A5080493382- Vitamin C and Antioxidants Research
- Gastric Cancer Management and Outcomes
- Retinoids in leukemia and cellular processes
- Cancer and Skin Lesions
- Testicular diseases and treatments
- Liver Disease Diagnosis and Treatment
- Nonmelanoma Skin Cancer Studies
- Plant Stress Responses and Tolerance
- Colorectal Cancer Screening and Detection
- Ear and Head Tumors
- Health and Wellbeing Research
- Helicobacter pylori-related gastroenterology studies
- Autoimmune Bullous Skin Diseases
- Cancer Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
- Hernia repair and management
- Eosinophilic Esophagitis
- Colorectal and Anal Carcinomas
- Sarcoma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Tumors and Oncological Cases
- Influenza Virus Research Studies
- Hepatitis B Virus Studies
- Cancer Cells and Metastasis
- Infectious Encephalopathies and Encephalitis
National Health Insurance Service
2023
National Health Insurance Service Ilsan Hospital
2023
Yonsei University
2001-2019
Samsung Medical Center
2011-2019
Sungkyunkwan University
2011-2019
Gangnam Severance Hospital
2018-2019
Gachon University Gil Medical Center
2004-2012
Chung-Ang University
2012
Deleted Institution
1996-2010
Pain and Rehabilitation Medicine
2009
Xyloglucan endotransglucosylase/hydrolase (XTH) has been recognized as a cell wall‐modifying enzyme, participating in the diverse physiological roles. From water‐stressed hot pepper plants, we isolated three different cDNA clones (pCaXTH1, pCaXTH2, and pCaXTH3) that encode XTH homologs. RT‐PCR analysis showed CaXTH mRNAs were concomitantly induced by broad spectrum of abiotic stresses, including drought, high salinity cold temperature, response to stress hormone ethylene, suggesting their...
OBJECTIVES: We assessed the association among ultrasonographically detected non-alcoholic fatty liver disease (US-NAFLD), metabolic syndrome (MetS), and insulin resistance (IR) in non-obese, non-diabetic middle-aged adults, to find out whether US-NAFLD is independently associated with IR this population. METHODS: A total of 5,878 non-obese (body mass index, ≥18.5 <25), individuals were analyzed. was estimated homeostasis model assessment index (HOMA2–IR) defined when HOMA2–IR ≥1.5. MetS by...
An auxiliary factor of mammalian multi-aminoacyl-tRNA synthetases, p43, is thought to be a precursor endothelial monocyte-activating polypeptide II (EMAP II) that triggers proinflammation in leukocytes and macrophages. In the present work, however, we have shown p43 itself specifically secreted from intact cells, while EMAP released only when cells are disrupted. Secretion was also observed its expression increased. These results suggest should real cytokine by an active mechanism. To...
Epidemiologic and clinical data suggest that Helicobacter pylori infection is a contributing factor in the progression of atherosclerosis. However, specific cardiovascular disease risk factors associated with H. remain unclear. We performed cross-sectional study 37,263 consecutive healthy subjects who underwent routine health check-up. In multivariable log Poisson regression models adjusted for potential confounders, associations seropositivity higher LDL-C (relative [RR], 1.21; 95%...
The purpose of our study was to evaluate the MRI features tailgut cysts in five patients.Our results suggest that may be useful diagnosis cyst. A multilocular cystic mass presacral space is a characteristic finding cyst, which also revealed as consisting large cyst accompanied by small peripheral However, further studies are necessary establish usefulness for evaluating cysts.
Phosphoinositide‐specific phospholipase C (PI‐PLC) catalyzes the hydrolysis of phosphatidylinositol 4,5‐bisphosphate to generate inositol 1,4,5‐trisphosphate and diacylglycerol, both which act as secondary messengers in animal cells. In this report, we identified Vigna radiata L. (mung bean) three distinct partial cDNAs (pVr‐PLC1, pVr‐PLC2, pVr‐PLC3), encode forms putative PI‐PLC. All Vr‐PLC genes were transcriptionally active displayed unique patterns expression. The Vr‐PLC1 Vr‐PLC2...
The purpose of our study was to describe acute necrotizing encephalopathy in Korean infants and children, we sought evaluate the prognostic factors.Acute diagnosed 14 children. We retrospectively analyzed neuroimaging findings including follow-up changes. clinical course disease graded, evaluated factors age, serum level aminotransferase, hemorrhage, localized atrophy brain.This predominantly affected bilateral thalami (n = 14), pons 12), midbrain 10) a symmetrical pattern. Hemorrhage...
Although caudal block via the sacral hiatus is a common regional technique in children, it sometimes difficult to identify hiatus. A needle approach S2-3 interspace can be used as an alternative conventional approach. The authors compared feasibility and clinical characteristics between hiatal approach, addition ultrasound study.Sacral space depth, dural sac end level, depth were evaluated using with high-frequency linear probe lateral decubitus position 317 anesthetized children (study 1)....
