A5042547974- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Nonlinear Optical Materials Studies
- Hepatitis C virus research
- Nonlinear Optical Materials Research
- Porphyrin and Phthalocyanine Chemistry
- Liver Disease and Transplantation
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Crystallography and molecular interactions
- Liver physiology and pathology
- Hepatitis Viruses Studies and Epidemiology
- Photochromic and Fluorescence Chemistry
- Luminescence and Fluorescent Materials
- Photochemistry and Electron Transfer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Diseases and Immunity
- GDF15 and Related Biomarkers
- Systemic Lupus Erythematosus Research
- Organic Electronics and Photovoltaics
- HIV/AIDS drug development and treatment
- Diet, Metabolism, and Disease
- Drug-Induced Hepatotoxicity and Protection
- Pancreatic and Hepatic Oncology Research
- Advanced Fiber Laser Technologies
Capital Medical University
2009-2025
Beijing Friendship Hospital
2010-2025
National Clinical Research Center for Digestive Diseases
2020-2025
XinHua Hospital
2024
Shanghai Jiao Tong University
2024
Chinese PLA General Hospital
2024
Huzhou University
2023-2024
National Institute of Diabetes and Digestive and Kidney Diseases
2019-2023
ProQuest (United States)
2019-2023
Harbin Institute of Technology
2020-2022
•This is the first prospective validation of Baveno VII recompensation definition in patients with HBV-related cirrhosis.•A stable improvement liver function tests was defined as MELD <10 and/or ALB & INR TBIL within Child-Pugh A.•On-treatment scores may be more predictive probability than baseline scores.•Prompt antiviral therapy effective for cirrhosis, even under severe conditions. Background AimsAntiviral improves clinical outcomes chronic hepatitis B (CHB), including those cirrhosis. In...
Hepatitis D virus (HDV) infection occurs as a coinfection with hepatitis B and increases the risk of hepatocellular carcinoma, decompensated cirrhosis, mortality compared to (HBV) monoinfection. Reliable estimates prevalence HDV disease burden are essential formulate strategies find coinfected individuals more effectively efficiently. The global HBV infections was estimated be 262,240,000 in 2021. Only 1,994,000 were newly diagnosed 2021, than half new diagnoses made China. Our initial...
Abstract Background The Asia–Pacific (AP) region carries a substantial burden of HBV. Affordable HBV treatment is crucial to attain WHO’s elimination goal. This study assesses the pricing and affordability in AP. Methods A survey conducted among APASL members from 2 Aug 30 Oct, 2023, gathered data on antiviral drugs, costs covering stages chronic hepatitis B (CHB), compensated cirrhosis (CC), hepatocellular carcinoma (HCC), liver transplant, monitoring expenses. Drug for TDF ETV were...
Abstract Aims This study aims to determine the predictive capability for metabolic dysfunction‐associated steatohepatitis (MASH) long before its diagnosis by using six previously identified diagnostic biomarkers steatotic liver disease (MASLD) with proteomic data from UK Biobank. Materials and Methods A nested case–control comprising a MASH group three age‐ sex‐matched control groups (metabolic steatosis, viral hepatitis normal controls) was conducted. Olink proteomics, anthropometric...
Intramolecular charge transfer (ICT) is an important factor in the nonlinear optical (NLO) properties of organic molecules. In order to study effect ICT on two-photon absorption (TPA) and excited-state (ESA), three chalcone derivatives (1, 2 3) with different electron push-pull systems were designed synthesized. The performance these depends mainly includes ultrafast femtosecond time domain long-lived state (CTS) picosecond domain, which dominate molecular TPA ESA respectively. Hole-electron...
Six analogous two-dimensional (2D) [Tp*WS3Cu3]-based (Tp* = hydridotris(3,5-dimethylpyrazol-1-yl)borate) networks, namely, {[(Tp*WS3Cu3)2L3](μ3-N3)}n (2: L 5-methyltetrazolate (Mtta); 3a: 5-ethyltetrazolate (Etta)) and {[(Tp*WS3Cu3)2L3]BF4}n (3b: Etta; 4: 5-propyltetrazolate (Ptta); 5: 5-butyltetrazolate (Btta); 6: 5-pentyltetrazolate (Petta)) were synthesized by reactions of [Et4N][Tp*WS3] (1), [Cu(CH3CN)4]BF4, NaN3, NH4BF4 in different nitrile solvents (CH3(CH2)nCN, n 0, 1, 2, 3, 4) under...
Two simple hydrazone derivatives (A1 and A2) linked with different Π-conjugated systems are designed synthesized to reach ultrafast broad-band optical limiting (OL) under pulse widths. To exploit various virtues of two-photon absorption (TPA)-induced excited-state (TPA–ESA), ESA is successfully established on a singlet state. Both compounds show range from 556 750 nm relatively long lifetime. A1 displays larger reverse saturable than A2 in the multiwavelength Z-scan experiments. Furthermore,...
We report a case of 62-year old woman admitted to our hospital for multiple nodular metastatic liver lesions found by ultrasonography in regular medical examination.Routine laboratory tests were normal.PET-CT showed bone and lesions.Liver biopsy revealed infiltration myeloma with positive staining kappa light chain.Further investigation marrow aspiration, immunofixation immunoelectrophoresis serum protein, urine test Bence-Jones β2-microglobulin confirmed the diagnosis.The patient also...
Hypercoagulability, hemodynamic changes, and endothelial injury are the three major contributors to development of thrombosis. However, role hypercoagulability in portal vein thrombosis (PVT) liver cirrhosis is still controversial. The aim this study elucidate relationship between procoagulant imbalance PVT patients with cirrhosis.This included 151 (n=20) or without (n=131). Levels factor (FVIII) anticoagulants [protein C (PC), protein S (PS), antithrombin (AT)] were measured. Procoagulant...