A5042232861- Geomagnetism and Paleomagnetism Studies
- Magnetic and Electromagnetic Effects
- Geology and Paleoclimatology Research
- Gut microbiota and health
- Bacteriophages and microbial interactions
- Muscle Physiology and Disorders
- Liver physiology and pathology
- Aquaculture disease management and microbiota
- Education and Work Dynamics
- Mycotoxins in Agriculture and Food
- Cardiovascular Health and Risk Factors
- Innovative Educational Techniques
- Higher Education and Teaching Methods
- Cancer, Hypoxia, and Metabolism
- Electric Power Systems and Control
- Genetics, Aging, and Longevity in Model Organisms
- Geochemistry and Elemental Analysis
- Liver Disease Diagnosis and Treatment
- Plant Reproductive Biology
- Agricultural pest management studies
- Insect Resistance and Genetics
- Insect and Pesticide Research
- Plant Ecology and Soil Science
- Organ Transplantation Techniques and Outcomes
- Genomics and Phylogenetic Studies
Baotou Teachers College
2019-2024
Guangxi Medical University
2024
China Agricultural University
2014-2019
Beijing Institute of Geology for Mineral Resources
2017
Fu Associates (United States)
2001
Iowa State University
1997
The gl8 locus of maize (Zea mays L.) was previously defined by a mutation that reduces the amount and alters composition seedling cuticular waxes. Sixty independently derived mutant alleles were isolated from stocks carried Mutator transposon system. A DNA fragment contains Mu8 co-segregates with one these alleles, gl8-Mu3142, identified cloned. flanking shown via allelic cross-referencing experiments to represent locus. probe revealed 1.4-kb transcript present in wild-type leaves and,...
Introduction MSTN is a well-studied inhibitor of skeletal muscle development, but its mechanism affecting gut metabolites and the functions it exerts through this pathway are still unclear. This study aims to reveal how affects metabolism process by regulating metabolites. Methods Combined analysis jejunal contents metabolome tissue transcriptome was used compare differences in intestinal gene expression between mutant wild-type bovines. Results Metabolomic identified that compared bovine,...
We report the complete genomic sequence of Magnetospirillum gryphiswaldense MSR-1 (DSM 6361), a type strain genus belonging to Alphaproteobacteria. Compared reported draft sequence, extensive rearrangements and differences were found, indicating high flexibility "domestication" by accelerated evolution upon repeated passaging.
Magnetosome synthesis ability of Magnetospirillum gryphiswaldense MSR-1 in an autofermentor can be precisely controlled through strict control dissolved oxygen concentration. In this study, using transcriptome data we discovered gene transcriptional differences and compared physiological characteristics cells cultured under aerobic (high-oxygen) micro-aerobic (low-oxygen) conditions. The results showed that 77 genes were up-regulated 95 down-regulated significantly situation. These involved...
Myostatin ( MSTN ) negatively regulates muscle development and positively metabolism through various pathways. Although function in cattle has been widely studied, the changes gut microbiota due to mutation, which contribute host health by regulating its metabolism, remain unclear. Here, high-throughput sequencing of 16S rRNA gene was conducted analyze wild-type (WT) mutant (MT) cattle. A total 925 operational taxonomic units (OTUs) were obtained, classified into 11 phyla 168 genera. Alpha...
Myostatin ( MSTN ) regulates muscle development and body metabolism through a variety of pathways is core target gene for editing in livestock. Gut fungi constitute small part the gut microbiome are important to host health metabolism. The influence mutations on bovine remains unknown. In this study, Internal Transcribed Spacer (ITS) high-throughput sequencing was conducted explore composition mutant (MT) wild-type (WT) cattle, 5,861 operational taxonomic units (OTUs) were detected...
Introduction Actinobacillus pleuropneumoniae , the causative agent of porcine pleuropneumonia, poses a significant threat to global swine populations due its high prevalence, mortality rates, and substantial economic ramifications. Understanding pathogen's defense mechanisms against host-produced reactive oxygen species is crucial for survival, with OxyR, conserved bacterial transcription factor, being pivotal in oxidative stress response. Methods This study investigated presence role OxyR...