Vitamin C plays a crucial role in the suppression of proliferation several types cancer. Over-expression cyclooxygenase (COX)-2 and type I insulin-like growth factor (IGF) receptor are important for protection from apoptosis malignancies. However, its specific mechanisms, especially interaction between COX-2 expression IGF-I axis mediated by vitamin C, remain yet to be clarified. Therefore, we investigated effects on melanoma cells via modulation axis. As result, found that 1.0 mM inhibits...
Abstract Background/Aims Serum alanine aminotransferase ( ALT ) is an easily available, low‐cost screening tool for detecting silent chronic liver disease. Recent studies have suggested that the currently accepted healthy thresholds be lowered. Methods In this retrospective cross‐sectional study, we determined upper values in a nationally representative cohort n = 3337) from Fourth Korea National Health and Nutrition Examination Survey KNHANES IV ). Sensitivity specificity of used threshold...
Objectives The purpose of this study was to compare the size, shape, echogenicity, and blood flow appendix testis on sonography in control subjects patients with a torsed evaluate usefulness as well limitations these criteria. Methods This retrospective analysis 11 lesions testes 15 normal 12 children. following gray scale color Doppler sonographic features were analyzed: testis. Results size larger than (P < .05). A spherical shape more common There no within both testes. However, frequency...
Abstract Vitamin C has inconsistent effects on malignant tumor cells, which vary from growth stimulation to apoptosis induction. It is well known that melanoma cells are more susceptible vitamin than any other but the precise mechanism remains be elucidated. In present study, proliferation of B16F10 was suppressed by C, induced arrest in a dose‐dependent manner without cytotoxic effects. Therefore, we investigated changes cell cycle distribution staining DNAs with propidium iodide (PI). The...
The association between obesity and peptic ulcer disease (PUD) is inconclusive. To evaluate the of metabolically healthy (MHO) with PUD risk, we performed a retrospective cohort study 32,472 subjects without at baseline who underwent repeated health examinations. Participants were stratified by body mass index (BMI) state. Hazard ratios (HRs) 95% confidence intervals (CIs) calculated using Cox proportional hazard modelling. During follow-up period, 1940 cases occurred. PUD, particularly...
It has been reported that vitamin C plays an effective role in the treatment and prevention of cancer, but its specific mechanisms are still largely unknown. The incidence colon cancer is now increasing Korea. Therefore, we have examined here effect on induction apoptosis related mechanisms. We found remarkable increase calcium influx endoplasmic reticulum (ER) human cell line, HCT-8. However, C-induced was effectively inhibited by pre-treatment BAPTA-AM (1,2-bis(o-aminophenoxy)...
The objective of this study was to establish modified cutoff values serum alpha-fetoprotein (AFP) according hepatitis status. While AFP is used as a marker in the diagnosis or monitoring hepatocellular carcinoma (HCC), its use screening method general population controversial. We evaluated performance prevalent East Asian population, and suggest different individual's test 48,123 consecutive Koreans during period from March, 2012 August, 2013 who underwent routine health checks at single...
Little is known about the risk factors associated with serrated polyps, because early studies, which occurred before new World Health Organization classification was introduced, included mixtures of polyps. This study aimed to evaluate presence sessile adenomas (SSAs) and traditional (TSAs) using big data analytics.Using a case-control design, we evaluated SSAs TSAs. Subjects who underwent colonoscopies from 2002 2012 as part comprehensive health screening programs undertaken at Samsung...
Imaging Findings of Hepatic Sinusoidal DilatationDal Mo Yang1, Dong Hae Jung2, Chul Hi Park1, Jee Eun Kim1 and Soo Jin Choi1Audio Available | Share
Purpose Melanoma is a highly heterogeneous neoplasm, composed of subpopulations tumor cells with distinct molecular and biological phenotypes genotypes. In this study, to determine the genetic heterogeneity between primary metastatic melanoma in Korean patients, we evaluated several well-known alterations melanoma. addition, elucidate clinical relevance each alteration lesions, features patient outcome were collected. Materials Methods addition data, BRAF, NRAS, GNAQ/11 mutation KIT...
Patients with chronic lymphocytic leukemia (CLL) rarely exhibit an exaggerated insect bite-like reaction without a history of arthropod bite. We report case in 74-year old man CLL. The patient presented 2-year recurrent itchy erythematous patches and blisters on the whole body. He had been diagnosed CLL 2 years ago, skin lesions developed 1 month after remission. result biopsy was consistent Immunohistochemical staining infiltrated cells showed positive reactions for CD3, CD5 negative CD20,...