Xuewen Xu

ORCID: 0000-0003-0567-2749
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About
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Research Areas
  • Dermatologic Treatments and Research
  • Wound Healing and Treatments
  • Reconstructive Surgery and Microvascular Techniques
  • Burn Injury Management and Outcomes
  • Reconstructive Facial Surgery Techniques
  • Vascular Malformations and Hemangiomas
  • Body Contouring and Surgery
  • Tumors and Oncological Cases
  • Facial Rejuvenation and Surgery Techniques
  • Glycosylation and Glycoproteins Research
  • Liver Disease Diagnosis and Treatment
  • Hemoglobin structure and function
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Cutaneous Melanoma Detection and Management
  • Nonmelanoma Skin Cancer Studies
  • Neurofibromatosis and Schwannoma Cases
  • Melanoma and MAPK Pathways
  • Urologic and reproductive health conditions
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Extracellular vesicles in disease
  • Neuroscience of respiration and sleep
  • Laser Applications in Dentistry and Medicine
  • Vascular Tumors and Angiosarcomas
  • Cardiac Arrest and Resuscitation
  • Liver Disease and Transplantation

West China Hospital of Sichuan University
2016-2025

Sichuan University
2016-2025

University of Nottingham Ningbo China
2025

Yueyang Hospital
2024

Shanghai University of Traditional Chinese Medicine
2024

Plastic Surgery Hospital
2023

Soil and Fertilizer Institute of Hunan Province
2022

Eastern Hepatobiliary Surgery Hospital
2021

Second Military Medical University
2021

West China Second University Hospital of Sichuan University
2021

Rationale: Over 50% of patients with heart failure have preserved ejection fraction (HFpEF), rather than reduced fraction. Complexity its pathophysiology and the lack animal models hamper development effective therapy for HFpEF. Objective: This study was designed to investigate metabolic mechanisms HFpEF test therapeutic interventions using a novel model. Methods Results: By combining age, long-term high-fat diet, desoxycorticosterone pivalate challenge in mouse model, we were able recapture...

10.1161/circresaha.120.317933 article EN Circulation Research 2020-11-12

Three-dimensional (3D) printing technology has great potential in advancing clinical medicine. Currently, the vivo application strategies for 3D-printed macroscale products are limited to surgical implantation or situ 3D at exposed trauma, both requiring exposure of site. Here, we show a digital near-infrared (NIR) photopolymerization (DNP)-based that enables noninvasive bioprinting tissue constructs. In this technology, NIR is modulated into customized pattern by micromirror device, and...

10.1126/sciadv.aba7406 article EN cc-by-nc Science Advances 2020-06-03

Per- and polyfluoroalkyl substances (PFAS) are widespread environmental contaminants associated with diseases such as cancer dyslipidemia. However, few studies have investigated the association between PFAS mixture exposure mortality in general populations.This study aimed to explore mixture, perfluorooctanoic acid (PFOA), perfluorooctane sulfonic (PFOS) U.S. adults by a nationally representative cohort.Adults ≥18 years of age who were enrolled National Health Nutrition Examination Survey...

10.1289/ehp10393 article EN public-domain Environmental Health Perspectives 2022-06-01

There is little epidemiological evidence linking the exposure of organophosphate pesticides (OPs) to liver function or injury in general population. We used data from National Health and Nutrition Examination Survey 1999-2012 investigate relationship urinary OPs with biomarkers function/liver injury.The exposures were concentrations OP metabolites (dimethyl phosphate [DMP], dimethyl thiophosphate [DMTP], diethyl [DEP] [DETP]). The health outcomes injury. multivariable linear regression...

10.1111/liv.15461 article EN Liver International 2022-10-20

Abstract Lifestyles maybe associated with the immune and inflammatory state of human body. We aimed to comprehensively explore relationship between lifestyles circulating immune-inflammatory markers in general population. Data from NHANES 1999–2014 was used. Lifestyle factors included leisure-time physical activity (LTPA), diet quality (Healthy Eating Index-2015, HEI-2015), alcohol consumption, cigarettes smoking, sleep hour sedentary time. Immune makers C-reactive protein (CRP),...

