A5001393393- Urinary Bladder and Prostate Research
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Renal cell carcinoma treatment
- Urological Disorders and Treatments
- Urologic and reproductive health conditions
- Urinary Tract Infections Management
- Urinary and Genital Oncology Studies
- Hormonal and reproductive studies
- Immunotherapy and Immune Responses
- Multiple and Secondary Primary Cancers
- Cancer Cells and Metastasis
- Cancer Immunotherapy and Biomarkers
- Helicobacter pylori-related gastroenterology studies
- Liver Disease Diagnosis and Treatment
- Genital Health and Disease
- Hepatitis C virus research
- Colorectal Cancer Screening and Detection
- Renal and related cancers
- Pediatric Urology and Nephrology Studies
- Renal and Vascular Pathologies
- Organ Transplantation Techniques and Outcomes
- Colorectal Cancer Surgical Treatments
- Pancreatic and Hepatic Oncology Research
Inje University Busan Paik Hospital
2016-2025
Sahmyook Medical Center
2005-2024
Inje University Haeundae Paik Hospital
2023
Inje University
2004-2022
Busan Medical Center
2013-2018
Stanford University
2018
Government of the Republic of Korea
2016
Seoul National University Bundang Hospital
2008-2011
Seoul National University
2009
The Korean Urological Oncology Society
2006
Abstract During development, the formation of a mature, well-functioning heart requires transformation ventricular wall from loose trabecular network into dense compact myocardium at mid-gestation. Failure to is associated in humans with congenital diseases such as left non-compaction (LVNC). The mechanisms regulating myocardial compaction are however still poorly understood. Here, we show that deletion Ino80 chromatin remodeler vascular endothelial cells prevents developing mouse heart....
We present an unusual renal tumor, which has not been classified under a known subtype of cell carcinoma (RCC) and characteristically shows similar histology to thyroid follicular carcinoma. The patient was 32-year-old asymptomatic woman who found have kidney mass during her annual physical examination. She had no lesions in the ultrasound examinations, there abnormal function test. Neither mediastinal nor ovarian abnormalities were observed. resected showed well-defined nodular tumor...
Reducing the risk of urethral strictures after transurethral surgery for patients with bladder cancer requires effective strategies. We compared clinical outcomes a novel drug-injectable catheter set (NIUS) hyaluronic acid (HA) those conventional intraurethral HA injection method. This six-center, prospective, randomized, single-blind trial included 192 male aged ≥ 20 years scheduled to undergo surgery. The primary outcome was patient-reported satisfaction. Secondary were pain intensity,...
The present study aimed to evaluate the incidence, characteristics and management of hepatic immune‑related adverse events (irAEs) in patients with advanced or metastatic urothelial carcinoma (UC) renal cell (RCC) receiving immune checkpoint inhibitors (ICIs). Data regarding demographics, ICI regimens irAEs from 213 UC RCC ICIs between February 2018 September 2023 at three tertiary medical centers (Inje University Busan Paik Hospital, Busan, South Korea; Dongnam Institute Radiological...
.The Sustainable Development Goals (SDGs) aim to provide a framework for addressing global environmental, political and socio-economic challenges, with the third goal focusing on ensuring healthy lives promoting wellbeing all [1]. The SDG emphasizes need achieving Universal Health Coverage (UHC) while health inequities, particularly among most vulnerable populations It advocates comprehensive access various services all, including preventive, curative rehabilitative However, five years away...
Colonoscopy training programs and the minimal experience with colonoscopy required to be considered technically competent are not well established. The aim of this study was determine learning curves factors associated difficult procedure at a single center.A total 3,243 colonoscopies were performed by 12 first-year gastroenterology fellows, various clinical assessed prospectively for 22 months. Acquisition competence (success rate) evaluated based on two objective criteria: (i) adjusted...
Purpose:To investigate the incidence of benign prostatic hyperplasia (BPH) in Korea and treatment patterns for 3 years after diagnosis a nationwide database.Materials Methods: We created cohort patients diagnosed BPH between 2007 2011 from Health Insurance Review & Assessment database, database reimbursement.The was defined as having (N40.0 International Classification Diseases, 10th revision) primary or secondary ≥2 times 2008.The 2008 calculated.Treatment were determined months interval...
Abstract Background: Serology is widely used for epidemiologic research of Helicobacter pylori . However, there limited information on the long‐term follow up H. titers after eradication. In addition, it presumed that reinfection rate decreases as infection decreases. The aim this study was to investigate IgG, and evaluate in Korea. Methods: Among 247 patients, who were enrolled during 2003–07, 185 patients with invasive test positive received proton pump inhibitor‐based triple therapy,...
Background: Although the PSA test has been used in Korea for over 20 years, incidence of prostate cancer risen, and associated mortality increased about 13-fold 20-year period. Also, several investigators have suggested that Asians America are more likely to present with advanced than Caucasians. We compared characteristics native Koreans Americans (Caucasians African-Americans) undergoing radical prostatectomies US. Materials Methods: Study subjects comprised patients at Korean US hospitals...
