A5076853312- Shape Memory Alloy Transformations
- Nanotechnology research and applications
- 3D Printing in Biomedical Research
- Pluripotent Stem Cells Research
- Tissue Engineering and Regenerative Medicine
- Cellular Mechanics and Interactions
- Electrospun Nanofibers in Biomedical Applications
- Microfluidic and Capillary Electrophoresis Applications
- Hydrogels: synthesis, properties, applications
- Engineering Education and Pedagogy
- Biomedical and Engineering Education
- Titanium Alloys Microstructure and Properties
- Experimental Learning in Engineering
- Metal and Thin Film Mechanics
- High Temperature Alloys and Creep
- Polymer composites and self-healing
- Advanced Sensor and Energy Harvesting Materials
- biodegradable polymer synthesis and properties
- Microfluidic and Bio-sensing Technologies
- Collagen: Extraction and Characterization
- Nuclear Materials and Properties
- Polymer Surface Interaction Studies
- Microstructure and mechanical properties
- Ferroelectric and Piezoelectric Materials
- Engineering Education and Curriculum Development
University of Wisconsin–Madison
2015-2024
Wisconsin Institutes for Discovery
2014-2024
Cornell University
2020
Beloit College
2020
Christian Brothers University
2020
U.S. National Science Foundation
2020
University of Minnesota
1998
University of Illinois Urbana-Champaign
1989
NCR (United States)
1977
One Cell Systems (United States)
1977
The widespread application of ionic hydrogels in a number applications like control microfluidic flow, development muscle-like actuators, filtration/separation and drug delivery makes it important to properly understand these materials. Understanding hydrogel properties is also from the standpoint their similarity many biological tissues. Typically, gel size sensitive outer solution pH salt concentration. In this paper, we develop models predict swelling/deswelling buffered solutions. An...
Summary Although bacterial cells are known to experience large forces from osmotic pressure differences and their local microenvironment, quantitative measurements of the mechanical properties growing have been limited. We provide an experimental approach theoretical framework for measuring live bacteria. encapsulated bacteria in agarose with a user‐defined stiffness, measured growth rate individual fit data thin‐shell model extract effective longitudinal Young's modulus cell envelope...
Human pluripotent stem cell (hPSC-) derived cardiomyocytes have potential applications in drug discovery, toxicity testing, developmental studies, and regenerative medicine. Before these cells can be reliably utilized, characterization of their functionality is required to establish similarity native cardiomyocytes. We tracked fluorescent beads embedded 4.4–99.7 kPa polyacrylamide hydrogels beneath contracting neonatal rat generated from hPSCs via growth-factor-induced directed...
Abstract Background: Products containing alcohol are commonly used with intravascular devices at insertion, to remove lipids from occluded during parenteral nutrition, and increasingly for the prevention treatment of device-related bloodstream infection. The effects on integrity remain unknown. Methods: Two types widely commercial peripherally inserted central catheters, one made polyether-urethane silicone, were exposed a 70% etha-nol lock solution up 10 weeks. Mechanical testing was...
Unidirectionally and orthogonally aligned thermoplastic polyurethane (TPU) nanofibers were electrospun using a custom-built electrospinning device. The unidirectionally fibers collected two parallel copper plates, the orthogonal sets of plates with alternate negative connections. Carbon nanotubes (CNT) polyacrylic acid (PAA) added to modify polymer solution. It was found that both CNT PAA capable increasing solution conductivity. TPU/PAA fiber showed highest degree orientation more than 90%...
In this study, a series of nanoindentations was made on NiTi shape memory alloy thin films at millinewton loads with Berkovich indenter. Mapping the indentation topography using atomic force microscopy reveals direct evidence that thermally induced martensitic transformation these allows for partial indent recovery nanoscale. Indeed, is nearly complete depths less than 100 nm. A hemispherical cavity model presented to predict an upper limit sharp indentations.
CuSn alloy nanowires capped with Ni were prepared using sequential electrodeposition of nickel and a copper/tin bronze into nanoporous alumina templates. The liberated suspended in solvents their behavior monitored optical microscopy. oriented spun circles as "nano stirbars" applied magnetic fields. These segmented also trapped between magnetized stripes, demonstrating that nonmagnetic metallic can be manipulated positioned by capping them ends.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTemplate Synthesis and Magnetic Manipulation of Nickel NanowiresAnne K. Bentley , Mohammed Farhoud Arthur B. Ellis Anne-Marie L. George C. Lisensky Wendy Crone View Author Information Department Chemistry, University Wisconsin–Madison, Madison, WI 53706 Physics Milwaukee School Engineering, Milwaukee, 53202 Beloit College, Beloit, 53511 Engineering Physics, 53706Cite this: J. Chem. Educ. 2005, 82, 5, 765Publication Date (Web):May 1, 2005Publication...
Novel blended scaffolds combining biobased polylactic acid (PLA) and thermoplastic polyurethane (TPU) were fabricated by thermally induced phase separation (TIPS) using two different solvents. Pure PLA TPU polymer 1,4-dioxane as the sole solvent exhibited typical ladder-like structures, while PLA/TPU same showed a more uniform microstructure. When de-ionized water was added to solution non-solvent, with mixed open cells greater interconnectivity. In compression tests, it found that...
Abstract Recent advances in bioengineering have enabled cell culture systems that more closely mimic the native cellular environment. Here, we demonstrated human induced pluripotent stem (iPSC)‐derived myogenic progenitors formed highly‐aligned myotubes and contracted when seeded on two‐dimensional micropatterned platforms. The differentiated cells showed clear nuclear alignment elongated dependent width of lanes. Topographical cues from micropatterning physiological substrate stiffness...
Truncation mutations in cardiac myosin binding protein C (cMyBP-C) are common causes of hypertrophic cardiomyopathy (HCM). Heterozygous carriers present with classical HCM, while homozygous early onset HCM that rapidly progress to heart failure. We used CRISPR-Cas9 introduce heterozygous (cMyBP-C+/−) and (cMyBP-C−/−) frame-shift into MYBPC3 human iPSCs. Cardiomyocytes derived from these isogenic lines were generate micropatterns engineered tissue constructs (ECTs) characterized for...
Abstract Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) exhibit a fetal phenotype that limits in vitro and therapeutic applications. Strategies to promote cardiomyocyte maturation have focused interventions on differentiated hPSC-CMs, but this study tests priming of early cardiac progenitor cells (CPCs) with polyinosinic-polycytidylic acid (pIC) accelerate maturation. CPCs were from hPSCs using monolayer differentiation protocol defined small molecule Wnt temporal modulation,...
The mental health crisis in graduate education combined with low treatment rates among engineering students underscores the need for programs to provide effective methods promote well-being. There is an extensive body of neuroscience research showing that contemplative practices, such as mindfulness, produce measurable effects on brain function and overall We hypothesized a mindfulness-based training program designed would improve emotional well-being and, secondarily, enhance capacity. An...
Nanoscale science and engineering (NSE) nanotechnology are emerging fields that have captured the attention of scientists engineers, as well mainstream media. However, general public is relatively unaware NSE, schools (both K−12 undergraduate institutions) rarely include part their curriculum. To help fill this gap in student understanding to engage a broad base learners, suite interdisciplinary activities connecting stained glass artistry was created. The has been successfully adapted for...