Background and Aims: Hepatic ischemia-reperfusion injury (IRI) is unavoidable even despite the development of more effective surgical approaches. During hepatic IRI, activated HSC (aHSC) are involved in liver recovery. Approach Result: A proportion aHSC increased significantly both mouse tissues with IRI primary HSCs LX-2 cells during hypoxia-reoxygenation. “Loss-of-function” experiments revealed that depleting gliotoxin exacerbated damage mice. Subsequently, we found transcription mRNA...
Magnetotactic bacteria (MTB) are specialized microorganisms that synthesize intracellular magnetite particles called magnetosomes. Although many studies have focused on the mechanism of magnetosome synthesis, it remains unclear how these structures formed. Recent reports suggested formation is energy dependent. To investigate relationship between and metabolism, a global regulator, named Crp, which mainly controls carbon metabolism in most microorganisms, was genetically disrupted...
Abstract Background Natural biological magnetite nanoparticles are widely distributed from microorganisms to humans. It is found be very important in organisms, especially navigation. Moreover, purified also have potential applications bioengineering and biomedicine. Magnetotactic bacteria (MTB) considered one of the most abundant species around world which can form intracellular membrane enveloped magnetic nanoparticles, referred as magnetosomes. To our knowledge, biomineralization...
Carpel morphogenesis is crucial for seed development, and fruit size quality, carpel number one measure of the level plant evolution. A comparative study gene modulation was initiated to ontogeny bi- tricarpellate fruits. In our study, ‘Xiangfei’ grapevine (Vitis vinifera) used as material because its high occurrence. Results showed that congenital fusion main pathway ovary ontogeny. There were three ventral sutures on fruits in period flowering, this feature absent from bicarpellate From 20...
Magnetotactic bacteria (MTB) synthesize intracellular membrane-enveloped magnetite bodies known as magnetosomes which have been applied in biotechnology and medicine. A series of proteins involved ferric ion transport redox required for formation identified but the knowledge magnetosome biomineralization remains very limited. Here, we identify a novel OxyR homolog (named OxyR-Like), disruption resulted low ferromagnetism disfigured nano-sized iron oxide crystals. High resolution-transmission...
The formation of magnetosomes inside magnetotactic bacteria is a complex process strictly controlled by the intracellular metabolic regulatory system. A series transcriptional regulators are involved in biosynthesis magnetosome, including OxyR-Like protein, which indispensable for maturation Magnetospirillum Gryphiswaldense MSR-1. In this study, new function protein that helps cells resist reactive oxygen species (ROS) was identified. comparison expression profile data between wild-type...
Bacillus cereus is a common foodborne pathogen. Accidently eating food contaminated by B. will cause vomiting or diarrhea, and even death in severe cases. In the present study, strain was isolated from spoiled rice streak culture. The pathogenicity drug resistance of were analyzed sensitivity test PCR amplification virulence-associated gene respectively. Cultures purified injected intraperitoneally into mice to examine their effects on intestinal immunity-associated factors gut microbial...
Deoxynivalenol (DON) is a mycotoxin commonly found in cereals. It has strong toxicity with high stability, thus it easy to remain food and cause serious poisoning symptoms consumers. To establish an efficient simple DON detection system, biological nano magnetic particle called bacterial magnetosomes (BMs) extracted from magnetotactic bacteria ultrasonic crushing adsorption was used this study. A single-stranded DNA aptamer specifically binding coupled the surface of MBs by two different...
Abstract Magnetosome formation inside magnetotactic bacteria is a complex process strictly regulated by intracellular metabolic regulation system. A series of transcriptional regulators have been proved involved in magnetosome bio-synthesis, including OxyR-Like, which indispensable during maturation Magnetospirillum gryphiswaldense MSR-1. In this study, new function OxyR-Like was identified that it helps cell to defense reactive oxygen species (ROS). Comparison expression profile data...