A5100701467- Hydrology and Sediment Transport Processes
- Hydraulic flow and structures
- Infective Endocarditis Diagnosis and Management
- COVID-19 Clinical Research Studies
- Ecology and Conservation Studies
- Venous Thromboembolism Diagnosis and Management
- Mycobacterium research and diagnosis
- SARS-CoV-2 and COVID-19 Research
- Bacterial Identification and Susceptibility Testing
- Diphtheria, Corynebacterium, and Tetanus
- Acute Myeloid Leukemia Research
- Antifungal resistance and susceptibility
- Acute Ischemic Stroke Management
- Agriculture, Soil, Plant Science
- SARS-CoV-2 detection and testing
- Streptococcal Infections and Treatments
- Soil erosion and sediment transport
- Infection Control in Healthcare
- Tuberculosis Research and Epidemiology
- Blood disorders and treatments
- Environmental and Sediment Control
- Hydrology and Watershed Management Studies
- Radiomics and Machine Learning in Medical Imaging
- Multiple Myeloma Research and Treatments
- Heparin-Induced Thrombocytopenia and Thrombosis
Seoul National University Hospital
2006-2024
Dongguk University
2024
Seoul National University
2008-2023
Kangdong Sacred Heart Hospital
2022
University of Ulsan
2022
Asan Medical Center
2022
Ulsan College
2022
Boramae Medical Center
2020
Inje University
2013-2018
Armed Forces Capital Hospital
2017-2018
Positive results from real-time reverse-transcription polymerase chain reaction (rRT-PCR) in recovered patients raise concern that who recover coronavirus disease 2019 (COVID-19) may be at risk of reinfection. Currently, however, evidence supports reinfection with severe acute respiratory syndrome 2 (SARS-CoV-2) has not been reported.We conducted whole-genome sequencing the viral RNA clinical specimens initial infection and positive retest 6 COVID-19 retested for SARS-CoV-2 via rRT-PCR after...
In managing patients with coronavirus disease 2019 (COVID-19), early identification of those at high risk and real-time monitoring progression to severe COVID-19 is a major challenge. We aimed identify potential prognostic protein markers expand understanding proteome dynamics during clinical the disease. performed in-depth profiling on 137 sera, longitudinally collected from 25 (non-severe patients, n = 13; who progressed COVID-19, 12). identified 11 biomarkers, including novel IGLV3-19...
Background: Inflammatory stimuli can induce neutrophils to release nuclear DNA combined with histones into the extracellular space, forming neutrophil traps. Because inflammation contributes diabetic retinopathy, it is plausible that trap formation actively occurs in retinopathy. This case-control study investigated clinical relevance of circulating levels components as risk factors and further evaluated whether glucose induced vitro using whole blood from healthy volunteers. Methods:...
Cell Population Data (CPD) provides various blood cell parameters that can be used for differential diagnosis. analytics using Machine Learning (ML) have been playing a pivotal role in revolutionizing medical diagnostics. This research presents novel approach of ML algorithms screening hematologic malignancies CPD. The data collection was done at Konkuk University Medical Center, Seoul. A total (882 cases: 457 malignancy and 425 non-malignancy) were analysis. In our study, seven machine...
In the coronavirus disease 2019 (COVID-19) pandemic era, simultaneous detection of severe acute respiratory syndrome 2 (SARS-CoV-2), influenza virus (Flu), and syncytial (RSV) is important in rapid differential diagnosis patients with symptoms. Three multiplex real-time reverse transcription polymerase chain reaction (rRT-PCR) assays have been recently developed commercially Korea: PowerChek™ SARS-CoV-2, Influenza A&B Multiplex Real-time PCR Kit (PowerChek; KogeneBiotech); STANDARD™ M...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern have been emerging. However, knowledge temporal and spatial dynamics SARS-CoV-2 is limited. This study characterized evolution in immunosuppressed patients with long-term shedding for 73–250 days, without specific treatment. We conducted whole-genome sequencing 27 serial samples, including 26 samples collected from various anatomic sites two the first positive sample patient 2's mother. analysed intrahost...
Thirteen phenolic compounds from Aloe barbadensis (syn. A. vera) and arborescens were analysed by high performance liquid chromatography, using a reverse phase column eluted with methanol: water gradient, detected UV at 293 nm. Aloesin, 8-C-glucosyl-7-O-methyl-(S)-aloesol, neoaloesin A, 8-O-methyl-7-hydroxyaloin A B, 10-hydroxyaloin isoaloeresin D, aloin aloeresin E aloe-emodin barbadensis: aloenin, aloenin arborescens, identified quantified. The seasonal variation of two species was also...
<b><i>Background:</i></b> The Effect of Cilostazol in Acute Lacunar Infarction Based on Pulsatility Index the Transcranial Doppler (ECLIPse) study showed a significant decrease transcranial (TCD) pulsatility index (PI) with cilostazol treatment at 90 days after acute lacunar infarction. aim present was to perform subgroup analysis ECLIPse order explore effect infarction based cerebral white matter hyperintensities (WMH) volume....
Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) is widely used in clinical microbiology laboratories because it cost-effective, reliable, and fast. This study aimed at comparing the identification performance recently developed Autof ms1000 (Autobio, China) with that Bruker Biotyper (Bruker Daltonics, Germany). From January to June 2020, 205 preserved strains 302 isolates were for comparison. Bacteria tested duplicates direct transfer method,...
We investigated mortality and predictors of due to intensive care unit-associated candidemia (ICUAC) versus non-ICUAC by Candida species. This study included all cases in 11 hospitals from 2017 2018 South Korea. The all-cause rates 370 patients with ICUAC were approximately twofold higher than those 437 at 7 days (2.3-fold, 31.1%/13.3%), 30 (1.9-fold, 49.5%/25.4%), 90 57.8%/30.9%). Significant species-specific associations 7- 30-day ICUAC-associated not observed. Multivariate analysis...
Several studies reported that severe acute respiratory syndrome coronavirus-2 antibody levels change over 6 months in participants receiving the vaccination. From enrolled 272 health care workers (HCWs), blood samples were obtained at 2, 16, and 24 weeks after second vaccination dose. In 267 noninfected HCWs, neutralizing antibodies decreased by 23.9%, anti-spike/receptor binding domain 53.8% weeks. We observed no significant difference reduction between sexes; however, younger individuals,...
There have been reports of increases in the incidence and prevalence nontuberculous mycobacterial pulmonary disease (NTM-PD) several countries, but no studies analyzed claims data using laboratory tests. This study aimed to estimate nationwide epidemiology medical treatments NTM-PD according tests run Korea.Using from Health Insurance Review Assessment Service, we patients with mycobacterium (ICD-10: A31) who were diagnosed Jan 2007 Jun 2019. The whether related performed analyzed....
Although blood transfusion is fundamental throughout the course of hematologic malignancies, acute myeloid leukemia (AML) patients requiring intensive chemotherapy are left at edges patient management programs because current guidelines do not have established recommendations for red cell (RBC) threshold in treated hematological disorders with anemia and accompanied severe thrombocytopenia. To provide answers trigger doses ideal RBC such situation, we conducted this prospective randomized...
Lophomonas blattarum is an anaerobic protozoan living in the intestine of cockroaches and house dust mites, with ultramicroscopic characteristics such as presence a parabasal body, axial filament, absence mitochondria. More than 200 cases infection respiratory tract have been reported worldwide. However, current diagnosis depends only on light microscopic morphological findings from secretions. In this study, we attempted to provide more robust evidence protozoal immunocompromised patient...
Abstract Background It is challenging to diagnose brucellosis in nonendemic regions because it a nonspecific febrile disease. The accurate identification of Brucella spp. clinical microbiology laboratories (CMLs) continues pose difficulties. Most reports misidentification are for B. melitensis , and we report rare case misidentified abortus . Case presentation A 67-year-old man visited an outpatient clinic complaining fatigue, fever, weight loss. patient had history slaughtering cows with...
When to perform echocardiography rule out infective endocarditis (IE) in patients with viridans group streptococci (VGS) bloodstream infections (BSIs) is unclear.
While fungal infections cause considerable morbidity and mortality, the performance of current diagnostic tests for infection is low. Even though metagenomics or targeted next-generation sequencing have been investigated various clinical samples, real-time utility these methods still needs to be elucidated. In this study, we used internal transcribed spacer (ITS) D1-D3 ribosomal DNA nanopore amplicon metagenomic assess its in patients with infections. Eighty-four samples from seventy-three...
Importance Whether COVID-19 contributes to youth-onset diabetes is controversial, and research in Asia lacking. Objective To explore the incidence severity of among youths during pandemic South Korea. Design, Setting, Participants This cohort study used claims data for January 1, 2017, through February 28, 2022, from National Health Insurance Service database The type 1 (T1D) 2 (T2D) patients younger than 20 years was analyzed compared with that prepandemic period. included incident cases...
최근에 불투수층의 증가로 인하여 지표면의 저류량이 감소하고 첨두유출과 전체 지표면유출은 증가하고 있다. 첨두유출량의 증가와 빠른 도달시간으로 도시유역의 홍수 피해가 또한 토양으로 침투되는 강우량이 감소하여 지하수위가 하강한다. 그러므로 도시하천의 건천화가 진행되어 유역의 물 순환이 악화된다. 따라서 본 연구에서는 건천화 문제를 감소시킬 수 있는 방안중 하나인 투수성 포장의 침투실험을 통하여 투수효과를 정량적으로 분석 및 평가하였다. SWMM 모형을 창원천 남천 유역에 적용하여 침투실험에서 얻어진 투수계수를 이용하여 물순환 영향을 분석하였다. Recently, due to increase of the impervious layer, storage surface layer has been reduced. Otherwise peak runoff and total have raised. Because larger amount rapid time concentration, flood...