A5101572568- Traditional Chinese Medicine Studies
- Medical Research and Treatments
- Extracellular vesicles in disease
- Acute Myeloid Leukemia Research
- Prostate Cancer Treatment and Research
- Tuberculosis Research and Epidemiology
- Asthma and respiratory diseases
- Renal cell carcinoma treatment
- Renal and related cancers
- Prostate Cancer Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Mycobacterium research and diagnosis
- Diagnosis and treatment of tuberculosis
- Artificial Intelligence in Healthcare and Education
- Technology and Human Factors in Education and Health
- Livestock and Poultry Management
- Pulmonary Hypertension Research and Treatments
- Medicinal Plant Pharmacodynamics Research
- Neonatal Respiratory Health Research
- Cardiac electrophysiology and arrhythmias
- Gut microbiota and health
- Viral Infections and Immunology Research
- Acupuncture Treatment Research Studies
- Microbial Community Ecology and Physiology
- Cancer, Stress, Anesthesia, and Immune Response
Guangxi Medical University
2022-2025
Poultry Research Institute
2024-2025
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2007-2024
Shanghai University of Traditional Chinese Medicine
2007-2024
First Affiliated Hospital of GuangXi Medical University
2022
Weatherford College
2021
Liaoning University of Traditional Chinese Medicine
2008-2017
Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
2012-2017
Jilin University
2016
Xiamen University
2006-2013
The primary objective of this study was to investigate factors associated with fatigue severity in newly diagnosed patients higher-risk myelodysplastic syndromes (MDS). secondary objectives were assess symptom prevalence and examine the relationships between fatigue, quality life (QoL) overall burden these patients. analyses conducted 280 MDS Pre-treatment patient-reported evaluated Functional Assessment Chronic Illness Therapy (FACIT)-Fatigue scale QoL assessed European Organization for...
Abstract Background The introduction of multiparameter MRI and novel biomarkers has greatly improved the prediction clinically significant prostate cancer (csPCa). However, decision-making regarding biopsy prebiopsy examinations is still difficult. We aimed to establish a quick economic tool improve detection csPCa based on routinely performed clinical through an automated machine learning platform (AutoML). Methods This study included multicenter retrospective cohort two prospective cohorts...
Cancer remains a leading global cause of mortality, making early detection crucial for improving survival outcomes. The study aims to develop machine learning-enabled blood-derived exosomal RNA profiling platform multi-cancer and localization. In this multi-phase, multi-center study, we analyzed from exosomes derived peripheral blood plasma in 818 participants across eight cancer types during the discovery phase. Machine learning techniques were applied identify potential pan-cancer...
This study aims to explore the effects of spray processes with four different disinfectants on airborne culturable and pathogenic microbial concentrations, community compositions health risk assessments in chicken houses. Results indicate that compared concentrations before spraying, hypochlorous acid, glutaraldehyde-decamethonium bromide sodium dichloroisocyanate increase bacteria, fungi, Staphylococcus Candida albicans, respectively. Beyond that, have no significant concentrations. The...
The study aimed at evaluating the performance of urinary exosomal prostate-specific antigen (UE-PSA) to predict results initial prostate biopsies and discriminate clinically significant cancer (Gleason score ≥ 7, csPCa) from nonsignificant PCa < nsPCa) plus benign patients. Two hundred seventy-two consecutive participants were admitted who underwent a biopsy. UE-PSA expression was detected by enzyme-linked immunosorbent assay (ELISA). predictive power clinical value assessed receiver...
Abstract Background There are no proven tumor biomarkers for the early diagnosis of clear cell renal carcinoma (ccRCC) thus far. This study aimed to identify novel ccRCC based on exosomal mRNA (emRNA) profiling and develop emRNA-based signatures detection ccRCC. Methods Four hundred eighty-eight participants, including 226 localized ccRCCs, 73 patients with benign masses, 189 healthy controls, were recruited. Circulating emRNA sequencing was performed in 12 ccRCCs 22 controls discovery...
BACKGROUND Current prognostic systems for myelodysplastic syndromes (MDS) are based on clinical, pathologic, and laboratory indicators. The objective of the current study was to develop a new patient‐centered index patients with advanced MDS by including self‐reported fatigue severity into well‐established clinical risk classification: International Prognostic Scoring System (IPSS). METHODS A total 469 (ie, IPSS intermediate‐2 or high‐risk) were analyzed. Untreated (280 patients) recruited...
Abstract Disulfidptosis, a newly identified programmed cell death pathway in prostate cancer (PCa), is closely associated with intracellular disulfide stress and glycolysis. This study aims to elucidate the roles of disulfidptosis-related genes (DRGs) pathogenesis progression PCa, goal improving diagnostic therapeutic approaches. We analyzed PCa datasets normal tissue transcriptome data from TCGA, GEO, MSKCC. Using consensus clustering analysis LASSO regression, we developed risk scoring...
As China is one of high MDR-TB burden countries, it important to determine the drug resistant pattern and clinical characteristics multidrug tuberculosis (MDR-TB). We conducted a comprehensive nationwide study on in 17 provinces for period from June 2009 2015, total 1154 cases were finally investigated. The sought assess features contrast susceptibility profiles patients China. Cavitary disease, young age, long duration TB disease among predictors. A resistance proportion first-line drugs...
