Isa Ashoor
A5010411354- Renal Diseases and Glomerulopathies
- Renal Transplantation Outcomes and Treatments
- Chronic Kidney Disease and Diabetes
- Pregnancy and Medication Impact
- Electrolyte and hormonal disorders
- Adolescent and Pediatric Healthcare
- Cytomegalovirus and herpesvirus research
- Vasculitis and related conditions
- Healthcare Policy and Management
- Muscle and Compartmental Disorders
- Advanced Research in Systems and Signal Processing
- Immune Cell Function and Interaction
- COVID-19 Clinical Research Studies
- Renal function and acid-base balance
- Diversity and Career in Medicine
- Complement system in diseases
- Ion Transport and Channel Regulation
- Viral-associated cancers and disorders
- Pediatric Urology and Nephrology Studies
- Organ Transplantation Techniques and Outcomes
- T-cell and B-cell Immunology
- Polyomavirus and related diseases
- Poisoning and overdose treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Birth, Development, and Health
Boston Children's Hospital
2013-2025
Harvard University
2011-2025
The Ohio State University Wexner Medical Center
2023
Louisiana State University Health Sciences Center New Orleans
2018-2022
Children's Hospital of New Orleans
2014-2021
Louisiana State University
2020-2021
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2020
University of Brescia
2020
Columbia University Irving Medical Center
2020
Children's National
2018-2019
Children with nephrotic syndrome can develop life-threatening complications, including infection and thrombosis. While AKI is associated adverse outcomes in hospitalized children, little known about the epidemiology of children syndrome. The main objectives this study were to determine incidence, epidemiology, hospital a modern cohort syndrome.Records admitted 17 pediatric nephrology centers across North America from 2010 2012 reviewed. was classified using RIFLE definition.AKI occurred...
Objective Posttransplant lymphoproliferative disorder (PTLD) is a complication of pediatric solid organ transplantation. Benign adenotonsillar lymphoid hyperplasia confounds the ability to diagnose PTLD. Our aim was identify factors that predict presence PTLD inform decision‐making regarding adenotonsillectomy. Methods The electronic medical records at quaternary children's hospital were queried over 23‐year period (2000–2023) for transplant patients underwent tonsillectomy and/or...
Pediatric nephrology is dedicated to caring for children with kidney disease, a unique blend of acute care and chronic longitudinal patient relationships. Though historically small field, trainee interest has declined over the past 2 decades. This led growing alarm about health pediatric workforce, although concerns have been hampered by lack available data enable feasible projections. article part supplement that anticipates future subspecialty workforce supply. It draws on existing...
The Cure Glomerulonephropathy Network (CureGN) is a 66-center longitudinal observational study of patients with biopsy-confirmed minimal change disease, focal segmental glomerulosclerosis, membranous nephropathy, or IgA nephropathy (IgAN), including vasculitis (IgAV). This describes the clinical characteristics and treatment patterns in cohort, comparisons between IgAN versus IgAV adult pediatric patients.Patients diagnostic kidney biopsy within 5 years screening were eligible to join...
Abstract Background There are scant data on the effect of rituximab EBV DNA levels and prevention post‐transplant lymphoproliferative disorder (PTLD) in pediatric kidney transplant recipients with DNAemia. Methods Kidney DNAemia treated to prevent PTLD between 7/1999 7/2019 at five centers were included. Those confirmed onset excluded. Primary outcomes included percentage change occurrence post rituximab. Results Twenty‐six Median age was 4 years (IQR 2.1–10.3). load monitoring by qPCR...
Background Cardiovascular disease is a major cause of morbidity and mortality in children with chronic kidney disease. We sought to determine the prevalence cardiovascular risk factors glomerular describe current practice patterns regarding factor identification management. Methods Results Seven-hundred sixty-one aged 0 17 years any 4 biopsy-confirmed primary diseases (minimal change disease, focal segmental glomerulosclerosis, membranous nephropathy, IgA nephropathy/vasculitis) were...
The incidence of developing circulating anti-human leukocyte antigen antibodies and the kinetics T cell depletion recovery among pediatric renal transplant recipients who receive alemtuzumab induction therapy are unknown. In a collaborative endeavor to minimize maintenance immunosuppression in recipients, we enrolled 35 participants from four centers treated them with steroid-free, calcineurin-inhibitor-withdrawal regimen. At 3 months after transplant, there was greater CD4(+) than CD8(+)...
Abstract Antibody‐mediated rejection leads to allograft loss after kidney transplantation. Bortezomib has been used in adults for the reversal of antibody‐mediated rejection; however, pediatric data are limited. This retrospective study was conducted collaboration with Midwest Pediatric Nephrology Consortium. transplant recipients who received bortezomib biopsy‐proven between 2008 and 2015 were included. The objective characterize use recipients. Thirty‐three patients at nine centers. Ninety...
Prior cross-sectional studies suggest that health-related quality of life (HRQOL) worsens with more severe glomerular disease. This longitudinal analysis was conducted to assess changes in HRQOL changing disease status.Cure Glomerulonephropathy (CureGN) is a cohort patients minimal change disease, focal segmental glomerulosclerosis, membranous nephropathy, IgA vasculitis, or nephropathy. assessed at enrollment and follow-up visits 1 3 times annually for up 5 years the Patient-Reported...
Abstract We wanted to identify practice patterns and perceived barriers among pediatric nephrologists regarding STI screening reproductive health counseling in adolescent renal transplant recipients. created an online Likert‐scaled survey. Response rate was 54%. The majority (83%) believed risk their patients similar or higher than healthy teens. Interestingly, while 67% felt moderately very confident asking about sexual activity safer sex, only 43% routinely always inquired activity, 42%...
We sought to assess the prevalence of STIs, contraception use, and unintentional pregnancy in our pediatric renal transplant recipients. performed a retrospective chart review. Forty-nine 65 patients program are currently high-risk age window 13 yr or older (34 men, 15 women; mean 17 old, range 13-23 old). There was disproportionate difference sexual behavior among men women, such that while only 15% reported being sexually active, 53% women were active. Among age-group 40% on hormonal...
Abstract The negative impact of COVID‐19 on adults with underlying chronic kidney disease, including transplant recipients, has been well documented. Children have a less severe presentation and better prognosis compared to adults. However, little is known regarding the spectrum infection in children adolescents autoimmune disorders necessitating solid organ long‐term immunosuppressive therapy. Case Report. An adolescent male developed end‐stage disease secondary microscopic polyangiitis...
The 2012 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guidelines for Glomerulonephritis recommend that patients with membranous nephropathy (MN) at risk progression receive immunosuppressive therapy (IST), usually after 6 months of observation. A cyclophosphamide (CYC) or calcineurin inhibitor (CNI)-based regimen is recommended as first-line IST. However, the extent to which KDIGO recommendations are adopted in practice remains largely unknown.We evaluated prescribing...