A5075954289- Venous Thromboembolism Diagnosis and Management
- Aortic aneurysm repair treatments
- Peripheral Artery Disease Management
- Diagnosis and Treatment of Venous Diseases
- Aortic Disease and Treatment Approaches
- Vascular Procedures and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Asphalt Pavement Performance Evaluation
- Cancer, Hypoxia, and Metabolism
- Bone health and osteoporosis research
- Cerebrovascular and Carotid Artery Diseases
- Atherosclerosis and Cardiovascular Diseases
- Dermatologic Treatments and Research
- Case Reports on Hematomas
- Osteoarthritis Treatment and Mechanisms
- Vascular anomalies and interventions
- Atrial Fibrillation Management and Outcomes
- Concrete and Cement Materials Research
- Infrastructure Maintenance and Monitoring
- Pressure Ulcer Prevention and Management
- Dendrimers and Hyperbranched Polymers
- MicroRNA in disease regulation
- Abdominal vascular conditions and treatments
- COVID-19 and healthcare impacts
- Infectious Aortic and Vascular Conditions
Sir Run Run Shaw Hospital
2015-2025
Zhejiang University
2015-2025
California State University, Chico
2024
State Key Laboratory of Natural and Biomimetic Drugs
2023-2024
Peking University
2023-2024
Fourth Affiliated Hospital of Anhui Medical University
2023
Anhui Medical University
2023
Shaoxing University
2008-2020
University of Calgary
2018
Therapeutics Clinical Research
2013
Osteoarthritis (OA) is a degenerative joint disease characterized by progressive erosion of the articular cartilage and inflammation. Mesenchymal stem cells' (MSCs) transplantation in OA treatment emerging, but its clinical application still limited low efficiency oriented differentiation. In our study, to improve therapeutic efficiencies MSCs carbonic anhydrase IX (CA9) siRNA (siCA9)-based inflammation regulation Kartogenin (KGN)-based chondrogenic differentiation, combination strategy...
Abstract Atherosclerosis (AS), a leading cause of cardio-cerebrovascular disease worldwide, is driven by the accumulation lipid contents and chronic inflammation. Traditional strategies primarily focus on reduction to control AS progression, leaving residual inflammatory risks for major adverse cardiovascular events (MACEs). While anti-inflammatory therapies targeting innate immunity have reduced MACEs, many patients continue face significant risks. Another key component in progression...
Diabetic foot ulcers (DFUs) represent the most frequent diabetes-related cause for hospitalization (1). Currently, coronavirus disease 2019 (COVID-19) pandemic is likely to pose a threat delivery of care, leading some unintended consequences. We aimed determine impact COVID-19 outbreak on patients with DFUs at multidisciplinary center in China. In first part this study, an interrupted time-series design was applied estimate trends before generate predicted value 2020. Monthly records from...
To analyze the disease burden and inequalities of lower extremity peripheral artery disorders (LEPAD) among people aged 40 above in Belt Road partner countries from 1990 to 2021. Data were retrieved Global Burden Disease 2021 database. The age-standardized prevalence rates, mortality annual rate years lived with disability (YLDs) LEPAD analyzed. Trends measured using estimated percentage change (EAPC), slope index inequality (SII) concentration used quantify absolute relative inequalities....
To study the relationship of plasma homocysteine (Hcy), bone turnover biomarkers (BTB), and mineral density (BMD) with osteoporotic fracture (OPF) in elderly people.Eighty-two patients (aged 65 years or older) admitted to our orthopedics department between October 2014 May 2015 were randomly divided into three groups: 1) OPF group: 39 cases mean age 81.82±5.49 years, which included 24 females 15 males; 2) high-energy (HEF) 22 78.88±5.75 16 six 3) non-bone-fracture 21 79.75±5.47 without...
Aggregate segregation compromises the homogeneity of asphalt pavement, which diminishes road performance mixture. The behavior and damage mechanism mixture are complex. To investigate mechanical properties cracking mixtures with varying degrees aggregate segregation, dense-graded nominal maximum size 13.2 mm (AC-13) Open Graded Friction Course 16.0 (OGFC-16) were designed. Indirect tensile test digital image correlation (DIC) technology was employed to analyze strain distribution evolution...
Vascular smooth muscle cells (VSMCs) in the normal arterial media continually express contractile phenotypic markers which are reduced dramatically response to injury. Tripartite motif-containing proteins a family of scaffold shown regulate gene silencing, cell growth, and differentiation. We here investigated biological role tripartite 28 (TRIM28) 27 (TRIM27) VSMCs. observed that siRNA-mediated knockdown TRIM28 TRIM27 inhibited platelet-derived growth factor (PDGF)-induced migration human...
Abstract Vulcanizing reagent (VR) suspensions with different sulfur additions were mixed CNTs and SBR latex, then powder CNTs/SBR (PSBR) composites prepared by spray‐drying process. Investigations showed that VR have significant influences on the properties of CNTs/PSBR composites. With increment additions, glass transition temperature ( T g ) increased gradually, reached maximum when addition was 4.0 phr, it would decrease if continued to rise. The elongation at break vulcanizates decreased...
Objective. Blood vessels of bone are thought to influence osteogenesis bone. No clinical studies have determined whether angiogenesis is related mass and gene expression growth factors. We compared marrow endothelial progenitor cells (EPC), which control in postmenopausal women incurring fragility fracture, with osteoporosis or traumatic fracture normal (COM). Methods. Bone specimens were obtained from age-matched COM. Mononuclear isolated EPC detected by flow cytometry. The levels specific...
BACKGROUND We aimed to investigate the role of PDCD4-mediated Akt signaling pathway in vascular endothelial cell injury caused by ischemia-reperfusion lower extremities. MATERIAL AND METHODS Ten rats were used as control, while 50 for creating disease models and assigned 5 groups: model group (no injection), NC (injected with vectors containing PDCD negative control sequence), sh-PDCD4 IGF-1 IGF-1), sh-PDCD4+IGF-1 sequence). RESULTS Compared group, expression levels PDCD4 mRNA protein, well...
Inflammatory myofibroblastic tumor (IMT) of the biliary tract is rare, and often difficult to diagnose or distinguish from other tumors due its atypical clinical presentation nonspecific radiological features. Histologically, IMTs are (myo)fibroblastic neoplasms with a prominent inflammatory infiltrate. They characterized by receptor tyrosine kinase gene rearrangements, most involving an anaplastic lymphoma (ALK ) translocation. The final diagnosis IMT depends on histopathology...