A5038742241- Cervical Cancer and HPV Research
- Epigenetics and DNA Methylation
- Endometrial and Cervical Cancer Treatments
- Advanced Radiotherapy Techniques
- Global Cancer Incidence and Screening
- Acute Myeloid Leukemia Research
- Histone Deacetylase Inhibitors Research
- Lung Cancer Diagnosis and Treatment
- Platelet Disorders and Treatments
- Colorectal and Anal Carcinomas
- Cancer-related molecular mechanisms research
- Advances in Oncology and Radiotherapy
- Hepatitis B Virus Studies
- Radiomics and Machine Learning in Medical Imaging
- Advanced biosensing and bioanalysis techniques
- Artificial Intelligence in Healthcare
- Vaccine Coverage and Hesitancy
- Acute Lymphoblastic Leukemia research
- Extracellular vesicles in disease
- Prostate Cancer Treatment and Research
- Inflammasome and immune disorders
- Infective Endocarditis Diagnosis and Management
- Cell death mechanisms and regulation
- COVID-19 epidemiological studies
- Childhood Cancer Survivors' Quality of Life
Teesside University
2025
Henan Provincial People's Hospital
2019-2024
Zhengzhou University
2019-2024
Central South University
2023-2024
First Affiliated Hospital of Xi'an Jiaotong University
2018-2020
Xi'an Jiaotong University
2016-2019
Zhengzhou People's Hospital
2019
Sepsis is one of the medical conditions with a high mortality rate and lacks specific treatment despite several years extensive research. Bacterial extracellular vesicles (bEVs) are emerging as focal target in pathophysiology sepsis. Extracellular (EVs) derived from pathogenic microorganisms carry factors such carbohydrates, proteins, lipids, nucleic acids, virulence regarded “long-range weapons” to trigger an inflammatory response. In particular, small size bEVs can cross blood-brain...
In addition to their established action of synthetic lethality in tumor cells, poly(ADP-ribose) polymerase inhibitors (PARPis) also orchestrate immune microenvironment (TIME) that contributes suppressing growth. However, it remains not fully understood whether and how PARPis trigger tumor-targeting responses.
Abstract Tumor‐associated macrophages (TAMs) play critical roles in reprogramming other immune cells and orchestrating antitumor immunity. However, the interplay between TAMs tumor responsible for enhancing evasion remains insufficiently understood. Here, we revealed that interleukin (IL)‐1β was among most abundant cytokines within vitro tumor‐macrophage coculture system, enhanced IL‐1β expression associated with impaired cytotoxicity of CD8 + T human ovarian cancer, indicating possibility...
Purpose The primary purpose of the study was to explore impact health workers’ awareness artificial intelligence (AI) on their workplace well-being, addressing a critical gap in literature. By examining this relationship through lens Job demands-resources (JD–R) model, aimed provide insights into how perceptions AI integration jobs and careers could influence informal learning behaviour and, consequently, overall well-being workplace. study’s findings inform strategies for supporting...
Background: Video-based interventions have the potential to contribute long-lasting improvements in health-seeking behaviours. Ghana's upsurge rate of information and communication technology usage presents an opportunity improve awareness HPV vaccination screening rates cervical cancer among women Ghana. This research aimed assess impact video-based educational intervention centred on Health Belief Transtheoretical Models behavioural changes promoting vaccination, carcinoma willingness Pap...
The aim of the present study was to compare intensity‑modulated radiation therapy (IMRT) and volumetric modulated arc (VMAT) in irradiation lung cancer. Plans 14 patients were compared. results demonstrated that peripheral cancer, V5 (%) partial‑arc (PA)‑VMAT decreased compared with IMRT, single‑arc (SA)‑, double (2PA)‑VMAT. V30 IMRT SA‑, PA‑ 2PA‑VMAT. In case planning target volume (PTV) not encompassing mediastinum central conformality index (CI) heterogeneity (HI) SA‑VMAT improved PA‑,...
