Zhanfei Li

ORCID: 0000-0002-7820-7162
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About
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Research Areas
  • Pelvic and Acetabular Injuries
  • Trauma Management and Diagnosis
  • Abdominal Trauma and Injuries
  • Acute Ischemic Stroke Management
  • Ferroptosis and cancer prognosis
  • S100 Proteins and Annexins
  • Spinal Fractures and Fixation Techniques
  • Cardiac Arrest and Resuscitation
  • Medical Research and Treatments
  • Blood transfusion and management
  • Trauma and Emergency Care Studies
  • Liver Disease and Transplantation
  • Mitochondrial Function and Pathology
  • Gynecological conditions and treatments
  • Aortic Disease and Treatment Approaches
  • Congenital Diaphragmatic Hernia Studies
  • Immune cells in cancer
  • Central Venous Catheters and Hemodialysis
  • Inflammatory Biomarkers in Disease Prognosis
  • Maternal and fetal healthcare
  • Autopsy Techniques and Outcomes
  • Barrier Structure and Function Studies
  • Child Therapy and Development
  • Pregnancy-related medical research
  • Airway Management and Intubation Techniques

Tongji Hospital
2008-2025

Huazhong University of Science and Technology
2008-2025

Lanzhou University
2023

First Hospital of Lanzhou University
2023

Peking Union Medical College Hospital
2019

Third Affiliated Hospital of Zhengzhou University
2013

Sepsis-associated encephalopathy (SAE) often manifests in severe diffuse cerebral dysfunction due to an aberrant systemic immune response infection. The underlying pathophysiology of SAE is not entirely understood but likely a multifactorial process that involves disruption cell death mechanism. Ferroptosis novel form programmed characterized by iron accumulation and lipid peroxidation, leading inflammatory cascade glutamate release. We hypothesized ferroptosis involved the...

10.1097/shk.0000000000001893 article EN Shock 2022-01-20

Tissue plasminogen activator (tPA) is recommended by the FDA to dissolve intravascular clots after acute ischemic stroke (AIS). However, it may contribute hemorrhagic transformation (HT). The Wnt/β-catenin signaling pathway plays an important role in regulating blood-brain barrier (BBB) formation central nervous system. We explored whether glucagon-like peptide-1 receptor (GLP-1R) agonist exendin-4 (EX-4) reduces risk of HT rtPA treatment via using a rat transient middle cerebral artery...

10.1007/s12035-022-02811-9 article EN cc-by Molecular Neurobiology 2022-03-31

10.1007/s11596-008-0121-x article EN Journal of Huazhong University of Science and Technology [Medical Sciences] 2008-02-01

The present study aimed to evaluate the feasibility, safety, and efficacy of laparoscopic “core-pulling” salpingectomy for tubal pregnancy. Laparoscopic core-pulling is a novel minimally invasive variant, whose technical details are described here. In this retrospective study, 154 patients with pregnancy underwent salpingectomy. total, 76 78 (LCPS) conventional multiport (MPLS), respectively. Then, clinical characteristics, intraoperative findings, operative outcomes were compared between 2...

10.9738/intsurg-d-15-00072.1 article EN International Surgery 2019-05-01

Objective To investigate the clinical therapeutic effect of integrative treatment model and damage control theory in severe multiple injury. Methods A retrospective study was done on 116 patients with injuries who were divided into plus group, group conventional group. The relationship correlative factors mortality rate among three groups compared before operation, during operation after operation. Results All indices better than other two lower (P<0.05). Conclusions Early use can obviously...

10.3760/cma.j.issn.1001-8050.2009.09.267 article EN Zhonghua chuangshang zazhi 2009-09-15

Objective To investigate the efficacy of emergency vacuum sealing drainage (VSD) in treatment crush syndrome. Methods A total 102 patients with injury were randomly screened out and divided into VSD group (n = 50), delayed 22) control 30). The variances indices syndrome after between three groups analyzed. Results vital sign, urine volume, laboratory examination results improved incidence rate syndrome, complications mortality significantly decreased than those (P < 0.05). For complications,...

10.3760/cma.j.issn.1001-8050.2009.02.30 article EN Zhonghua chuangshang zazhi 2009-02-15
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