A5050068835- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Cytomegalovirus and herpesvirus research
- Immunotherapy and Immune Responses
- Vaccine Coverage and Hesitancy
- Influenza Virus Research Studies
- Bacterial Infections and Vaccines
- Immune Response and Inflammation
- Diphtheria, Corynebacterium, and Tetanus
- Hematopoietic Stem Cell Transplantation
- Diabetes and associated disorders
- Neonatal Respiratory Health Research
- SARS-CoV-2 and COVID-19 Research
- Adipokines, Inflammation, and Metabolic Diseases
- vaccines and immunoinformatics approaches
- Viral Infections and Immunology Research
- Autism Spectrum Disorder Research
- Metabolism and Genetic Disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Infant Nutrition and Health
- Genetics and Neurodevelopmental Disorders
- Viral-associated cancers and disorders
- Neonatal Health and Biochemistry
- Animal Virus Infections Studies
- Effects and risks of endocrine disrupting chemicals
Universität Innsbruck
2016-2025
Cohen Children's Medical Center
2017-2025
Northwell Health
2017-2025
Hofstra University
2018-2024
Donald & Barbara Zucker School of Medicine at Hofstra/Northwell
2018-2022
Ärztliche Gesellschaft zur Gesundheitsförderung e.V
2021
RELX Group (Netherlands)
2017
Johnson University
1996-2015
Rutgers, The State University of New Jersey
1996-2015
Austrian Academy of Sciences
2006-2012
Previous studies have reported decreased birth weight associated with increased air pollutant concentrations during pregnancy. However, it is not clear when pregnancy increases in pollution are the largest differences weight.Using natural experiment of declines 2008 Beijing Olympics, we evaluated whether having specific months (i.e., 1st…8th) Olympics period was larger weights, compared pregnancies same dates 2007 or 2009.Using n = 83,672 term births to mothers residing four urban districts...
Phthalate exposure is widespread among pregnant women and may be a risk factor for preterm birth. To investigate the prospective association between urinary biomarkers of phthalates in pregnancy birth individuals living US. Individual-level data were pooled from 16 preconception studies conducted Pregnant who delivered 1983 2018 provided 1 or more urine samples during included. Urinary phthalate metabolites quantified as exposure. Concentrations 11 standardized dilution mean repeated...
The BM is well understood to play a key role in plasma cell homing and survival mice. In humans, cells their functions are less characterized. this study, we used paired bone biopsies from the femur shaft blood samples persons of different ages analyze age‐related changes memory B cells. Our results demonstrated that were mainly located BM, while higher percentage was peripheral than BM. frequency both sources decreased with age, immature naïve unaffected. An decline tetanus‐...
Phthalates and bisphenol A (BPA) are ubiquitous environmental toxicants, present in high concentrations numerous consumer products. We hypothesized that maternal exposure to phthalates BPA pregnancy is associated with shortened gestation.Urinary phthalate metabolites from 72 pregnant women were measured at the last obstetric clinic visit prior delivery. Using linear regression models, we estimated change gestational age each interquartile range (IQR) increase metabolite concentration.IQR...
Problem Interleukin‐10 (IL‐10) is thought to be a key cytokine for the maintenance of pregnancy. Here we examined expression profiles IL‐10 and cyclo‐oxygenase‐2 (COX‐2), effect on COX‐2 prostaglandin release in human placenta from preterm labor deliveries associated with chorioamnionitis. Method study Placental tissues term were processed ex vivo placental explant culture system. was assessed by enzyme‐linked immunosorbent assay (ELISA) immunohistochemical (IHC) analysis. evaluated IHC,...
The immune system undergoes profound age-related changes, including a gradual increase in the production and circulation of proinflammatory cytokines. Despite known capacity fibroblasts to produce cytokines, little is so far about inflammatory response cellular stress such as viral and/or bacterial infection context aging. Therefore aim this study was analyze levels IL6 IL8 secretion supernatants human skin from young elderly persons. Cytokine chemokine analyzed before after vitro cells with...
Demographic changes and a more active life-style in older age have contributed to an increasing public awareness of the need for lifelong vaccination. Currently many persons been vaccinated against selected pathogens during childhood but lack regular booster immunizations. The impact vaccinations when started late life was analyzed open, explorative trial by evaluating immune response tetanus diphtheria healthy individuals. 252 aged above 60 years received vaccination tetanus, diphtheria,...
Abstract After repeated antigen exposure, both memory and terminally differentiated cells can be generated within CD8 + T cells. Although, during their differentiation, activated may first lose CD28, CD28 − eventually express CD57 as a subsequent step, population of (DP) identified in the peripheral blood. How this is distinct from (DN) cells, better characterized non‐activated/early‐activated senescent‐like cell subsets currently unknown. Here, RNA expression four isolated human PBMCs was...