A5100515273- Immune Cell Function and Interaction
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory viral infections research
- T-cell and B-cell Immunology
- Media Influence and Health
- Cytomegalovirus and herpesvirus research
- Inflammation biomarkers and pathways
- Advanced biosensing and bioanalysis techniques
- Vaccine Coverage and Hesitancy
- Microbial Natural Products and Biosynthesis
- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Nosocomial Infections in ICU
- Intracerebral and Subarachnoid Hemorrhage Research
- Pneumonia and Respiratory Infections
- Adipokines, Inflammation, and Metabolic Diseases
- Retinal Imaging and Analysis
- Pediatric health and respiratory diseases
- Fungal Biology and Applications
- Advanced Photocatalysis Techniques
- Influenza Virus Research Studies
- Misinformation and Its Impacts
- Advanced Computational Techniques and Applications
- Pregnancy-related medical research
- Meat and Animal Product Quality
Fudan University
2011-2025
University of South China
2023-2025
Wuyi University
2024-2025
Affiliated Hospital of Nantong University
2023-2024
Nantong University
2023-2024
Collaborative Innovation Center of Chemical Science and Engineering Tianjin
2024
Peking University People's Hospital
2022-2024
Yunnan University
2023-2024
Peking University
2022-2024
Xi'an Shiyou University
2024
During the spring of 2013, a novel avian-origin influenza A (H7N9) virus emerged and spread among humans in China. Data were lacking on clinical characteristics infections caused by this virus.Using medical charts, we collected data 111 patients with laboratory-confirmed infection through May 10, 2013.Of studied, 76.6% admitted to an intensive care unit (ICU), 27.0% died. The median age was 61 years, 42.3% 65 years or older; 31.5% female. total 61.3% had at least one underlying condition....
Abstract Background The cytotoxicity of NK cells is largely dependent on IgG Fc receptor CD16a, which mediates antibody-dependent cell-mediated (ADCC). high-affinity and non-cleavable CD16 (hnCD16) developed demonstrated a multi-tumor killing potential. However, the hnCD16 activates single signal provides limited tumor suppression. How to exploit properties incorporate cell-specific activation domains promising development direction further improve anti-tumor activity cells. Methods To...
Use of antibiotics in outpatients with community-acquired pneumonia (CAP) is empirical, which may lead to overuse and selection pressure for resistance. Procalcitonin (PCT) levels predict the severity CAP be used guide antibiotic use hospitalized patients. This study evaluated value PCT measurements guiding low-risk CAP.This was a randomized intervention trial conducted between February 2005 December 2008 that included 172 consecutive patients suspected CAP, whom 156 completed study. The...
Abstract Sub-high temperature Daqu, a traditional solid fermenting agent used in Chinese strong-aroma Baijiu production, is abundant diverse microorganisms, including bacteria, yeasts, molds, and actinomycetes. Among these, yeasts are pivotal for ethanol production flavor formation. However, counting Daqu challenging due to interference from molds bacteria. Antibiotics employed inhibit bacterial growth, but there no practical way suppress without affecting the growth of yeasts. In this...
Cerebral amyloid angiopathy (CAA) is recognized as a major contributor to progressive cognitive decline and cerebral hemorrhages in the elderly population. Currently, there global shortage of safe effective treatments for this condition. Bisdemethoxycurcumin (BDMC) has been demonstrated exhibit pharmacological effects with anti-Aβ toxicity properties. Thus, present study mainly focused on potential therapeutic BDMC CAA. The 30 male C57BL/6 mice were subjected chronic treatment five vascular...
Functional membranes with waterproof, breathable, and thermal regulation capabilities are increasingly sought after across various industries. However, developing such functional commonly involves complex multi-step preparation processes. Herein, we introduced perfluorodecyltriethoxysilane (FAS) into the poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP) solution for one-step electrospinning, successfully fabricating that combine these properties. The hydrophobicity of PVDF-HFP/FAS...
Evaluating the role of IL-6 and CD4+/CD8+ in predicting prognosis elderly patients with acute exacerbations chronic obstructive pulmonary disease (AECOPD). This study retrospectively enrolled 413 who were hospitalized for AECOPD between January 2019 December 2021. Patients divided into event non-event groups based on whether they readmitted or died due to during 18 months follow-up. The associations adverse events assessed using Cox proportional hazards regression models, Kaplan-Meier...
BackgroundThe world's first reported patient infected with avian influenza H7N9 was treated at the Fifth People's Hospital of Shanghai. Shortly thereafter, several other cases emerged in local area. Here, we describe detailed epidemiological and clinical data 6 H7N9. Methods FindingsWe analyzed epidemiologic from clustered patients Minhang District Shanghai during a 2-week period. Of patients, 2 were single family. In addition, 3 had history contact poultry; however, all lived proximity food...
This randomized controlled trial aimed to evaluate whether the serum procalcitonin (PCT) level can be utilized guide use of antibiotics in treatment acute exacerbations asthma. A total 293 consecutive patients with suspected asthma attacks from February 2005 July 2010 participated this study. 225 completed Serum PCT levels, and other inflammatory biomarkers all were measured. In addition standard treatment, control group received according attending physicians' discretions, while treated...
Air pollution can be a contributing cause to the development and exacerbation of coronary heart disease (CHD), but there is little knowledge about acute effects air on different clinical subtypes CHD.We conducted time-series study investigate association (particulate matter with an aerodynamic diameter < 10 µm [PM10], sulfur dioxide [SO2], nitrogen [NO2]) emergency department (ED) visits due five CHD in Shanghai, China, from 2010 2012. We applied over-dispersed Poisson generalized addictive...
Several studies have investigated the relationship between vitamin D (VD) and its receptors (VDR) risk of cervical cancer.However, underlying mechanisms that underpin these associations remain incompletely comprehended.In this review, we analyzed impacts VD VDR on cancer related mechanisms, discussed effects VD, calcium, other vitamins cancer.Our literature research found their signaling pathways played indispensable roles in occurrence progression cancer.Epidemiological established VDR,...
Microorganisms possess a strong capacity for secondary metabolite synthesis, which is represented by tightly controlled networks. The absence of any enzymes leads to change in the original metabolic pathway, with decrease or even elimination synthetic product, not permissible under conditions normal life activities microorganisms. In order improve efficiency metabolism, organisms have evolved multifunctional (MFEs) that can catalyze two more kinds reactions via multiple active sites....