- Meat and Animal Product Quality
- Animal Nutrition and Physiology
- Biochemical effects in animals
- Fungal Infections and Studies
- Immunodeficiency and Autoimmune Disorders
- Tuberculosis Research and Epidemiology
- Macrophage Migration Inhibitory Factor
- Cancer Immunotherapy and Biomarkers
- Probiotics and Fermented Foods
- Drug-Induced Adverse Reactions
- Urticaria and Related Conditions
- Lung Cancer Treatments and Mutations
- Stress Responses and Cortisol
- Infectious Diseases and Mycology
- Advanced Proteomics Techniques and Applications
- Autoimmune and Inflammatory Disorders Research
- Colorectal Cancer Treatments and Studies
- Antifungal resistance and susceptibility
- Occupational and environmental lung diseases
- Mechanisms of cancer metastasis
- Actinomycetales infections and treatment
- Hemoglobin structure and function
- Plasma Applications and Diagnostics
- Phytoplasmas and Hemiptera pathogens
- Livestock and Poultry Management
State Key Laboratory of Electrical Insulation and Power Equipment
2024
Beijing Academy of Agricultural and Forestry Sciences
2023-2024
Xi'an Jiaotong University
2024
Chinese PLA General Hospital
2024
Guangxi Medical University
2012-2021
First Affiliated Hospital of GuangXi Medical University
2012-2020
Formononetin is a main active component of red clover plants (Trifolium pratense L.), and considered as phytoestrogen. Our previous studies demonstrated that formononetin caused cell cycle arrest at the G0/G1 phase by inactivating insulin-like growth factor 1(IGF1)/IGF1R-phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) pathway in MCF-7 cells. In present study, we investigated molecular mechanisms involved effect on prostate cancer results suggested higher concentrations inhibited...
This study aimed to investigate the effects of dietary crude protein (CP) and lysine levels on growth performance, slaughter meat quality, myofiber characteristics slow-growing chicken. A 3 × factorial experiment was arranged, chickens were fed with CP (16.0%, 17.0%, 18.0%) (0.69%, 0.84%, 0.99%). total 540 8-week-old Beijing-You Chicken (BYC) female growing randomly allocated 9 groups, 5 replicates per group, 12 replicate. The birds one experimental diets. Growth determined at 16 weeks age....
Unique metabolites contribute to the performance of meat flavor and potential function. In this study, UHPLC-Q Exactive HF-X-based metabolomics multivariate analysis were applied explore characteristic in breast Beijing-You chicken (BYC) aged 150, 300, 450 days (D150, D300, D450). Based on criteria variable importance projection (VIP) > 1
Chicken age contributes to the meat characteristics; however, knowledge regarding pathways and proteins associated with quality muscle development are still scarce, especially in chicken thigh meat. Hence, objective of this study was elucidate intricate relationship between these traits by liquid chromatography mass spectrometry at three different ages. A total 341 differential expressed (DEPs) were screened out (fold change ≥ 1.50 or ≤0.67 p < 0.05) among 45 samples (15 per age) Beijing-You...
The physical properties, free amino acids, and metabolites of Beijing-You chicken (BYC) breast meat aged 90, 120, 150 days were analyzed to investigate the flavor changes with age. shear force intramuscular fat increased from 90 120 significantly. contents total acids essential decreased No significant differences detected between days. sweet bitter umami showed no different ages. In addition, GC-MS LC-MS integrated for metabolite detection in meat. A 128, 142, 88 differential identified...
The study aimed to investigate the effects of woody breast (WB) condition on chemical compositions in broiler Pectoralis fillets during 3-day marination and after cooking. Broiler (18 normal 18 severe WB) were marinated 3 marinade solutions (with a 25 g/100 g meat ratio): 0.625 sodium tripolyphosphate/100 (P), 5 NaCl/100 (S), or NaCl + (SP), along with non-marinated control (C). Contents (moisture, protein, collagen, salt) measured at successive sampling points: D0 (pre-marinating), D1 (24-h...
Tumor-infiltrating immune cells (TICs) play a central role in the tumor microenvironment, which can reflect host anti-tumor response. However, few studies have explored TICs predicting prognosis of lung adenocarcinoma (LUAD). In our study, we enrolled 2470 LUAD patients from TCGA and GEO databases, normalized enrichment scores for 65 cell types were quantified each patient. An immune-related risk score (IRRS) was built on basis 17 selected using LASSO regression analysis, results showed that...
As the only two You-chicken breeds in China, Baicheng-You (BCY) and Beijing-You (BJY) chickens are famous for their good meat quality. However, so far, molecular basis of germplasm is not yet clear. The genetic relationship among BCY, BJY, European-origin broilers (BRs) was analyzed using whole genome resequencing data to contribute this issue. A total 18,852,372 single nucleotide polymorphisms (SNPs) were obtained study. After quality control, 8,207,242 SNPs applied subsequent analysis....
This study evaluated the potential of using combined relaxation (CRelax) spectra within time-domain nuclear magnetic resonance (TD-NMR) measurements to predict meat quality. Broiler fillets affected by different severities wooden breast (WB) conditions were used as case-study samples because broader ranges meat-quality variations. Partial least squares regression (PLSR) models established water-holding capacity (WHC) and texture, demonstrating superior CRelax capabilities for predicting...