A5060368209- Liver Disease and Transplantation
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Ferroptosis and cancer prognosis
- Gallbladder and Bile Duct Disorders
- Crystallization and Solubility Studies
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Venous Thromboembolism Diagnosis and Management
- Organ Transplantation Techniques and Outcomes
- X-ray Diffraction in Crystallography
- Pancreatic and Hepatic Oncology Research
- Vascular Procedures and Complications
- Head and Neck Cancer Studies
- Lung Cancer Research Studies
- Vascular Anomalies and Treatments
- Cardiac Imaging and Diagnostics
- Gastric Cancer Management and Outcomes
- Genetic and Kidney Cyst Diseases
- Circular RNAs in diseases
- Renal and Vascular Pathologies
- Cancer, Lipids, and Metabolism
- Cancer Immunotherapy and Biomarkers
- Pediatric Hepatobiliary Diseases and Treatments
Fudan University
2013-2024
Zhongshan Hospital
2013-2024
Jinshan Hospital of Fudan University
2022-2024
Heilongjiang University of Chinese Medicine
2024
First Affiliated Hospital of Zhengzhou University
2024
Shanghai Institute of Hematology
2018-2023
National Clinical Research Center for Digestive Diseases
2023
The First Affiliated Hospital, Sun Yat-sen University
2007-2021
Sun Yat-sen University
2007-2021
National Clinical Research
2020
Purpose . The aim of this study was to evaluate the safety and efficacy transcatheter arterial embolization (TAE) in patients with renal hemorrhage after percutaneous nephrolithotomy (PCNL) risk factors that may result severe bleeding requiring TAE. Methods We retrospectively reviewed 121 post-PCNL hemorrhage. Thirty-two receiving endovascular were compared 89 only conservative treatment. demographic clinical data recorded between two groups. values estimated glomerular filtration rate...
Abstract Increasing evidence shows that circular RNAs (circRNAs) play a regulatory role in cancer. In the present study, we aimed to investigate characteristics and effects of hsa_circ_0026134 hepatocellular carcinoma (HCC). We investigated expression 20 pairs clinical tissues from HCC patients; different cell lines; effect on proliferation invasion mechanisms interactions among hsa_circ_0026134, miR-127-5p, tripartite motif-containing protein 25 (TRIM25) insulin-like growth factor 2...
Ginsenoside Rg3 (Rg3), extracted from the root of Panax ginseng, is one most abundant ginsenosides. exhibits anticancer activity in various cancer models vitro and vivo by modulating several signaling pathways, such as those phosphatidylinositol 3-kinase, epidermal growth factor receptor, mitogen-activated protein kinases, p53, nuclear kappa-B, reactive oxygen species. Besides, can be used adjunctive with conventional therapies, enhancing therapeutic effects reversing drug resistance...
Objective: To investigate the safety and efficacy of radiofrequency ablation combined with transarterial chemoembolization in patients specially located small hepatocellular carcinoma. Materials Methods: Between March 2014 2017, a total 26 lesions (10 perivascular, 6 subdiaphragmatic, 5 subcapsular, subdiaphragmatic location; mean diameter 2.12 (0.62) cm), who received ablation–transarterial treatment, were retrospectively analyzed. Local tumor response was assessed by computed...
Background Stent occlusion by tumor ingrowth or overgrowth is the main cause of jaundice recurrence after metal stent insertion in patients with malignant obstructive (MOJ). The application intraluminal brachytherapy (ILBT) MOJ results local control tumors, which prolong patency. Purpose To evaluate safety ILBT pig bile ducts using ribbons iodine-125 ( 125 I) seeds. Material and Methods Sixteen healthy pigs were randomly assigned to four groups each. A I seed ribbon was implanted into common...
Radiofrequency ablation (RFA) is widely used in palliative therapy of malignant cancers. Several studies have shown its applicability and safety for locally advanced pancreatic cancer (LAPC). The objective this study was to modify the current regimen improve therapeutic effect.Immune cell subtypes related cytokines were quantified uncover immune pattern changes post-RFA treatment. Then, high-throughput proteome analysis performed identify differentially expressed proteins associated with...
Objective: To evaluate the effects of addition preoperative hepatic and regional arterial chemotherapy (PHRAC) on prognosis stage II III colorectal cancer (CRC) in a multicenter setting. Summary Background Data: Our previous single-center pilot trial suggested that PHRAC combination with surgical resection could reduce occurrence liver metastasis (LM) improve survival CRC patients. Methods: A prospective multi-center randomized controlled was conducted from December 2008 to 2012 at 5...
This study aimed to investigate the idarubicin loading method, compatible stability with contrast agent, release profiles, and morphological properties of 50–150, 100–300, 300–500 μm CalliSpheres®. The amounts added, medium, condition, drug concentration were investigated as factors influencing efficiency. rate was negatively correlated amount added diameter CalliSpheres® positively concentration. Compared in purified water incubation at room temperature, 5% glucose, heating, ultrasound...
Abstract Background RNA 3’-terminal phosphate cyclase-like protein (Rcl1) is involved in pre-rRNA processing, but its implication cancers remains unclear. Methods RCL1 expressions 21 malignancies was examinated through GEPIA website portal. Clinical data related to level Hepatocellular Carcinoma (HCC) samples were downloaded TCGA, ICGC, GEO databases. Survival analysis and gene function enrichment analyses performed R software. The correlation between expression tumor immune infiltration...
The long noncoding RNAs (lncRNAs) play the important role in tumor occurrence and progression, epithelial to mesenchymal transition (EMT) is critical process for migration. However, of EMT-related lncRNA hepatocellular carcinoma (HCC) has not been elucidated. In this study, we selected lncRNAs HCC by using data from Cancer Genome Atlas database (TCGA). Two prognostic models overall survival (OS) relapse-free (RFS) were constructed validated through Cox regression model, Kaplan-Meier...
Hepatocellular carcinoma (HCC) is the most common malignancy in liver, with a poor prognosis. Transmembrane protein 209 (TMEM209) involves multiple biological processes, such as substance transportation and signal transduction, abundantly expressed tumor tissues. However, relationship between TMEM209 HCC has not been comprehensively elucidated. In this study, we aimed to illustrate issue by vitro vivo experiments. Bioinformatic analysis clinical sample validation revealed that was...
Background Hepatic encephalopathy after transjugular intrahepatic portosystemic shunt (TIPS) remains an unsolved problem; therefore, this study aimed to compare the efficacy of shunting different portal vein branch during TIPS with 8 mm covered stent for preventing gastroesophageal variceal rebleeding in cirrhotic patients. Methods Between November 2015 and December 2018, medical records consecutive patients who received were analyzed retrospectively. Shunting left right branches was...
To retrospectively analyze the safety and efficacy of mechanical thrombectomy combined with pharmacologic thrombolysis to treat non-acute symptomatic portal vein thrombosis (PVT) using an intrahepatic portosystemic shunt (IPS) assisted by percutaneous transhepatic approach.From April 2006 May 2012, 18 patients PVT were treated balloon dilation, sheath-directed thrombus aspiration continuous infusion urokinase IPS approach. The significance differences in gradient measured before after...