- Cardiovascular and exercise physiology
- Heart Rate Variability and Autonomic Control
- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Exercise and Physiological Responses
- COVID-19 and healthcare impacts
- Public Health and Environmental Issues
- Muscle metabolism and nutrition
- High Altitude and Hypoxia
- Emergency and Acute Care Studies
- Statistical and numerical algorithms
- Cardiac Arrest and Resuscitation
- Thermoregulation and physiological responses
- COVID-19 Clinical Research Studies
- Birth, Development, and Health
- Cardiovascular Effects of Exercise
- Heart rate and cardiovascular health
- Hemodynamic Monitoring and Therapy
- Traumatic Brain Injury and Neurovascular Disturbances
- Heart Failure Treatment and Management
- Nutritional Studies and Diet
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Chronic Disease Management Strategies
- Blood Pressure and Hypertension Studies
- Mangiferin and Mango Extracts
Universitat de Barcelona
2020-2024
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2024
Hospital Clínic de Barcelona
2024
Universidad de Las Palmas de Gran Canaria
2015-2021
Hospital Universitario Insular de Gran Canaria
2015-2017
Key points At the end of an incremental exercise to exhaustion a large functional reserve remains in muscles generate power, even at levels far above power output which task failure occurs, regardless inspiratory O 2 pressure during exercise. Exhaustion (task failure) is not due lactate accumulation and associated muscle acidification; neither aerobic energy pathways nor glycolysis are blocked exhaustion. Muscle may actually facilitate early recovery after exhaustive under ischaemic...
Cerebral blood flow (CBF) is regulated to secure brain O 2 delivery while simultaneously avoiding hyperperfusion; however, both requisites may conflict during sprint exercise. To determine whether or CBF prioritized, young men performed exercise in normoxia and hypoxia (P I = 73 mmHg). During the sprints, cardiac output increased ∼22 L min −1 , mean arterial pressure ∼131 mmHg peak systolic ranged between 200 304 mmHg. Middle-cerebral artery velocity (MCAv) values (∼16%) after 7.5 s...
The natural polyphenols mangiferin and luteolin have free radical-scavenging properties, induce the antioxidant gene program down-regulate expression of superoxide-producing enzymes. However, effects these two on exercise capacity remains mostly unknown. To determine whether a combination (peanut husk extract containing 95% luteolin, PHE) (mango leave (MLE), Zynamite®) at low (PHE: 50 mg/day; 140 mg/day MLE 100 mg mangiferin; L) high doses MLE: 420 H) may enhance performance, twelve...
This study hypothesized that 3,4-methylenedioxymetamfetamine intoxication presents with distinct clinical features and outcomes when combined other substances of misuse, compared to mono-3,4-methylenedioxymetamfetamine intoxication. investigated the presentation acute intoxication, exclusive co-usage ethanol, 3,4-methylenedioxymetamfetamine-co-intoxication or without a focus on patient sex differences. A retrospective analysis was conducted using Euro-DEN Plus database (2013-2022), which...
No consensus exists on how to average data optimize V˙ O2max assessment. Although the value is reduced with larger averaging blocks, no mathematical procedure available account for effect of length block O2max. AIMS: To determine that number breaths or seconds included in has and its reproducibility develop correction equations standardize values obtained different strategies.Eighty-four subjects performed duplicate incremental tests exhaustion (IE) cycle ergometer and/or treadmill using two...
While the indication for noninvasive ventilation (NIV) in severely hypoxemic patients with acute heart failure (AHF) is often indicated and may improve clinical course, benefit of early initiation before patient arrival to emergency department (ED) remains unknown.
It remains unknown whether polyphenols such as luteolin (Lut), mangiferin and quercetin (Q) have ergogenic effects during repeated all-out prolonged sprints. Here we tested the effect of Mangifera indica L. leaf extract (MLE) rich in (Zynamite®) administered with either tiger nut (TNE), or (Lut) on sprint performance recovery from ischemia-reperfusion. Thirty young volunteers were randomly assigned to three treatments 48 h before exercise. Treatment A: placebo (500 mg maltodextrin/day); B:...
The purpose of this investigation was to determine whether differences in body composition, pharmacological treatment, and physical activity explain the increased resting metabolic rate (RMR) impaired insulin sensitivity hypertension. Resting blood pressure, RMR (indirect calorimetry), composition (dual‐energy X‐ray absorptiometry), (accelerometry), maximal oxygen uptake (VO 2 max) (ergospirometry), (Matsuda index) were measured 174 patients (88 men 86 women; 20–68 years) with overweight or...
The study aimed to determine the levels of skeletal muscle angiotensin-converting enzyme 2 (ACE2, SARS-CoV-2 receptor) protein expression in men and women assess whether ACE2 is associated with cardiorespiratory fitness adiposity. level vastus lateralis biopsies collected previous studies from 170 (age: 19-65 years, weight: 56-137 kg, BMI: 23-44) 69 18-55 41-126 22-39) was analyzed duplicate by western blot. VO2 max determined ergospirometry body composition DXA. 1.8-fold higher than (p =...
To determine the accuracy and precision of constant infusion transpulmonary thermodilution cardiac output (CITT-Q) assessment during exercise in humans, using indocyanine green (ICG) dilution bolus (BTD) as reference methods, (Q) was determined at rest incremental one- two-legged pedaling on a cycle ergometer, combined arm cranking with leg to exhaustion 15 healthy men. Continuous infusions iced saline femoral vein (n = 41) or simultaneously axillary 66) veins determination temperature...
This study aimed to determine whether the measured resting energy expenditure (REE) in overweight and obese patients living a temperate climate is lower than predicted REE; ascertain which equation should be used climate. REE (indirect calorimetry) body composition (DXA) were 174 (88 men 86 women; 20-68 years old) with or obesity (BMI 27-45 kg m-2). All volunteers residents Gran Canaria (monthly temperatures: 18-24 °C). was by most equations our population. Age BMI similar both sexes. In...
Abstract Hypertension in obese and overweight patients is associated with an elevated resting metabolic rate (RMR). The aim of this study was to determine whether RMR reduced hypertensive treated angiotensin‐converting enzyme inhibitors (ACEI) blockers (ARB). determined by indirect calorimetry 174 volunteers; 93 (46.5 %) were hypertensive, which 16 men 13 women ACEI/ARB, while 30 19 untreated hypertension served as a control group. Treated hypertensives had similar age, BMI, physical...