Background: Cervical cancer (CC) is the fourth most commonly diagnosed among women. Ghana a low-middle- income country with annual cases of 3151 and 2119 deaths. The high prevalence rate cervical in mainly due to ineffective preventive measures insufficient knowledge about disease. Therefore, our objective was evaluate level awareness attitude towards human papillomavirus its vaccine Ghanaians. Methods: This descriptive cross-sectional survey on carried out from March 2019 February 2020....
Lung cancer is the leading cause of morbidity and mortality worldwide. Apart from tobacco smoke dietary factors, microbial infections have been reported as third cancers globally. Deciphering association between microbiome lung will provide potential biomarkers novel insight in progression. In this current study, we performed a meta-analysis to decipher possible C. pneumoniae human papillomavirus (HPV) risk cancer.Literature search was conducted most English Chinese databases. Data were...
Pneumonia is an infection of the lungs that characterized by high morbidity and mortality. The use machine learning systems to detect respiratory diseases via non-invasive measures such as physical laboratory parameters gaining momentum has been proposed decrease diagnostic uncertainty associated with bacterial pneumonia. Herein, this study conducted several experiments using eight models predict pneumonia based on biomarkers, parameters, features. We perform machine-learning analysis 535...
Background: Gemcitabine and cisplatin combined with conventional radiotherapy in treating patients cervical cancer, resulted a favourable conclusion but accompanied high toxicity. The objective of our research was to assess the tolerability, efficacy feasibility dual chemotherapy addition image-guided adaptive brachytherapy highly conformal external beam radiation therapy. Methods & Materials: From June 2011 November 2013, 81 cancer FIGO stage IB2-IIIB medical records were retrospectively...
Hypomethylating agents (HMAs), such as decitabine (DAC), are currently used first-line therapy for patients with high-risk myelodysplastic syndromes (MDS) and acute myelogenous leukemia (AML) not eligible standard chemotherapies. Exacerbation of thrombocytopenia is one the prevalent complications after HMA treatment. Eltrombopag (EP), an oral thrombopoietin receptor agonist, can efficiently stimulate megakaryopoiesis elevate platelet counts in MDS/AML patients. However, significance...
Introduction Immune checkpoint inhibitor (ICI) therapy has been proven to be a highly efficacious treatment for colorectal adenocarcinoma (COAD). However, it is still unclear how identify those who might benefit the most from ICI therapy. Hypoxia facilitates progression of tumor different aspects, including proliferation, metabolism, angiogenesis, and migration, improves resistance ICI. Therefore, essential conduct comprehensive understanding influences hypoxia in COAD biomarker predicting...
In many developing countries, most children cannot meet minimum dietary diversity (MDD), defined as the consumption of four or more seven food groups. Ghana, only 35% met MDD nationwide in 2017, but rates are worse among rural poor and resource-constrained individuals like Head Porters (HPs). The current study investigated correlates HPs aged 6-23 months old Ghana.A cross-sectional survey was carried out 2021 423 selected purposively from eight market centers two commercial cities. A...
Abstract Background The posterior-inferior border of symphysis (PIBS) point system is a novel vaginal dose-reporting method and simple reliable proposed by the Medical University Vienna for both external-beam radiotherapy (EBRT) brachytherapy (BT). In this multicenter study, we sought to first evaluate radiation dose in Chinese cervical cancer patients according PIBS then analyze factors influencing distribution. Methods We collected data from medical records 936 who underwent concurrent...
Aim: Cervical cancer is still one of the most common gynecologic cancers in world. Since cervical a potentially preventive cancer, earlier detection effective technique for decreasing worldwide incidence illness. Materials and methods: This research presents novel ensemble predicting risk. Specifically, authors introduce voting classifier that aggregates prediction probabilities from multiple machine-learning models: logistic regression, K-nearest neighbor, decision tree, XGBoost multilayer...
At present, methods of radiotherapy simulation for breast cancer based on four‑dimensional computerised tomography (4D‑CT) or three‑dimensional CT (3D‑CT) remain controversial. In the present study, 7 patients with residual tissue received whole 3D‑CT and 4D‑CT simulation. For plan, four types images were produced, including end inspiration expiration, acquired by maximal intensity projection (MIP) average (AIP). clinical target volume (CTV) plan (PTV) marginally higher compared plan....