Multi-drug resistant tuberculosis (MDR-TB) is a critical global public health problem.Sputum cultures and lung images show strong association with treatment outcomes, serving as multi-dimensional approach to identify MDR-TB patients poor outcomes.The results imply that funds policy investments should be increased by early monitoring of patients, especially regarding imaging sputum bacterium. By informing physicians on changes the therapeutic schedule, outcomes can improved.
Stable angina pectoris is experienced as trans-sternal or retro-sternal pressure pain that may radiate to the left arm, neck back. Although available evidence relating its effectiveness and mechanism are weak, traditional Chinese medicine used an alternative therapy for stable pectoris. We report a protocol of randomized controlled trial using investigate effectiveness, safety patients with pectoris.This north-east Chinese, multi-center, multi-blinded, placebo-controlled superiority trail. A...
Lung cancer is a leading cause of cancer-related mortality worldwide. Currently, targeted therapy has proved highly efficient in the treatment advanced non-small cell lung (NSCLC). Mesenchymal-epithelial transition factor (MET) considered validated molecular target NSCLC. Given low incidence MET exon 14 skipping mutation, planning precision for patients clinical problem that needs to be solved. In this report, we present MET-positive case benefited from crizotinib and cabozantinib...
Abstract Unicellular marine cyanobacteria are abundant in both coastal and oligotrophic environments, where they contribute substantially to primary production. The physiological effect of future increases atmospheric CO2 concentrations on the picocyanobacteria is still poorly known. We studied changes phycocyanin (PC)-rich phycoerythrin (PE)-rich Synechococcus strains under different partial pressures (350, 600 800 ppm). PE strain showed no significant change growth rate over experimental...
Tuberculosis (TB) caused Mycobacterium tuberculosis (M.tb) is one of infectious disease that lead a large number morbidity and mortality all over the world. Although no reliable evidence has been found, it considered combining chemotherapeutic drugs with Chinese herbs can significantly improves cure rate clinical therapeutic effect. Multi-drug resistant pulmonary (MDR-PTB, n = 258) patients Qi-yin deficiency syndrome will be randomly assigned into treatment group (n 172) or control/placebo...
<title>Abstract</title> Disulfidptosis, a novel programmed cell death pathway identified in prostate cancer (PCa), is intricately linked to intracellular disulfide stress and glycolysis. This research sought elucidate the expression patterns prognostic significance of disulfidptosis-related genes (DRGs) PCa. We analyzed PCa datasets from TCGA, GEO, MSKCC, accounting for batch effects standardizing data. Using consistent cluster analysis, we categorized samples into subtypes based on 24 DRGs....
Abstract Background Healthcare workers face continuous exposure to various physiological and psychological stressors, which can lead dynamic changes in their environment potentially culminate debilitating disease. This study was conducted analyze the measures of health examination anticipate status disease risk healthcare workers. Methods A retrospective extracting data from 2018 2022 carried out. Principal component analysis (PCA) employed for unsupervised dimensionality reduction identify...
China's local chicken breeds are rich in resources, and have formed different germplasm characteristics the process of long-term selection evolution. Scientific assessment population genetic diversity identification inter-breed structure great value to protection innovative utilization breed resource. In order evaluate application effectiveness 23K SNP chip "Youxin-1" analysis chickens, we used RADseq identify genomic variation 21 developed "Youxin-1". The statistics each variety were...
This article presents a pioneering approach to enhancing underwater navigation accuracy and stealth through the utilization of gravity anomaly data. Developed by researchers from leading universities in China, study aims revolutionize autonomous marine systems unknown sea areas. By integrating advanced data processing, feature extraction, model construction, optimization techniques, cutting-edge system has been formulated, showcasing remarkable improvements precision.The core innovation lies...
Frequent exacerbations of bronchiectasis lead to poor quality life, impaired lung function, and higher mortality rates. This study aims evaluate the risk factors associated with readmission within one year due acute exacerbation (AEB). A retrospective cohort was performed on 260 patients who were hospitalized in respiratory critical care department a tertiary hospital China. Univariate multivariate Cox analyses used for year. Readmission found 44.6% bronchiectasis. The included age over 65...
Over the past two or three decades, prevalence of asthma has significantly increased worldwide; therefore, effective treatment without side effects is utmost importance. Traditional Chinese medicine (TCM) plays a vital role in reducing symptoms and improving quality life persistent-asthma patients. The aim this study to evaluate efficacy Jia Wei Yang He (JWYH) formula explore relationship between airway microbiome TCM This multicenter, parallel-arm, randomized, double-blinded,...
A model system was developed to investigate the feasibility of an integrated transportation demand management (TDM) programme in Nanhai district China by employing multi-nomial logit and nested modelling methods. Using system, impacts concerning residents' acceptance behaviour adjustments trip frequency, mode choice, departure time route choice are predicted. The study results indicate that could make a significant contribution improvement traffic conditions Nanhai. Furthermore, it is...