10.1038/s41598-024-63875-2 article EN cc-by Scientific Reports 2024-06-11

Keloids are benign fibrous growths that caused by excessive tissue build-up. Severe keloids exert more significant effects on patients' quality of life than do mild keloids. We aimed to identify factors associated with the progression from severe keloids, as distinct those formation keloids.In this retrospective case-control study, 251 patients diagnosed at West China Hospital between November 2018 and April 2021 were grouped according severity lesions (mild [n = 162] or 89]). collected...

10.1097/cm9.0000000000002093 article EN cc-by-nc-nd Chinese Medical Journal 2022-03-14

Ensuring the accuracy of tunnel lining inspection instruments is crucial for maintaining safety. Given complexity and variability crack morphologies widths, it particularly important to conduct more in-depth verification measurement performance existing detection instruments. To this end, our study carefully crafted standardized simulated boards using rigid plastic restored by designing specific skeleton lines. These not only lay a solid foundation theoretically calculating widths but also...

10.1049/icp.2024.2743 article EN IET conference proceedings. 2025-01-01

Abstract Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor that typically presents in infancy or early childhood. As awareness of KHE increases, it imperative the management be updated to reflect latest evidence‐based guidelines. The aim this study was integrate literature and Chinese expert opinions provide recommendations will guide diagnosis, treatment, prognosis patients with KHE. According consensus statement, 28 nationally peer‐recognized experts anomalies an medicine were...

10.1002/ijc.35344 article EN International Journal of Cancer 2025-01-20

The scarcity of knowledge regarding the epidemiology and temporal patterns viral skin diseases worldwide poses significant challenges to their control management. We analyzed global incidence, prevalence, age-standardized rates (ASR) disability-adjusted life years (DALYs) for in 2021. To examine trends from 1990 2021, we employed EPAC model, assessing changes by country, gender, age, Socio-demographic Index (SDI), GBD regions. Additionally, utilized age-period-cohort (APC) model Bayesian...

10.3389/fpubh.2025.1464372 article EN cc-by Frontiers in Public Health 2025-02-19

Submental fat (SMF) is a common aesthetic concern traditionally treated with liposuction. Non-surgical alternatives like injectable deoxycholic acid are gaining popularity. However, no related products have been clinically approved in China. This study evaluated the efficacy and safety of MEI005, acid-based formulation, reducing SMF Chinese adults. multicenter, randomized, double-blind, placebo-controlled phase III trial included 325 adults moderate to SMF. Participants received MEI005 or...

10.1093/asj/sjaf031 article EN cc-by Aesthetic Surgery Journal 2025-03-04

The data that support the findings of this study are openly available in GBD Study 2021 at https://vizhub.healthdata.org/gbd-results/.

10.1111/cea.70037 article EN Clinical & Experimental Allergy 2025-03-18

Few studies have explored the impact of perchlorate, nitrate, and thiocyanate (PNT) on kidney function. This study aimed to evaluate association urinary levels PNT with renal function as well prevalence chronic disease (CKD) among general population in United States.This analysis included data from 13,373 adults (≥20 years) National Health Nutrition Examination Survey 2005 2016. We used multivariable linear logistic regression, explore associations Restricted cubic splines were assess...

10.1097/cm9.0000000000002586 article EN cc-by-nc-nd Chinese Medical Journal 2023-04-26

(1) Background: Prolonged coexposure to environmental contaminants is reportedly associated with adverse impacts on skin health. However, the collective effects of contaminant mixtures psoriasis prevalence remain unclear. (2) Methods: A nationally representative cohort study was conducted using data from National Health and Nutrition Examination Survey 2003–2006 2009–2014. The association between exposures analyzed through weighted quantile sum regressions, restricted cubic splines,...

10.3390/toxics12070522 article EN cc-by Toxics 2024-07-19
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