A5088423070- Cerebrovascular and genetic disorders
- Multiple Sclerosis Research Studies
- Acute Ischemic Stroke Management
- Neurological Disease Mechanisms and Treatments
- Stroke Rehabilitation and Recovery
- Gut microbiota and health
- Medical Research and Treatments
- Sepsis Diagnosis and Treatment
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Health and Wellbeing Research
- Diet and metabolism studies
- Long-Term Effects of COVID-19
- Peripheral Neuropathies and Disorders
- Dementia and Cognitive Impairment Research
- Autoimmune Neurological Disorders and Treatments
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Antifungal resistance and susceptibility
- Health Promotion and Cardiovascular Prevention
- Infectious Encephalopathies and Encephalitis
- Heme Oxygenase-1 and Carbon Monoxide
- Cardiovascular Health and Risk Factors
- Nutrition, Genetics, and Disease
- Phagocytosis and Immune Regulation
- Metabolomics and Mass Spectrometry Studies
Yangzhou University
2025
Sun Yat-sen University
2013-2024
Third Affiliated Hospital of Sun Yat-sen University
2013-2024
Guangdong Provincial Hospital of Traditional Chinese Medicine
2021
E Ink (South Korea)
2021
National Natural Science Foundation of China
2013-2021
Army Medical University
2014
The health behaviors of hypertensive stroke patients in China are not satisfactory. In this study, we tested the effect a Health Belief Model Comprehensive Reminder System on and blood pressure control ischemic after occurrence hospital discharge.A randomized, parallel-group, assessor-blinded experimental design yielded participation 174 hospitalized patients. intervention consisted face-to-face telephone belief education, patient calendar handbook, weekly automated short-message services....
Abstract Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a cerebral small vessel disease that carries mutations in NOTCH3 . The clinical manifestations are influenced by genetic environmental factors may include gut microbiome. Results We investigated the fecal metagenome, metabolome, serum neurotransmitters, cytokines cohort of 24 CADASIL patients 28 healthy household controls. integrated-omics study showed harbored an...
ABSTRACT In this paper, we consider the following a fractional chemotaxis–fluid system modeling coral fertilization with tensor‐valued sensitivity in . Here function satisfies We show that if and initial data satisfy or then admits unique global mild solution, also determine asymptotic behavior optimal convergence rates of solution.
Individuals with hypertension are at risk of stroke, and patients stroke histories experiencing another stroke. At this time, however, only a few studies have reported on prevention knowledge health behaviors among hypertensive who had an initial The purpose study was to determine analyze the association between these 2 variables stroke.With use descriptive correlational design, sample 112 recruited from departments neurology 3 hospitals in Guangzhou, China. Each patient completed reliable,...
Background and purpose The present study aimed to examine how long‐term migration high‐altitude regions affects mentality cognition, the correlation with various physiological biochemical changes. Methods WHO N eurobehavioral C ore T est B attery, R aven's S tandard P rogressive M atrices ( RSPM ) ittsburgh leep Q uality I ndex questionnaire were used assess 141 young male subjects who lived in plain 217 had migrated a 4500 m region there for 1–5 years. Arterial oxyhemoglobin saturation,...
Objective: The triglyceride‑glucose (TyG) index is a reliable surrogate of insulin resistance and marker for ischemic stroke (IS) incident. Whether the TyG predicts outcome remains uncertain. This study investigated prognostic value in critically ill patients. Methods: was retrospective observational that included patients, all data were extracted from eICU Collaborative Research Database. calculated as ln (fasting glucose level [mg/dL] × triglyceride [mg/dL]/2). outcomes hospital intensive...
Dysbiosis of gut microbiota might promote the pathophysiological process aCSVD.
Gut microbiota associated with longevity plays an important role in the adaptation to damaging stimuli accumulated during aging process. The mechanism by which longevity-associated protects senescent host remains unclear, while metabolites of gut bacteria are particular interest. Here, integrated analysis untargeted metabolomics and 16S rRNA gene sequencing was used characterize metabolite profiles long-lived individuals (aged ≥90 years) comparison old-elderly 75-89 years), young-elderly...
Background Risk factor management via behavioral change contributes substantially to secondary stroke prevention. The health belief model identified self-perceived risk as a significant in behavior change. In previous studies, people have tended incorrectly estimate their of stroke. Little is known about the differences knowledge and behaviors patients who had with different risks recurrence China. Objective aims this study were determine accuracy compare hypertensive at strata. Methods...
