A5100696128- Intracranial Aneurysms: Treatment and Complications
- Tissue Engineering and Regenerative Medicine
- Vascular Malformations Diagnosis and Treatment
- Nerve injury and regeneration
- Mesenchymal stem cell research
- Traumatic Brain Injury and Neurovascular Disturbances
- Head and Neck Surgical Oncology
- Immune Response and Inflammation
- Sarcoma Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Spinal Cord Injury Research
- Educational Reforms and Innovations
- Cancer Mechanisms and Therapy
- Head and Neck Cancer Studies
- Immune cells in cancer
- Nasal Surgery and Airway Studies
- Moyamoya disease diagnosis and treatment
- Neurosurgical Procedures and Complications
- Spinal Fractures and Fixation Techniques
- Heme Oxygenase-1 and Carbon Monoxide
- Endometrial and Cervical Cancer Treatments
- Liver physiology and pathology
- Treatment of Major Depression
- Aortic aneurysm repair treatments
Heilongjiang Provincial Hospital
2024
Union Hospital
2024
Huazhong University of Science and Technology
2020-2024
Dalian University of Technology
2023
Dalian Municipal Central Hospital
2020-2023
People's Hospital of Xinjiang Uygur Autonomous Region
2021
Tongji Hospital
2020
Dalian Medical University
2020
Sun Yat-sen Memorial Hospital
2019
Sun Yat-sen University
2019
As a new member of the vasculoprotective gasotransmitter family, hydrogen sulfide (H2S) functions similar to nitric oxide (NO) and carbon monoxide (CO). Endothelial cell (EC) death autophagy enable cells cope with progression cardiovascular diseases. However, impacts underlying mechanisms H2S in autophagic process ECs are not completely understood. Here, we investigated effects on human vascular ECs.Human umbilical vein endothelial (HUVECs) were exposed different concentrations (0, 50, 100,...
Abstract Amniotic epithelial cells (AECs) were reported to show a neuroprotective effect on neurons, but there was no direct evidence for functional relationship between neural stem (NSCs) and AECs. The aim of this study determine whether AECs could stimulate differentiation expand neurogenesis NSCs, the roles due diffusible factor or required cell‐cell contact. isolated from rat amnion E14–16 NSCs neocortical tissue. growth compared under different conditions. results showed that cultured...
Abstract Extracellular matrix is the gold standard for tissue regeneration. In this study, we directly made extracellular of or organ into scaffold spinal cord injuries, a strategy that seldomly tried in engineering. The aim study was to determine if chemically extracted acellular muscle could be potential injury. implanted lateral hemisected adult rat thoracic cord. Control rats were similarly injured. After 1 and 4 weeks, integration biocompatibility, axon sprouting, myelination evaluated....
Abstract Bridging strategies are essential for spinal cord repair in order to provide a physical substrate allowing axons grow across the site of lesions. In this study, we have evaluated therapeutic effects adding amniotic epithelial cells unidirectionally oriented acellular muscle scaffold and compared with effect alone. Chemically extracted muscles, or without cells, were implanted into lateral hemisected adult rat thoracic cord. Control rats similarly injured. After 4 weeks, scaffolds...
The aim of this study was to investigate the safety and efficacy transarterial chemoembolization sorafenib (TACE-S) combined with microwave ablation (TACE-S-MWA) for treatment patients advanced primary hepatocellular carcinoma (HCC).Between January 2015 December 2018, 152 consecutive HCC patients, who underwent TACE-S-MWA (MWA group, n=77) or TACE-S (Non-MWA n=75), were investigated. Overall survival (OS), time progression (TTP) compared between two groups. Prognostic factors analyzed using...
Study Design. A computed tomographic assessment. Objective. To establish morphometric data of sacral-2 alar iliac (S2AI) screw fixation in pediatric population. Summary Background Data. Studies on parameters S2AI are mostly based adult The scoliosis also needs the fixation, however, without previous information among Methods. Computed tomography (CT) scans 120 patients spinal deformities obtained and imported to Mimics software for 3D reconstruction. Then, a cylinder (radius 3.25 mm) is...
This paper presents the findings of an observational study involving 38 patients to evaluate application a surgical technique utilizing autologous costal cartilage scaffold for correcting nasal tip and alar asymmetry in unilateral cleft lip-nasal deformity. Nasal septum extension spreader grafts (SEG) warped batten grafts, both made from cartilage, were utilized open rhinoplasty procedures. The graft was fixed caudal end SEG, with lower lateral on side suspended free part newly created lift...
Abstract Head and neck squamous cancer (HNSC) is a heterogenous malignant tumour disease with poor prognosis has become the current major public health concern worldwide. Oral cell carcinoma (OSCC) majority of HNSC. It still in lack comprehensive immune microenvironment analysis prognostic model development for OSCC's clinic practice. Single‐cell sequencing data was conducted to identify subtypes illustrate cell–cell interaction status OSCC via R package ‘Seurat’, ‘Harmony’, ‘elldex’...
Our previous research has shown that seeding amniotic epithelial cells (AECs) in chemically extracted acellular muscle scaffold (CEAMC) better promotes the functional recovery of spinal cord injury (SCI) than alone. However, massive death transplanted cells, which is related to early inflammatory response, still a problem cell therapy. study proved nordihydroguaiaretic acid (NDGA) inhibits inflammation after SCI. In this study, we tested strategy combining administration NDGA and...
Objective To evaluate the therapeutic effect of endovascular embolization using Guglielmi detachable coils(GDCs)or electrolytically coils(EDCs)for early treatment ruptured intracranial aneurysms. Methods A total 208 patients with 220 intraeranial aneurysms were treated in emergency setting GDCs or EDCs after aneurysm rupture. Results All successfully embelized coils.Complete embolization(>95%)of was achieved 128 eases,and 80%-95%embolization 80 cases,with other 12 having an partial less than...
Objective To explore the effect of naloxone (NLX) on patients with severe head injury and herniation brain after craniotomy. Methods A total 108 were divided into 2groups: NLX group was treated general therapy control only by The abnormal respiration heartbeat, recovery consciousness at early period prognosis later observed all data analyzed statistically. Results heartbeat significantly less in than first 7d injury(P<0.01). More revived 14d 1month (P<0.05). better that 3months Conclusion...