Joanna Malukiewicz
A5061723805- Primate Behavior and Ecology
- Amphibian and Reptile Biology
- Genomics and Phylogenetic Studies
- Wildlife Ecology and Conservation
- Gut microbiota and health
- Identification and Quantification in Food
- Genetic diversity and population structure
- Aquaculture disease management and microbiota
- Chromosomal and Genetic Variations
- Molecular Biology Techniques and Applications
- Species Distribution and Climate Change
- Clostridium difficile and Clostridium perfringens research
- Evolution and Paleontology Studies
- Mycobacterium research and diagnosis
- Mosquito-borne diseases and control
- Tuberculosis Research and Epidemiology
- Pleistocene-Era Hominins and Archaeology
- Bat Biology and Ecology Studies
- HIV Research and Treatment
- Diptera species taxonomy and behavior
- Insect behavior and control techniques
- Genetic and phenotypic traits in livestock
- Forensic Entomology and Diptera Studies
- Genomic variations and chromosomal abnormalities
- Yersinia bacterium, plague, ectoparasites research
Universität Hamburg
2024-2025
German Primate Center
2019-2025
Universidade de São Paulo
2019-2024
Instituto de Medicina Avançada
2022
Broad Institute
2020-2021
Instituto de Medicina Tropical
2020
Arizona State University
2012-2019
Universidade Federal de Viçosa
2015-2019
Universidade Federal do Vale do São Francisco
2019
Kent State University
2006
Progress in genome sequencing now enables the large-scale generation of reference genomes. Various international initiatives aim to generate genomes representing global biodiversity. These provide unique insights into genomic diversity and architecture, thereby enabling comprehensive analyses population functional genomics, are expected revolutionize conservation genomics.
Abstract The most dynamic and repetitive regions of great ape genomes have traditionally been excluded from comparative studies 1–3 . Consequently, our understanding the evolution species is incomplete. Here we present haplotype-resolved reference analyses six species: chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan siamang. We achieve chromosome-level contiguity with substantial sequence accuracy (<1 error in 2.7 megabases) completely 215 gapless chromosomes...
We present haplotype-resolved reference genomes and comparative analyses of six ape species, namely: chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran siamang. achieve chromosome-level contiguity with unparalleled sequence accuracy (<1 error in 500,000 base pairs), completely sequencing 215 gapless chromosomes telomere-to-telomere. resolve challenging regions, such as the major histocompatibility complex immunoglobulin loci, providing more in-depth evolutionary insights. Comparative...
Animal hybridization is well documented, but evolutionary outcomes and conservation priorities often differ for natural anthropogenic hybrids. Among primates, an order with many endangered species, the two contexts can be hard to disentangle from one another, which carries important implications. Callithrix marmosets give us a unique glimpse of genetic effects under distinct human-induced contexts. Here, we use 44 autosomal microsatellite marker panel examine genome-wide admixture levels...
ABSTRACT Hybridization is continually documented in primates, but effects of natural and anthropogenic hybridization on biodiversity are still unclear differentiating between these contexts remains challenging regards to primate evolution conservation. Here, we examine the mitochondrial DNA (mtDNA) control region Callithrix marmosets, which provide a unique glimpse into interspecific mating under distinct conditions. was sampled from 40 marmosets along 50‐km transect previously...
Mammalian captive dietary specialists like folivores are prone to gastrointestinal distress and primate suffer the greatest gut microbiome diversity losses in captivity compared wild. Marmosets represent another group of specialists, exudivores that eat plant exudates, but whose remains relatively less studied. The common occurrence marmosets prompted us study Callithrix composition predictive function through bacterial 16S ribosomal RNA V4 region sequencing. We sampled 59 wild across four...
Over a century after two introduced pathogens decimated American chestnut populations, breeding programs continue to incorporate resistance from Chinese recover self-sustaining populations. Due complex genetics of blight resistance, it is challenging obtain trees with sufficient and competitive growth. We developed high quality reference genomes for leveraged large disease phenotype genotype datasets develop accurate genomic selection. Inoculation simulation results indicate that may be...
Gene expression differences are shaped by selective pressures and contribute to phenotypic between species. We identified 964 copy number (CNDs) of conserved sequences across three primate species examined their potential effects on gene profiles. Samples with different genes had significantly than samples neutral number. Genes encoding regulatory molecules differed in were associated significant differences. Additionally, we 127 CNDs that processed pseudogenes some which expressed....
Abstract We provide here a current overview of marmoset (Callithrix) evolution, hybridization, species biology, basic/biomedical research, and conservation initiatives. Composed 2 subgroups, the aurita group (C C flaviceps) jacchus geoffroyi, jacchus, kuhlii, penicillata), this relatively young primate radiation is endemic to Brazilian Cerrado, Caatinga, Atlantic Forest biomes. Significant impacts on Callithrix within these biomes resulting from anthropogenic activity include (1) population...
