A5053653312- Neuroinflammation and Neurodegeneration Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Intensive Care Unit Cognitive Disorders
- Estrogen and related hormone effects
- Menopause: Health Impacts and Treatments
- Mechanisms of cancer metastasis
- Nanowire Synthesis and Applications
- Ferroptosis and cancer prognosis
- Cerebrovascular and Carotid Artery Diseases
- Perovskite Materials and Applications
- Anesthesia and Neurotoxicity Research
- Conducting polymers and applications
- Graphene research and applications
- S100 Proteins and Annexins
- Silicon Nanostructures and Photoluminescence
- Nuclear Receptors and Signaling
- Cancer Mechanisms and Therapy
- Acute Ischemic Stroke Management
- Quantum Dots Synthesis And Properties
- Neurological Disease Mechanisms and Treatments
- Neuroscience and Neuropharmacology Research
- Aortic aneurysm repair treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Semiconductor materials and interfaces
- GDF15 and Related Biomarkers
Chinese PLA General Hospital
1991-2025
People's Liberation Army No. 150 Hospital
2024
Chinese People's Liberation Army
2024
Creative Commons
2024
Henan University
2024
Ningxia University
2022-2023
Changshu Institute of Technology
2015-2021
First Affiliated Hospital of Chinese PLA General Hospital
2020
Air Force Medical University
2013-2017
Xijing Hospital
2013-2017
Hybrid organic–inorganic perovskites have attracted intensive interest as light absorbing materials in solid‐state solar cells. Herein, we demonstrate a high‐performance CH 3 NH PbI ‐based perovskite photodetector constructed on the flexible indium tin oxide (ITO) coated substrate even after 200 bending cycles. The as‐fabricated devices show high responsivity, broad spectrum response from ultraviolet to whole visible light, long‐term stability, and on‐off ratio. Particularly, atomic layer...
The steroid hormone estrogen (17-β-estradiol, E2) provides neuroprotection against cerebral ischemic injury by activating receptors. novel receptor G protein-coupled 30 (GPR30) is highly expressed in the brain and acute stroke. However, underlying mechanisms remain unclear.In this study, ovariectomized female mice were subjected to middle artery occlusion (MCAO), E2, G1, ICI182780 administered immediately upon reperfusion. infarction volume, neurological scores, neuronal injuries examined....
Abstract Background Ischemic stroke is the second leading cause of death globally. The narrow time window for administering effective thrombolytic therapy motivates search alternative prevention strategies. Microglia and astrocyte activation-mediated inflammation play a pivotal role in ischemic injury. Cottonseed oil (CSO) has been shown to exert anti-inflammatory effects against peripheral tissue injury, although CSO mostly used as solvent lipid-soluble drugs. However, neuroprotection not...
<b>Clinical question</b> <b>Can ginger treat nausea and vomiting of pregnancy?</b> <b>Bottom line</b> <b>In the first trimester might improve by about 4 points on a 40-point scale or stop for 1 in 3 women at 6 days. The largest study suggests no increase fetal malformations stillbirths, but smaller studies suggest otherwise.</b>
Astrocytes possess different morphological characteristics depending on the cerebral region in which they are found. However, none of current astrocytic markers can label all subpopulations successfully. Thus, identifying appropriate marker for a specific scientific investigation is critical. Here, we compared distribution and protein expression three astrocyte markers: NDRG2, GFAP, S100 β , cortex, hippocampus, thalamus. NDRG2- -positive astrocytes were distributed more uniformly than...
Ultrathin 10 nm ALD TiO<sub>2</sub> films as efficient electron transport layers for perovskite planar solar cells with an efficiency of 13.6%.
Abstract Perovskites have attracted intensive attention as promising materials for the application in various optoelectronic devices due to their large light absorption coefficient, high carrier mobility, and long charge diffusion length. However, performance of pure perovskite nanocrystals‐based device is extremely restricted by limited transport capability existence a number grain boundary between nanocrystals. To address these issues, high‐performance photodetector based on all‐inorganic...
This study aimed to investigate the clinical prognostic values of preoperative systemic-immune-inflammation index (SII) in older patients undergoing non-cardiac surgery, using perioperative ischemic stroke as primary outcome.This retrospective cohort included who underwent surgery between January 2008 and August 2019. The were divided into SII < 583 ≥ group according optimal cut-off value. outcome interest was within 30 days after surgery. Primary, sensitivity, subgroup analyses performed...
