
- Acute Myocardial Infarction Research
- Emergency and Acute Care Studies
- Opioid Use Disorder Treatment
- Healthcare Decision-Making and Restraints
- Migration, Health and Trauma
- Cannabis and Cannabinoid Research
- Psychedelics and Drug Studies
- Alcoholism and Thiamine Deficiency
- Suicide and Self-Harm Studies
- Homelessness and Social Issues
- Heart Failure Treatment and Management
- Healthcare cost, quality, practices
- Substance Abuse Treatment and Outcomes
- Innovations in Medical Education
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Clinical Reasoning and Diagnostic Skills
- European and International Law Studies
- Global Maternal and Child Health
- Restraint-Related Deaths
- Schizophrenia research and treatment
- Sepsis Diagnosis and Treatment
- Pharmacovigilance and Adverse Drug Reactions
University of Oslo
2016-2025
Norwegian Medicines Agency
2009-2022
657 Oslo
2021
Institutt for Eksperimentell Medisinsk Forskning
2015-2020
Oslo Kommune
2015-2020
Psychosis can be associated with acute recreational drug and novel psychoactive substance (NPS) toxicity. However, there is limited data available on how common this which drugs are most frequently implicated. We describe a European case series of psychosis toxicity, estimate the frequency for different drugs.
Introduction Cannabis is the most common recreational drug worldwide and synthetic cannabinoid receptor agonists are currently largest group of new psychoactive substances. The aim this study was to compare clinical features outcomes lone acute cannabis toxicity with agonist in a large series presentations European emergency departments between 2013-2020.
Most patients with acute poisoning are treated as outpatients worldwide. In Oslo, these in a physician-led outpatient clinic limited diagnostic and treatment resources, which reduces both the costs emergency department overcrowding. We describe patterns, treatment, mortality, factors associated hospitalization follow-up at this Emergency Medical Agency (EMA, "Oslo Legevakt"), we evaluate safety of current practice. All poisonings adults (> or = 16 years) EMA during one year (April 2008 to...
Irregular legal status is a recognized health risk factor in the context of migration. However, undocumented migrants are rarely included surveys and register studies. Adverse perinatal outcomes especially important because they have long-term consequences societal factors modifiable. In this study, we compare to foreign-born Norwegian-born residents, using population-based register.
Introduction: Studies report a high variability of cognitive impairment in people who use drugs, ranging from 20% to 80%. Most research focus on individuals drugs are either admitted treatment facilities or incarcerated and being abstinent substances. The present study aimed assess function among populations with ongoing, severe, habitual substance use, mimicking real-world day-to-day situation. Methods: Cross-sectional design 171 participants (70.2% male) severe recruited two sites Oslo,...
Acute chest pain has a high hospital referral rate due to the limited ability exclude acute myocardial infarction (MI) in primary care. We aimed evaluate effectiveness of implementing European Society Cardiology (ESC) 0/1-hour algorithm for high-sensitivity cardiac troponin T (hs-cTnT) testing emergency In prospective study (April-October 2023), ESC hs-cTnT was implemented at main care clinic Oslo, Norway. All consecutive patients ≥ 18 years with non-traumatic having measurements done were...
Migrants are known to have an increased risk for adverse complications during delivery. However, it is not whether undocumented migrants a different profile compared documented and non-migrants. Better knowledge about migrants' reproductive outcomes crucial enable targeted preventive interventions. We performed historical register-based population study based on numbers from the Medical Birth Registry of Norway (MBRN) 1999 2020. Women aged 18-49 years with singleton births were included, in...
Introduction Novel point-of-care (POC) high-sensitivity cardiac troponin (hs-cTn) tests could enhance acute myocardial infarction (MI) assessment outside hospital. This pilot study evaluates the efficacy, feasibility, and precision of QuidelOrtho TriageTrue hs-cTnI POC assay when used by non-laboratory personnel in emergency primary care. Methods A prospective was conducted from April to June 2024 at main care clinic Oslo, Norway. Patients ≥18 years with non-traumatic chest pain were...
This study hypothesized that 3,4-methylenedioxymetamfetamine intoxication presents with distinct clinical features and outcomes when combined other substances of misuse, compared to mono-3,4-methylenedioxymetamfetamine intoxication. investigated the presentation acute intoxication, exclusive co-usage ethanol, 3,4-methylenedioxymetamfetamine-co-intoxication or without a focus on patient sex differences. A retrospective analysis was conducted using Euro-DEN Plus database (2013-2022), which...
Context: Recreational drug toxicity is frequent. Availability of new psychoactive substances steadily increasing. However, data with verified analyses from clinical settings are limited. To evaluate the impact novel (NPS) on recreational in Oslo, Norway, we analysed samples a selection patients.Methods: All patients presenting at Oslo Accident and Emergency Outpatient Clinic (OAEOC) University Hospital (OUH) were registered April through September 2014. Oral fluid collected OAEOC. Blood OUH....
