A5018818276- Autopsy Techniques and Outcomes
- Forensic and Genetic Research
- Sleep and Wakefulness Research
- COVID-19 Clinical Research Studies
- Hormonal and reproductive studies
- Diet and metabolism studies
- Sleep and related disorders
- Hemophilia Treatment and Research
- Platelet Disorders and Treatments
- MicroRNA in disease regulation
- SARS-CoV-2 and COVID-19 Research
- Heart Rate Variability and Autonomic Control
- Heparin-Induced Thrombocytopenia and Thrombosis
- COVID-19 and healthcare impacts
- Forensic Anthropology and Bioarchaeology Studies
- Regulation of Appetite and Obesity
- Adipose Tissue and Metabolism
- Forensic Entomology and Diptera Studies
- Pharmacogenetics and Drug Metabolism
- Attention Deficit Hyperactivity Disorder
- Long-Term Effects of COVID-19
- Adipokines, Inflammation, and Metabolic Diseases
- Transcranial Magnetic Stimulation Studies
- Dietary Effects on Health
- Cardiac electrophysiology and arrhythmias
University of Catania
1980-2025
University of Foggia
2014-2024
Federico II University Hospital
2021
University of Naples Federico II
2019-2021
University of Campania "Luigi Vanvitelli"
2020
Università degli Studi di Enna Kore
2020
Ospedale G.F. Ingrassia
2020
Azienda Ospedaliero Universitaria Ospedali Riuniti
2019
Istituti di Ricovero e Cura a Carattere Scientifico
1987-2004
Casa Sollievo della Sofferenza
2004
Abstract Hand grip strength is a widely used proxy of muscular fitness, marker frailty, and predictor range morbidities all-cause mortality. To investigate the genetic determinants variation in strength, we perform large-scale discovery analysis combined sample 195,180 individuals identify 16 loci associated with ( P <5 × 10 −8 ) analyses. A number these contain genes implicated structure function skeletal muscle fibres ACTG1 ), neuronal maintenance signal transduction PEX14, TGFA, SYT1...
Adipose tissue is a multifunctional organ involved in many physiological and metabolic processes through the production of adipokines and, particular, adiponectin. Caloric restriction one most important strategies against obesity today. The very low-calorie ketogenic diet (VLCKD) represents type caloric with or extremely low daily food energy consumption. This study aimed to investigate effects VLCKD on anthropometric biochemical parameters such as adiponectin levels, well analyzing...
The ketogenic diet (KD), a high in fat and protein but low carbohydrates, is gaining much interest due to its positive effects, especially neurodegenerative diseases. Beta-hydroxybutyrate (BHB), the major ketone body produced during carbohydrate deprivation that occurs KD, assumed have neuroprotective although molecular mechanisms responsible for these effects are still unclear. Microglial cell activation plays key role development of diseases, resulting production several proinflammatory...
The term artificial intelligence (AI) was coined in the 1950s and it has successfully made its way into different fields of medicine. Forensic sciences AI are increasingly intersecting that hold tremendous potential for solving complex criminal investigations. Considering great evolution technologies applied to forensic genetics, this literature review aims explore existing body research investigates application field genetics. Scopus Web Science were searched: after an accurate evaluation,...
The purpose of this study was to determine the relationship between personality, serotonin transporter (5HTT) polymorphisms and occurrence anxiety depressive symptoms in elite athletes. 133 healthy participants completed NEO Five-Factor Inventory (NEO-FFI). mood states were assessed using Profile Mood States (POMS) questionnaire. athlete's mental skills through Sport Performance Psychological (IPPS-48). psychiatric personality disorders Clinical Interview for DSM-IV Disorders. A polymerase...
Scope: The hypothalamus is a key brain region involved in the control of feeding and energy expenditure. Hypothalamic inflammation oxidative stress are landmarks both obesity aging processes, although molecular mechanisms still unknown. Therefore, with aim to understand neurobiological homeostasis during aging, we evaluate effects long high-fat diet (HFD) rats, at different age, on modulation hypothalamic pathway, stress, inflammation. Procedures: Male Wistar rats were divided into two...
Abstract “Touch DNA” is DNA obtained from biological material transferred a donor to an object or person during physical contact. This particular kind of evidence could play essential role in forensic laboratory work and considered important tool for investigators. Even though the principal aspects have been extensively studied, date, there are few reports research field retrieval garments that worn. study aimed investigate “handling time”, analyzing particularly minimum contact time...
Caloric restriction is a valid strategy to reduce the visceral adipose tissue (VAT) content in obese persons. Hypocretin-1 (orexin-A) neuropeptide synthesized lateral hypothalamus that strongly modulates food intake, thus influencing accumulation. Therapeutic diets obesity treatment may combine advantages of caloric and dietary ketosis. The current study aimed evaluate effect very low calorie ketogenic diet (VLCKD) population patients.Adiposity parameters orexin-A serum profiling were...
Traumatic brain injury (TBI) is one of the leading causes death and disability worldwide. Our understanding its pathobiology has substantially increased. Following TBI, following occur, edema formation, swelling, increased intracranial pressure, changes in cerebral blood flow, hypoxia, neuroinflammation, oxidative stress, excitotoxicity, apoptosis. Experimental animal models have been developed. However, difficulty mimicking human TBI explains why few neuroprotective strategies, drawn up on...
(1) Background: The current outbreak of COVID-19 infection is an ongoing challenge and a major threat to public health that requires surveillance, prompt diagnosis, as well research efforts understand the viral pathogenesis. Despite this, date, very few studies have been performed concerning autoptic specimens. Therefore, this study aimed: (i) reiterate importance examination, only method able precisely define cause death; (ii) provide complete post-mortem histological immunohistochemical...
The current challenge worldwide is the administration of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines. Even if rarely, severe vascular adverse reactions temporally related to vaccine have induced diffidence in population at large. In particular, researchers are focusing on so-called “thrombosis and thrombocytopenia after COVID-19 vaccination”. This study aims establish a practical workflow define relationship between events following immunization (AEFI)...
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BACKGROUND Reduced cardiac vagal tone in patients with myocardial infarction (MI) is associated a high risk of sudden death. Muscarinic blocking agents small doses induce paradoxical increase activity normal subjects. We tested whether low scopolamine delivered transdermally enhance tonic and reflex the acute phase MI. METHODS AND RESULTS Patients were randomized to (n = 17) or placebo patch 19) double-blind fashion 4.20 +/- 0.18 days after Cardiac was assessed by testing arterial baroreflex...