CNS inflammation is known to be an important pathogenetic mechanism of perioperative neurocognitive disorder (PND), and iron overload was reported participate in this process accompanied by oxidative stress. Ferroptosis iron-dependent form cell death, occurs multiple neurodegenerative diseases with cognitive disorder. However, the effect ferroptosis inflammation-related PND unknown. In study, we found that inhibitor liproxstatin-1 ameliorated memory deficits mouse model lipopolysaccharide...
Abstract Aims To compare the performance of logistic regression and machine learning methods in predicting postoperative delirium (POD) elderly patients. Method This was a retrospective study perioperative medical data from patients undergoing non‐cardiac non‐neurology surgery over 65 years old January 2014 to August 2019. Forty‐six variables were used predict POD. A traditional five models (Random Forest, GBM, AdaBoost, XGBoost, stacking ensemble model) compared by area under receiver...
Abstract Background Postoperative delirium (POD) is more prevalent among elderly patients with type 2 diabetes mellitus (T2DM). Insulin resistance (IR) can be assessed using the triglyceride-glucose (TyG) index, a novel biomarker. This study aims to investigate predictive potential of TyG index for POD in T2DM. Materials and methods Elderly (≥ 65) T2DM who underwent non-neurosurgery non-cardiac surgery were enrolled. Univariate multivariate logistic regression analyses conducted assess...
Abstract Background Postoperative cognitive impairment are common neural complications in older surgical patients and exacerbate the burden of medical care on families society. Methods A total 140 who were scheduled for elective orthopaedic surgery or pancreatic with general anaesthesia randomly assigned to Group S I a 1:1 allocation. Patients received intranasal administration 400 μL normal saline 40 IU/400 insulin, respectively, once daily from 5 minutes before induction until 3 days...
Abstract The incidence of ischemic stroke is significantly increased in postmenopausal women. However, the neuroprotective effects estrogen replacement therapy (ERT) against remain controversial and role astrocytes ERT has rarely been explored. In this study, we investigated selective receptor (ER) agonists on activation neuronal apoptosis mice under conditions cell culture oxygen glucose deprivation reperfusion (OGD-R) global cerebral ischemia (GCI). We demonstrated that hippocampal...
Abstract JOURNAL/nrgr/04.03/01300535-202403000-00040/inline-graphic1/v/2023-09-27T141015Z/r/image-tiff β-Sitosterol is a type of phytosterol that occurs naturally in plants. Previous studies have shown it has anti-oxidant, anti-hyperlipidemic, anti-inflammatory, immunomodulatory, and anti-tumor effects, but unknown whether β-sitosterol treatment reduces the effects ischemic stroke. Here we found that, mouse model stroke induced by middle cerebral artery occlusion, reduced volume infarction...
Dexmedetomidine (DEX) is widely used for adjuvant sedation and analgesia in gastrointestinal surgeries. The authors aimed to reassess the effects of intraoperative DEX on acute pain by comprehensive analysis multiple dimensions pain.In this multicentre cohort study, patients undergoing surgeries were prospectively enrolled China Acute Postoperative Pain Study. Patients divided into non-DEX groups based whether was during surgery. Patient satisfaction with treatment (rated a numeric rating...
In this study, metal composite oxides grown on nickel foam were prepared, which modified by dopamine and biochar to obtain cauliflower-shaped Co2MnO4/[email protected]/BC adsorption material adsorb cationic dyes from aqueous solutions. The maximum amounts qmax for methylene blue (MB), malachite green (MG), crystal violet (CV) 8.44, 41.03 3.39 mg g−1, the aligned with Langmuir isothermal model as single molecular layer a homogeneous surface. experiments of conducted using lake water in...
Abstract Background The prognostic nutritional index (PNI) is a indicator and predictor of various diseases. However it unclear whether PNI can be perioperative ischemic stroke. This study aims to evaluate the association preoperative stroke in patients undergoing non-cardiac surgery. Methods retrospective cohort included who underwent noncardiac surgery between January 2008 August 2019. were divided into ≥ 38.8 < groups according cut-off value PNI. Univariate multivariate logistic...
Abstract Background Because neuroprotective effects of estrogen remain controversial, we aimed to investigate the effect different doses estradiol (E2) on cerebral ischemia using both in vivo and vitro experiments. Results PC12 cells were cultured at physiological (10 nM 20 nM) or pharmacological μM μM) dosages E2 for 24 hours (h). The results 5-bromodeoxyuridine (Brdu) incorporation flow cytometric analysis showed that enhanced cell proliferation inhibited proliferation. After exposed...