A5067482210- Air Quality and Health Impacts
- Occupational and environmental lung diseases
- Carcinogens and Genotoxicity Assessment
- Occupational exposure and asthma
- Occupational Health and Safety Research
- Health, Environment, Cognitive Aging
- Chemical Safety and Risk Management
- Electromagnetic Fields and Biological Effects
- Radiation Dose and Imaging
- Cancer Risks and Factors
- Smoking Behavior and Cessation
- Global Cancer Incidence and Screening
- Energy and Environment Impacts
- Heavy Metal Exposure and Toxicity
- Indoor Air Quality and Microbial Exposure
- Health disparities and outcomes
- Climate Change and Health Impacts
- Meningioma and schwannoma management
- Alcohol Consumption and Health Effects
- Reliability and Agreement in Measurement
- Colorectal Cancer Screening and Detection
- Radioactivity and Radon Measurements
- Environmental Justice and Health Disparities
- Air Quality Monitoring and Forecasting
- Noise Effects and Management
Université de Montréal
2015-2024
Centre Hospitalier de l’Université de Montréal
2012-2023
Institut National de la Recherche Scientifique
2000-2020
Canadian Cancer Society
2017-2018
Cancer Research Society
2012-2018
Institute of Social and Preventive Medicine
2018
Ottawa Hospital
2017
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
2017
Public Health Ontario
2017
Cancer Care Ontario
2017
Lung cancer is mainly caused by smoking, but the quantitative relations between smoking and histologic subtypes of lung remain inconclusive. By using one largest datasets ever assembled, we explored impact on risks major cell types cancer. This pooled analysis included 13,169 cases 16,010 controls from Europe Canada. Studies with population comprised 66.5% subjects. Adenocarcinoma (AdCa) was most prevalent subtype in never smokers women. Squamous carcinoma (SqCC) predominated male smokers....
The method of data collection in household health surveys can be a major determinant cost and quality. A survey strategy comprise mail, telephone, or home interview methods, individually combination to follow up non-respondents. purpose this study Montreal was compare quality various strategies. Strategies which began with mail telephone contact, followed by the two other provided response rates as high (all between 80 90 per cent), for one-half interviews when used sole method. rate higher...
The occupational environment has been a most fruitful one for investigating the etiology of human cancer. Many recognized carcinogens are carcinogens. There is large volume epidemiologic and experimental data concerning cancer risks in different work environments. It important to synthesize this information both scientific public health purposes. Various organizations individuals have published lists However, such limited by unclear criteria which should be considered carcinogens,...
BACKGROUND: This project directly and empirically measured the level of gastrointestinal (GI) illness related to consumption tapwater prepared from sewage-contaminated surface waters meeting current water quality criteria. METHODS: A randomized intervention trial was carried out; 299 eligible households were supplied with domestic filters (reverse-osmosis) that eliminate microbial chemical contaminants their water, 307 left usual without a filter. The GI symptomatology evaluated by means...
Wood dust is one of the oldest and most common occupational exposures in world. The present analyses examine effect lifetime exposure to wood diverse settings on lung cancer risk. We conducted two population-based case–control studies Montreal: Study I (1979–1986) included 857 cases sets controls (533 population 1349 controls), II (1996–2001) comprised 736 894 controls. Detailed job histories were obtained by interview each was evaluated expert chemist–hygienists estimate likelihood level...
The objective of this study was to assess if drinking water meeting currently accepted microbiological standards is the source gastrointestinal illnesses and attempt identify source(s) these illnesses. A randomized prospective conducted over a period 16 months (September 1993-December 1994) in middle class suburban community served by single filtration plant. representative sample 1400 families were selected randomly allocated four groups 350, following regimens: (1) tap water; (2) from...
(2003). Rejoinder: Reanalysis of the Harvard Six Cities Study and American Cancer Society Particulate Air Pollution Mortality. Journal Toxicology Environmental Health, Part A: Vol. 66, No. 16-19, pp. 1715-1722.
The very rapid worldwide increase in mobile phone use the last decade has generated considerable interest possible health effects of exposure to radio frequency (RF) fields. A multinational case-control study, INTERPHONE, was set-up investigate whether increases risk cancer and, more specifically, RF fields emitted by phones are carcinogenic. study focused on tumours arising tissues most exposed from phones: glioma, meningioma, acoustic neurinoma and parotid gland tumours. In addition a...