In Oslo, the majority of patients with acute poisoning are treated in primary care, at an emergency outpatient clinic limited diagnostic and treatment resources. We describe poisonings currently seen this setting. compare our findings previous studies, special concern for appearance new toxic agents, changes overall numbers patterns poisoning. Observational study. Patients above age 12 years presenting Oslo Accident Emergency Outpatient Clinic (Oslo Legevakt) were included consecutively from...
To analyse the relative percentage of acute recreational drug toxicity emergency department (ED) presentations involving main groups according to age and sex investigate different patterns based on strata.We analysed all patients with included by Euro-DEN Plus dataset (22 EDs in 14 European countries) between October 2013 December 2016 (39 months). Drugs were grouped as: opioids, cocaine, cannabis, amphetamines, gamma-hydroxybutyrate (GHB), hallucinogens, new psychoactive substances (NPS),...
Novel psychoactive substances (NPS) have been increasingly reported in the last 15-20 years. We aimed to describe presentations emergency department (ED) with acute recreational drug toxicity involving NPS.Data were extracted from European Drug Emergencies Network (Euro-DEN) Plus database for all ED (36 EDs 24 countries) between January 2014 and December 2019. Patient demographics, agents involved, clinical outcomes described subgroup of NPS was compared rest cohort.Out 43,633 Euro-DEN...
This study aimed to characterize patients admitted critical care following Emergency Department (ED) presentation with acute recreational drug toxicity and identify determinants of admission care. A retrospective multicenter matched case-control was conducted by the European Drug Network Plus (Euro-DEN Plus) over period 2014–2021. The cases were ED presentations care, controls consisted medically discharged directly from ED. potential assessed through multivariable conditional stepwise...
Aims: Despite the excess mortality and morbidity associated with acute poisoning by substances of abuse, follow-up is frequently not organised. We assessed morbidity, including repeated poisoning, after abuse through charting contacts health services. also charted short-term mortality. Methods: Patients 12 years older treated for at a primary care emergency outpatient clinic in Oslo, Norway, were included consecutively from October 2011 September 2012. retrieved information national...
Procedures for the clinical assessment of acute poisoning by substances abuse should identify patients in need hospital admission and avoid hazardous discharges, while keeping observation time short. We assess safety a systematic procedure developed at Oslo Accident Emergency Outpatient Clinic (OAEOC). All 12 years older treated OAEOC were included consecutively from October 2011 to September 2012. Data collected on pre-set registration forms. Information re-presentations health services...
Context 3,4-Methylenedioxymethamphetamine (MDMA) remains one of the most commonly used recreational drugs in Europe. Monitoring Emergency Department (ED) presentations with acute toxicity associated MDMA is important to determine trends use and harms.Methods Data were extracted from European Drug Emergencies Network (Euro-DEN) Plus database for all ED involving use, alone or combination other substances, between 1 January 2014 31 December 2017. Geographical distribution, time trends, patient...
Abstract Aims Hospital admissions of patients with chest pain considered as low risk for acute coronary syndrome contribute to increased costs and crowding in the emergency departments. This study aims estimate cost-effectiveness assessing these a primary care setting, using European Society Cardiology (ESC) 0/1-h algorithm high-sensitivity cardiac troponin T, compared routine hospital management. Methods A analysis was conducted. For estimates, health expenditure from observational OUT-ACS...
Background and importance Patients who use recreational drugs frequently co-ingest ethanol, which is considered a central nervous system (CNS) depressant. The clinical relevance of this in acute toxicity involving other CNS depressants not well described. Objective To assess the impact ethanol co-use patients presenting to emergency department (ED) with depressant drugs. Design, settings participants A retrospective multicentre study using data from Euro-DEN Plus database January 2014...
An epidemic of scopolamine poisonings occurred in Oslo 2008 among users illicit drugs, caused by fake Rohypnol pills. The clinical features, diagnostic process, and handling the are presented.Suspected cases poisoning were extracted reviewing registration forms from an ongoing prospective study acute Oslo. Medical records contacts examined included according to specified criteria.Forty-four probable registered. Main features mydriasis, visual hallucinations, plucking behavior, agitation,...
In 2011 Norway granted undocumented women the right to antenatal care and give birth at a hospital but did not include them in general practitioner reimbursement schemes. As response limited access health care, Non-Governmental Organizations (NGO) have been running clinics for migrants Norway's two largest cities. To further facilitate universal coverage, there is need investigate how pregnant use NGO this affects their maternal health. We therefore investigated received, occurrence of...