A5101759340- Medical Research and Treatments
- Traditional Chinese Medicine Studies
- Traditional Chinese Medicine Analysis
- Neurological Disease Mechanisms and Treatments
- Peroxisome Proliferator-Activated Receptors
- Viral Infectious Diseases and Gene Expression in Insects
- Mesenchymal stem cell research
- Liver Disease Diagnosis and Treatment
- Acute Kidney Injury Research
- Reproductive Biology and Fertility
- Healthcare and Venom Research
- Cancer, Hypoxia, and Metabolism
- Biochemical and Molecular Research
- Pediatric health and respiratory diseases
- Cervical Cancer and HPV Research
- Animal Virus Infections Studies
- Flavonoids in Medical Research
- Respiratory Support and Mechanisms
- Radiomics and Machine Learning in Medical Imaging
- Gut microbiota and health
- Phytochemical compounds biological activities
- Cancer-related Molecular Pathways
- Cell Adhesion Molecules Research
- Respiratory viral infections research
- Atherosclerosis and Cardiovascular Diseases
Chengde Medical University
2020-2024
Hebei Medical University
2020-2023
Kunming Medical University
2023
Ningxia Medical University
2016-2023
He University
2023
He Eye Hospital
2023
Shanghai Institute of Technology
2023
Qinghai Provincial Peoples Hospital
2022
Sun Yat-sen University
2011-2022
The Seventh Affiliated Hospital of Sun Yat-sen University
2020-2022
T cells are required for normal host defense against fungal infection, and individuals with cell.deficiency syndromes highly susceptible to pathogens. Interleukin (IL)-17A is a proinflammatory cytokine that interconnects myeloid lymphoid defense. The role of murine (m) IL-17A/mIL-17A receptor (R) interactions was evaluated in model systemic candidiasis. In response challenge Candida albicans, expression mIL-17A induced, IL-17AR knockout (IL-17AR−/−) mice had dosedependent, substantially...
The aim of the present study was to investigate effects prebiotics (containing fructooligosaccharides, xylooligosaccharides, polydextrose, and resistant dextrin) intake on immune function intestinal microbiota structure in perioperative patients with colorectal cancer (CRC).A randomized, double-blind, no-treatment parallel control clinical trial involving 140 (90 men 50 women, aged 40-75 y) CRC performed. Patients were randomly divided into two groups: an intervention group (prebiotic group,...
Malnutrition is a common complication in the dialysis population, both hemodialysis and peritoneal (PD). We report our exploratory study on characteristics of intestinal microbiota nutritional status PD patients. The patients were evaluated, their feces collected for 16S rRNA gene V3-V4 regions amplification high-throughput sequencing. differences between well-nourished (W) malnourished (M) groups compared. studied genera operational taxonomic units (OTUs) within genus patients, initially...
To investigate the curative effects of HUC-MSCs combined with USW on spinal cord injury (SCI) and inflammatory microenvironment to explore regulatory mechanisms MK2/TTP signalling pathway NLRP3 inflammasome.The SCI rat model was established using modified Allen method; rats were administered USW, HUC-MSCs, combination therapy HUC-MSCs; therapeutic efficacies in each group monitored represented BBB score. levels observed HE staining IF. The microglia polarisation state released contents...
Abstract Our previous research has shown that melatonin (MLT) can reduce cryopreserved ovarian damage in mice. Yet, the molecular mechanism of MLT protection is still unclear. Some studies have receptor 1 (MT1) very important for animal reproductive system. To evaluate whether exerts its protective effect on mice tissue via MT1, we added antagonist MT1/MT2 (Luzindor) or MT2 (4P‐PDOT) to freezing solution, followed by cryopreservation and thawing tissue. The levels total superoxide dismutase...
To evaluate the utility of Golgi protein 73 (GP73) in diagnosis non-alcoholic steatohepatitis (NASH) and hepatic fibrosis (HF) staging.
To analyze the clinical manifestations of primary adrenal insufficiency in Chinese boys, to investigate prevalence DAX1 and SF1 gene mutations, explore association between mutations manifestations.A total 25 boys with were enrolled. Mutational analysis genes was done by direct sequencing.DAX1 found 40% (10 25) 46,XY phenotypic referred insufficiency, six these novel. One mutation identified. These patients demonstrated diverse presentations. There no definite genetic mutations.DAX1 are a...
To study the association between expression of H3K27me3 and ACat2 (a folate metabolic protein), in order to elucidate protective mechanism folic acid (FA) neural tube defects (NTDs).Eighteen female SD rats were randomly divided into normal, NTD FA group. group was induced by all-trans retinoic (ATRA) at E10d. fed with supplementation since 2 weeks before pregnancy, followed ATRA induction. At E15d, level embryonic determined ELISA. Neural stem cells (NSCs) isolated. Cell proliferation...
In this paper, we study hospital bed planning problem for a gynecological ward in China. We first proposed mixed integer programming (MIP) model considering deterministic length of stay (LOS) to assign patients available beds. Since statistical analysis empirical hospitalization data reveals that variance inpatient's LOS is significant. Therefore, based on the further MIP taking stochastic into consideration. Both models could be solved by standard linear solver CPLEX. Numerical experiments...
The search data of E-commerce site reflects millions online consumers' concerns and interests, as well trends their behavior, so it can also provide essential basis for the study daily number orders. This paper firstly establishes a conceptual framework, revealing that there is certain correlation lead-lag relationship between Ecommerce Then, by empirical analysis orders an site, processes index builds prediction model based on it, which confirming this statistically significant. Prediction...
Human epidermal cell sheet (human-ECS) is a feasible treatment option for wound injury. Traditionally, researchers often use murine 3T3 fibroblast cells as feeder layer to support human grafts, thus increase risk deliver animal-borne infection. To overcome the potential risks involved with xenotransplantation, we develop foreskin culture system and investigate effects of human-ECS on second-degree burn healing in mini-pig order more effective safer therapies enhance human.Human keratinocytes...
Tanshinone IIA (TanIIA) has multiple biological functions and already been clinically used to treat many cardiovascular diseases. TanIIA is a photoactive molecule can be excited by light generate 3 TanIIA*. Generation of TanIIA* photosensitization indicates that may serve as photosensitizer bring photodynamic damage organisms. Therefore, human choroidal melanoma MUM-2B cell was chosen superficial tumor model the effect on cells evaluated in this study. The results showed could singlet oxygen...
Pollen-mediated gene transformation does not require tissue culture and is easy to apply.In the present study, we investigate cytological basis for approach.Fresh pollen was taken from maize plants (Zea mays cv 'Zhengdan 958') treated under ultrasonication mixed with plasmid DNA harboring green fluorescence protein (GFP) gene.Treated artificially pollinated onto silks of ears.The expression GFP in grains, tubes embryo were observed a microscope.Pollen grains had strong autoflorescent...