A5082148865- Antifungal resistance and susceptibility
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Respiratory viral infections research
- Fungal Infections and Studies
- Neutropenia and Cancer Infections
- Nosocomial Infections in ICU
- Electrolyte and hormonal disorders
- COVID-19 and healthcare impacts
- Sarcoidosis and Beryllium Toxicity Research
- Clostridium difficile and Clostridium perfringens research
- Health Systems, Economic Evaluations, Quality of Life
- Antibiotics Pharmacokinetics and Efficacy
- Infection Control and Ventilation
- Lung Cancer Diagnosis and Treatment
- Pneumonia and Respiratory Infections
- Thermal Regulation in Medicine
- Adrenal Hormones and Disorders
- COVID-19 and Mental Health
- Pharmacological Effects and Toxicity Studies
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Dermatological and COVID-19 studies
- Pharmaceutical studies and practices
Medical University of Vienna
2018-2025
University of Massachusetts Chan Medical School
2022
UMass Memorial Medical Center
2022
Background Photon-counting detector (PCD) CT enables ultra-high-resolution lung imaging and may shed light on morphologic correlates of persistent symptoms after COVID-19. Purpose To compare PCD with energy-integrating (EID) for noninvasive assessment post-COVID-19 abnormalities. Materials Methods For this prospective study, adult participants one or more COVID-19-related persisting (resting exertional dyspnea, cough, fatigue) underwent same-day EID between April 2022 June 2022. The 1.0-mm...
Abstract Background Despite advances in antifungals, Candida infections still have a high mortality rate of up to 40%. The ECMM III study Europe investigated the changing epidemiology and outcomes, highlighting need understand manage these infections. Methods In this observational cohort study, participating hospitals enrolled first ten consecutive adults with confirmed candidemia. Data collected included patient demographics, risk factors, hospital stay length (with 90-day follow-up),...
Background/Objectives: Bronchial wash for microbiological cultivation and/or multiplex polymerase chain reaction (PCR) is often routinely performed during bronchoscopy independent of the indication bronchoscopy. This study aimed to determine and compare pathogen spectrum evaluated by culture PCR in bronchial secretion samples with regard underlying lung pathology. Methods: In this retrospective analysis, results from washes February 2022 September were collected 245 patients (48.2% male,...
Sarcoidosis is a systemic granulomatous disease that may differ in clinical presentation, organ involvement and severity among different populations. The primary objective was to evaluate demographic characteristics, stage, diagnostic work-up treatment of patients with sarcoidosis. sarcoidosis registry founded 2022 at the Medical University Vienna intended record from all over Austria who were diagnosed All relevant information collected time initial presentation then on an ongoing basis...
Many patients with severe coronavirus disease 2019 pneumonia exhibit signs of microthrombosis. Previous studies discussed intravenous fibrinolytic agents as potential add-on therapy in these patients. Therefore, we propose the inhalative administration fibrinolytics a possible safer alternative. This case series describes five white male patients, aged 51–78 years, treated off-label inhalation alteplase between November and December 2020. All suffered from acute respiratory syndrome 2...
Background: Elimination of a drug during renal replacement therapy is not only dependent on flow rates, molecular size and protein binding, but often influenced by difficult to predict membrane interactions. In vitro models allow for extensive profiling clearance using wide array hemofilters rates. We present bovine blood based in pharmacokinetic model intermittent therapy. Methods: Four different drugs were analyzed: gentamicin, doripenem, vancomicin teicoplanin. The investigated was added...
Personal protective equipment and adherence to disinfection protocols are essential prevent nosocomial severe acute respiratory syndrome coronavirus (SARS-CoV-2) transmission. Here, we evaluated infection control measures in a prospective longitudinal single-center study at the Vienna General Hospital, biggest tertiary care center Austria, with structurally planned low SARS-CoV-2 exposure. SARS-CoV-2-specific antibodies were assessed by Abbott ARCHITECT chemiluminescent assay (CLIA) 599...
Background and Objectives Several studies have shown that SARS-CoV-2 can induce a cytokine release storm which is major cause of disease severity death. Therefore, levels in the serum may predict survival patients with COVID-19.
<b>Background:</b> Sarcoidosis is a rare condition with clinical manifestations of the lung, liver, eyes, kidney, skin, heart, brain, muscles and bone. The incidence cardiac neurological manifestation often underestimated. <b>Methods:</b> Data from 129 individuals Austrian registry was analyzed by descriptive statistics. All patients underwent MRI brain for evaluation and/or sarcoidosis. <b>Results:</b> From (mean age 46.9 years, 39.5% male) histologically confirmed sarcoidosis, 54 (41.9%)...
<b>Aims and objectives:</b> The aim of bronchoscopic secretion sampling is to identify pathogenic organisms thus cause pulmonary infections. However, often performed during each diagnostic or therapeutic bronchoscopy in patients without a clinical suspicion for an acute respiratory infection. Nine twelve institutions from Austria Germany reported perform bronchial routinely bronchoscopy. the utility routine unknown. <b>Methods:</b> In this retrospective analysis, all results that were 257...
Several studies have shown that SARS-CoV-2 can induce a massive release of cytokines which contributes to disease severity and mortality. Therefore, cytokine levels in the serum may help predict survival COVID-19 patients.In this prospective trial, 88 patients who were hospitalised for enrolled. Blood samples peptide measurements taken at time closest hospitalisation, day 5, 9 13 (±1). The concentrations (IL-1α, IL-1β, IL-1RA, IL-6, L-7, L-10, IFN-γ TNF-α), chemokines (CCL-3, CCL-4 CCL-7)...
<b>Objective:</b> Hyponatremia may be due to tuberculosis (TB) by locally invading the hypothalamus, adrenal, or pituitary glands, through meningitis ectopic ADH production. This study assessed prevalence of TB in patients with hyponatremia and vice versa, its association mortality patients. <b>Methods:</b> The retrospective evaluated a cohort 107.532 (mean 58±18yrs, 52% female) 272.556 episodes (sodium<136mmol/L) 186 (positive M. culture, PCR result and/or Ziehl-Neelsen stain)....