OBJECTIVES: To evaluate the clinical features, treatments, stages, and survival in older adults with hepatocellular carcinoma (HCC). DESIGN: A consecutive case study retrospective medical record review. SETTING: University hospital (tertiary referral center) Korea. PARTICIPANTS: Two hundred sixty-two participants HCC diagnosed between May 1, 2003, December 31, 2006. MEASUREMENTS: Clinical characteristics, four staging systems for HCC, (≥65, n=113) younger (<65, n=149) people HCC. RESULTS:...
Prostate-specific antigen (PSA) is used for diagnosing prostate cancer, but does not reflect the characteristics of cancer cells to allow assessment progression. PSA mRNA and circulating tumor (CTCs) could be potential biomarkers. However, relationship between serum levels in CTCs unclear, this study aimed investigate relationship.Healthy donors (HD, n = 9), patients with local non-metastatic stage (n 30), metastatic hormone-sensitive (mHSPC, 10), castration-resistant (mCRPC, 75), were...
We encountered 2 cases of mucinous tubular and spindle cell carcinoma (MTSCC) during a short time. In 61-year-old man who had macroscopic hematuria for 1 month, the 14.5 × 14.0 12.0-cm resected tumor involved right middle aspect renal parenchyma compressed pelvis. an asymptomatic 47-year-old man, was found annual physical examination. The 3.5 3.0 2.0-cm located at upper pole kidney. histologic findings in both were similar. Tumors consisted tightly packed, small, elongated tubules separated...
Swallowing is a rare cause of neurally mediated syncope. The mechanism swallow syncope that contributes to hypotension, bradycardia, or both complex. A 59-year-old man had experienced recurrent loss consciousness during swallowing carbonated beverages sticky foods. Another complained intermittent just after eating These two patients no significant structural functional abnormalities in the esophagus heart. Both cases showed bradycardia when lower was stretched by balloon inflation....
Lymphocyte-activation gene 3 (LAG-3) represents a potential immune checkpoint target for cancer treatment. We investigated LAG-3 expression and its prognostic value in patients with surgically treated clear cell renal carcinoma (RCC) correlated programmed death ligand 1(PD-L1).We evaluated PD-L1 using immunohistochemistry on tissue microarrays incorporating 134 primary excision specimens of RCC (ccRCC). The were analyzed as two groups: the whole cohort those metastatic (mRCC). genome atlas...
The University of California, San Francisco, announced in 2011 Cancer the Prostate Risk Assessment Postsurgical (CAPRA-S) score which included pathologic data, but there were no results for comparing preoperative predictors with CAPRA-S score. We evaluated validation our institution and compare result progression predictor, CAPRA Data 130 patients reviewed who underwent radical prostatectomy localized prostate cancer from 2008 to 2013. Performance predicting free probabilities was assessed...
Abstract We aimed to isolate circulating tumor cells (CTCs) using a microfluidic technique with novel lateral magnetophoretic microseparator. Prostate cancer–specific gene expressions were evaluated mRNA from the isolated CTCs. A CTC‐based multigene model was then developed for identifying advanced prostate cancer. Peripheral blood samples obtained five healthy donors and patients localized cancer (26 cases), metastatic hormone‐sensitive (mHSPC, 10 castration‐resistant (mCRPC, 28 cases). CTC...
Abstract Purpose: Prostate-specific membrane antigen (PSMA)–based images, which visually quantify PSMA expression, are used to determine prostate cancer micrometastases. This study evaluated whether a circulating tumor cell (CTC)–based transcript platform, including mRNA, could help identify potential prognostic markers in cancer. Experimental Design: We prospectively enrolled 21 healthy individuals and 247 patients with [localized (LPCa), n = 94; metastatic hormone–sensitive (mHSPC), 44;...
This study aims to investigate the trend in medical travel by non-Seoul residents Seoul for treatment of prostate cancer and also possible factors affecting trend.This represents a retrospective cohort using data from theKoreanNationalHealth Insurance System 2002 2015. Annual trends were produced proportions patients who traveled according age group, economic status types treatment. Multiple logistic analysiswas used determine surgeries at facilities among residents.A total 68,543 defined as...
A complete enumeration study was conducted to evaluate trends in national practice patterns and direct medical costs for prostate cancer (PCa) Korea over a 10-year retrospective period using data from the Korean National Health Insurance Service.Reimbursement records 874,924 patients diagnosed between 2002 2014 with primary PCa according International Classification of Disease (ICD) 10th revision code C61 were accessed. To assess newly after 2005, 68,596 managed January 2005 31 December...
We conducted the screening of sexually transmitted infections to define prevalence genital Chlamydia trachomatis and Neisseria gonorrhoeae status sexual risk behavior among homeless adolescents (10-19 yr old) in Korea. Adolescents who ran away from home are under care youth shelters ten cities Korea served as study population. Participants filled out a self-administered questionnaire related sexuality. First-void urine was analyzed for chlamydial gonococcal infection by strand displacement...
To compare the current management of benign prostatic hyperplasia (BPH) by urologists and nonurologists use Korean nationwide health insurance data. We obtained patient data from national system. New patients diagnosed with BPH in 2009 were divided into two groups depending on whether they a urologist (U group) or nonurologist (NU group). A total 390,767 individuals newly 2009. Of these, 240,907 (61.7%) U group 149,860 (38.3%) NU group. The rate all initial evaluation tests, except serum...