A5100340643- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Calcium Carbonate Crystallization and Inhibition
- Collagen: Extraction and Characterization
- Tissue Engineering and Regenerative Medicine
- Molecular Sensors and Ion Detection
- 3D Printing in Biomedical Research
- RNA Interference and Gene Delivery
- biodegradable polymer synthesis and properties
- Marine Biology and Environmental Chemistry
- Periodontal Regeneration and Treatments
- Aquaculture disease management and microbiota
- Inorganic Chemistry and Materials
- Pickering emulsions and particle stabilization
- Magnesium Alloys: Properties and Applications
- Orthopaedic implants and arthroplasty
- bioluminescence and chemiluminescence research
- Sulfur Compounds in Biology
- Graphene and Nanomaterials Applications
- Nanoplatforms for cancer theranostics
- Advanced biosensing and bioanalysis techniques
- Dental materials and restorations
- Dental Implant Techniques and Outcomes
- Spine and Intervertebral Disc Pathology
- Titanium Alloys Microstructure and Properties
Texas A&M University
2022-2024
Zhengzhou University
2024
University of Missouri
2024
Peking University
2020-2023
Fuzhou University
2017-2022
Guangdong Academy of Medical Sciences
2021
Guangdong Provincial People's Hospital
2021
Hefei Institutes of Physical Science
2021
High Magnetic Field Laboratory
2021
Chinese Academy of Sciences
2021
Abstract Development of artificial biomaterials by mimicking extracellular matrix bone tissue is a promising strategy for regeneration. Hydrogel has emerged as type viable substitute, but its inhomogeneous networks and weak mechanics greatly impede clinical applications. Here, dual crosslinked gelling system developed with tunable architectures to promote osteogenic capacity. Polyhedral oligomeric silsesquioxane (POSS) designated rigid core surrounded six disulfide‐linked PEG shells two...
As key characteristic molecules, several H2S-activated probes have been explored for colon cancer studies. However, a few ratiometric fluorescence (FL) with NIR-II emissions reported the quantitative detection of H2S in vivo. Here, we developed an situ H2S-activatable nanoprobe two emission signals and intelligently lighting up cancer. The comprised down conversion nanoparticle (DCNP), which emitted FL at 1550 nm on irradiation 980 laser (F1550Em, 980Ex). Further, human serum albumin (HSA)...
Abstract Destructive periodontitis destroys alveolar bone and eventually leads to tooth loss. While guided regeneration, which is based on creating a physical barrier hinder the infiltration of epithelial connective tissues into defect sites, has been widely used for its outcomes remain variable. In this work, multifunctional nanofibrous hollow microsphere (NFHMS) developed enhanced regeneration. The NFHMS first prepared via combining double emulsification thermally induced phase separation...
Abstract Numerous bioactive molecules produced in cells are involved the process of bone formation. We consider that appropriate, simultaneous application two types would accelerate regeneration tissues and organs. Therefore, we combined aspirin‐loaded liposomes (Asp@Lipo) forming peptide‐1 (BFP‐1) on three dimensional‐printed polycaprolactone (PCL) scaffold determined whether this system improved outcomes. vitro experiments indicated Asp@Lipo/BFP‐1at a 3:7 ratio was best option for...
Abstract Primary malignant bone tumors can be life-threatening. Surgical resection of tumor plus chemotherapy is the standard clinical treatment. However, postoperative recovery hindered due to recurrence caused by residual cells and defect tissue. Herein, a multifunctional mussel-inspired film was fabricated on Mg alloy, that is, an inner hydrothermal-treated layer, middle layer polydopamine, outer doxorubicin. The modified alloy showed excellent photothermal effect thermal/pH-controlled...
Neurovascularized bone regeneration remains an enormous challenge in the clinic.
MicroRNAs (miRNAs) play a pivotal role in regulating gene expression and are considered new molecular targets bone tissue engineering. However, effective delivery of miRNAs to the defect areas transfection into osteogenic progenitor cells has been an obstacle application. In this work, miRNA-218 (miR-218) was used as miRNA regulator, multifunctional peptide-conjugated carrier poly(lactide-co-glycolide)-g-polyethylenimine-b-polyethylene glycol-R9-G4-IKVAVW (PPP-RGI) developed condense with...
Highly interconnected porous structure and bionic mechanical performance are important challenges to the successful fabrication of small-diameter vascular scaffolds. This article describes an effective approach prepare outer inner tubular poly(ε-caprolactone) (PCL)/polylactic acid (PLA) scaffolds by ultrasonic irradiation (UI)-assisted supercritical CO2 (scCO2) microcellular foaming technology. The pore structures, properties, cytocompatibility investigated with respect introduction UI at...