Abstract The Brazilian buffy-tufted-ear marmoset ( Callithrix aurita ), one of the world’s most endangered primates, is threatened by anthropogenic hybridization with exotic, invasive species. As there are few genetic data available for C. , we developed a PCR-free protocol minimal technical requirements to rapidly generate genomic skimming and portable nanopore sequencing. With this direct DNA sequencing approach, successfully determined complete mitogenome that initially identified as ....
Abstract Objectives Two subgroups make up the marmoset genus Callithrix . The “ aurita ” group is composed of two species, whereas evolutionary relationships among four species jacchus” remain unclear. To uncover these relationships, we first sequenced mitochondrial genomes for C. kuhlii and penicillata to complement data available congeners. We then constructed a phylogenetic tree based on mtDNA heavy chain protein coding genes from several primates untangle estimate divergence times...
Abstract In this study, we sequenced one nuclear and three mitochondrial DNA loci to construct a robust estimate of phylogeny for all available species Tetanocera. Character optimizations suggested that aquatic habitat was the ancestral condition Tetanocera larvae, there were at least parallel transitions terrestrial habitat, with reversal. Maximum likelihood analyses character state transformations showed significant correlations between changes in four larval morphological characteristics...

 The buffy-tufted-ear marmoset (Callithrix aurita) is a small primate endemic to the montane regions of southeastern Atlantic Forest in Brazil. species was formerly listed as “Vulnerable” (VU) on Brazilian Official National List Threatened Fauna Species, but December 2014 it re-classified “Endangered” (EN) result habitat loss, forest fragmentation and, especially, competition and hybridization with invasive marmosets spp.). This article gives an overview current conservation status...
Abstract Background Callithrix marmosets are a relatively young primate radiation, whose phylogeny is not yet fully resolved. These primates naturally para- and allopatric, but three species with highly invasive potential have been introduced into the southeastern Brazilian Atlantic Forest by pet trade. There, these hybridize each other endangered, native congeners. We aimed here to reconstruct robust divergence time estimates, identify biogeographic origins of autochthonous allochthonous...
We provide here a current overview of marmoset (Callithrix) evolution, hybridization, species biology, basic/biomedical research, and conservation initiatives. Composed two subgroups, the aurita group (C. C. flaviceps) jacchus geoffroyi, jacchus, kuhlii penicillata), this relatively young primate radiation is endemic to Brazilian Cerrado, Caatinga, Atlantic Forest biomes. Significant impacts on Callithrix within these biomes resulting from anthropogenic activity include: (1) population...
Zoonotic pathogens that cause leprosy (Mycobacterium leprae) and tuberculosis complex, MTBC) continue to impact modern human populations. Therefore, methods able survey mycobacterial infection in potential animal hosts are necessary for proper evaluation of exposure threats. Here we tested mycobacterial-specific single- multi-copy loci using qPCR. In a trial study which armadillos were artificially infected with M. leprae, these techniques specific sensitive pathogen detection, while more...
Gut microbiome disruptions may lead to adverse effects on wildlife fitness and viability, thus maintaining host microbiota biodiversity needs become an integral part of conservation. The highly-endangered callitrichid golden lion tamarin (GLT-Leontopithecus rosalia) is a rare conservation success, but allochthonous marmosets (Callithrix) serve as principle ecological GLT threats. However, incorporation approaches impeded by limited gut studies Brazilian primates. Here, we carried out...
ABSTRACT Mammalian captive dietary specialists like folivores are prone to gastrointestinal distress and primate suffer the greatest gut microbiome diversity losses in captivity compared wild. Marmosets represent another group of specialists, exudivores that eat plant exudates, but whose remains relatively less studied. The common occurrence marmosets prompted us study Callithrix composition predictive function through bacterial 16S ribosomal RNA V4 region sequencing. We sampled 59 wild...
Callithrix jacchus and C. penicillata are among the smallest anthropoid primates, highly specialized tree gougers, largely occupy Brazil's most extreme, semi-arid biomes. However, underlying genomic factors that underpin evolution of these species their unique traits under-investigated. Additionally, exotic populations two widely established throughout Brazil hybridize with threatened native congers. Thus, both conservation call for a better understanding evolution. Here, we applied...
During the late Pleistocene, isolated lineages of hominins exchanged genes thus influencing genomic variation in humans both past and present. However, dynamics this genetic exchange associated phenotypic consequences through time remain poorly understood. Gene across divergent can result myriad outcomes arising from these environmental conditions under which it occurs. Here we draw our collective research various organisms, illustrating some ways gene structure genomic/phenotypic diversity...