The role of occupational substances as stomach carcinogens has not been well investigated. In 1979, a population-based case-control study was undertaken in Montreal to explore the possible association between hundreds circumstances and several cancer sites, including stomach. total, 250 male patients with pathologically confirmed cancer, 2,289 controls cancers at other 533 were interviewed obtain detailed job histories relevant data on potential confounders. Job evaluated by expert chemists...
Epidemiologic research often involves the simultaneous assessment of associations between many risk factors and several disease outcomes. In such situations, designed to generate hypotheses, multiple univariate hypothesis-testing is not an appropriate basis for inference. The number true positive in a collection can be estimated by comparing observed distribution p values theoretical uniform distribution, or negative associations, empiric randomization distribution. None these approaches,...
Heavy industrial exposure to asbestos causes lung cancer and mesothelioma, but it remains unknown whether much lower environmental also these cancers. Nevertheless, regulatory agencies, including the Environmental Protection Agency (EPA), have assessed risk of by extrapolating known risks from past today's levels (roughly 100,000 times lower). We tested EPA's model for predicting asbestos-induced in a population women with relatively high nonoccupational asbestos.
Mall and telephone survey methods, with or without follow-up by other are cost-effectIve alternatives to the conventional home interview approach. However, It has long been thought that they especially susceptible nonresponse bias. The study addressed this issue in context of parallel mall health surveys carried out Montreal. strategy among 1,555 adults achieved 68.5% response increased 80.9%. Respondents were adequately representative entire sample respect socioeconomic status, number...
From the assessment of statistical interaction between risk factors it is tempting to infer nature biologic factors. However, use analyses epidemiologic data processes can be misleading. as an example, we consider multistage model carcinogenesis. Under this model, shown, by means simple hypothetical examples, that even if carcinogenic act independently, some pairs may fit additive a multiplicative and neither. The elucidation biological interactions models requires imaginative prudent...
Rationale: Diesel motor exhaust is classified by the International Agency for Research on Cancer as probably carcinogenic to humans. The epidemiologic evidence evaluated limited because most studies lack adequate control potential confounders and only a few have reported exposure–response relationships.Objectives: Investigate lung cancer risk associated with occupational exposure diesel exhaust, while controlling confounders.Methods: SYNERGY project pooled information lifetime work histories...
Baumgarten, M., J. Slemlatyckl (Instltut Armand-Frappler, Laval-des-Rapldes, Quebec H7V 1B7, Canada) and G. W. Glbbs. Validity of work histories obtained by interview for epldemlologlc purposes. Am J Epidemiol 1983;118:583–91. Many epidemiologic studies the relationship between occupation disease depend on job from study subjects. A validation was undertaken to determine accuracy interview, examine whether certain characteristics respondents design influence reporting accuracy. For 297...
An association between low socioeconomic status (SES) and lung cancer has been observed in several studies, but often without adequate control for smoking behavior. We studied the occupationally derived SES, using data from international pooled SYNERGY study.
Previous respiratory diseases have been associated with increased risk of lung cancer. Respiratory conditions often co-occur and few studies investigated multiple simultaneously.
The Monographs produced by the International Agency for Research on Cancer (IARC) apply rigorous procedures scientific review and evaluation of carcinogenic hazards independent experts. Preamble to IARC Monographs, which outlines these procedures, was updated in 2019, following recommendations a 2018 expert advisory group. This article presents key features Preamble, major milestone that will enable take advantage recent procedural advances made during 12 years since last amendments....
Background: Recently, the International Agency for Research on Cancer (IARC) Programme Evaluation of Carcinogenic Risks to Humans has been criticized several its evaluations, and also approach used perform these evaluations. Some critics have claimed that failures IARC Working Groups recognize study weaknesses biases Group members led inappropriate classification a number agents as carcinogenic humans.Objectives: The authors this Commentary are scientists from various disciplines relevant...
Evidence is limited regarding risk and the shape of exposure-response curve at low asbestos exposure levels. We estimated for occupational assessed joint effect smoking by sex lung cancer subtype in general population studies.