White matter hyperintensity (WMH) is a common neuroimaging marker of cerebral small vessel disease (SVD) and critical independent predictor motor dysfunction, which increases the risk disability, morbidity, mortality. However, mechanism underlying relationship between WMH function has not yet been fully clarified. It was hypothesized that cognitive impairment mediates dysfunction in patients with SVD, were considered outcome variables, respectively.
To investigate health behaviours and family function in stroke survivors, evaluate the relationships among them. Patients who were diagnosed with before went back to neurology clinic between August 2011 February 2012 a tertiary hospital Guangzhou, China recruited for this study. that discharged living at home least two months asked complete Family Assessment Device (FAD) Health Promoting Lifestyle Profile, version II (HPLP-II) questionnaires. Individual items scored 1 4 points, survey scores...
BACKGROUND: Previous research has shown that men and women have different levels of stroke knowledge differing health behaviors, which are important factors affecting blood pressure, as hypertension is a key risk factor for occurrence. There been little on the effects sex association between these 2 variables before onset among Chinese hypertensive patients. METHODS: A cross-sectional study convenience sampling method were used. 272 male 118 female patients recruited. Each patient completed...
Abstract Natural killer (NK) cells are enriched in the central nervous system aging-related atheriosclerotic cerebral small vessel disease (aCSVD), but their roles and underlying mechanism remain to be elucidated. To identify potential cytotoxic molecules released by NK aCSVD lesions, proteomic analysis of cerebrospinal fluid (CSF), plasma, peripheral from patients with were performed. We found that integrin β2 (ITGB2), cathepsin D (CTSD), granzyme H (GZMH) highly expressed cells. ITGB2...
Background Our previous study had demonstrated that ulinastatin (UTI) a neuroprotective effect in experimental autoimmune encephalomyelitis (EAE). Methylprednisolone has been recommended to be standard drug multiple sclerosis (MS) therapies. The present was investigate the protective effects of UTI combined methylprednisolone EAE. Methods Mice were divided into treatment group, group with and methylprednisolone, normal saline control group. EAE mice induced groups receiving different...
Neuromyelitis optica spectrum disorders seriously hinder social participation. Only clarifying the status of participation and factors most strongly influencing it can promote better-targeted support for those with neuromyelitis disorders.To explore among persons disorders.138 were recruited by convenience sampling. They completed Impact on Participation Autonomy Questionnaire, rated using Barthel index, Beck Anxiety Inventory Depression Inventory. The data used to evaluate a generalized...
This study aimed to establish a comprehensive set of nursing-sensitive quality indicators (NSQIs) for patients with dysphagia following tracheotomy due acquired brain injury (ABI), based on the 'structure-process-outcome' model. A Delphi survey. The research utilised mixed-methods approach, including systematic literature reviews, qualitative interviews and two rounds expert consultations. diverse team comprising specialists in rehabilitation nursing management conducted research, which...
Gut microbiome plays a pivotal role in combating diseases and facilitating healthy aging, natural products derived from biosynthetic gene clusters (BGCs) of the human exhibit significant biological activities. However, gut long-lived populations remain poorly understood. Here, we integrated six cohorts populations, encompassing total 1029 fecal metagenomic samples, employed single sample assembled BGCs (MSSA-BGCs) analysis pipeline to investigate their associated species. Our findings reveal...
Objective To explore the mediating effect of health belief on relationship between knowledge and behavior among hypertensive patients with stroke. Methods The questionnaire Stroke Knowledge Questionnaire (SKQ), Short Form Health Belief Model Scale(SF-HBMS)and scale for stroke patients(HBS-SP) were used to investigate knowledge, 151 patients. The structural equation model was established using SPSS 17.0 Mplus7.0 software. Results The total score SKQ, SF-HBMS HBS-SP...
Objective: To identify differences in health beliefs and behaviors among hypertensive patients with or without stroke, to investigate the relationship between 2 variables.Methods: With convenience sampling, 66 stroke patients, 77 105 normotensives from Guangzhou participated this study.The Champion belief model scale (CHBMS) health-promoting lifestyle profile II (HPLP II) were used measure patient's behaviors.Results: Normotensives had their lowest scores on perceptual disturbance (2.73 ±...