A5100349294- Crystallization and Solubility Studies
- Crystallography and molecular interactions
- Immune Cell Function and Interaction
- Drug Solubulity and Delivery Systems
- T-cell and B-cell Immunology
- Chromatography in Natural Products
- Inflammasome and immune disorders
- Ionic liquids properties and applications
- Oxidative Organic Chemistry Reactions
- Power Systems and Renewable Energy
- Advanced Drug Delivery Systems
- Gout, Hyperuricemia, Uric Acid
- Plant Molecular Biology Research
- Surfactants and Colloidal Systems
- Analytical Chemistry and Chromatography
- Ubiquitin and proteasome pathways
- Multicomponent Synthesis of Heterocycles
- Cancer Immunotherapy and Biomarkers
- Mast cells and histamine
- Immunotherapy and Immune Responses
- Advanced Measurement and Detection Methods
- Chemical Synthesis and Reactions
- Advanced biosensing and bioanalysis techniques
- Pharmacological Effects of Natural Compounds
- Protein Tyrosine Phosphatases
Beijing University of Chinese Medicine
2022-2025
Yangzhou University
2025
Hebei University
2023-2024
China Electronics Technology Group Corporation
2024
Jilin Medical University
2022-2023
Changchun University of Chinese Medicine
2020-2023
National Engineering Research Center for Wheat
2023
Henan Agricultural University
2022-2023
Tibetan Traditional Medical College
2019-2023
Tianjin University
2023
In diabetic patients complicated with colorectal cancer (CRC), metformin treatment was reported to have diverse correlation CRC-specific mortality. laboratory studies, affect the survival of stem cells (CSCs) in breast and pancreatic cancers glioblastoma. Although cscs play a critical role resistance 5-fluorouracil (5-FU) chemotherapy CRC patients, effect on synergistic combination 5-FU are not reported. present study pathological examinations were performed 86 type 2 DM who had been divided...
Background:Lamiophlomis rotata (LR) showed favorable clinical effect and safety on rheumatoid arthritis (RA), but its active ingredients mechanisms against RA remain unknown. The aim of this work was to explore the LR by network pharmacology. Methods: Compounds from were identified using literature retrieval screened absorption, distribution, metabolism, excretion, toxicity (ADMET) evaluation. Genes related selected compounds or public databases, overlapping genes between target Venn...
In diabetic islets, the infiltration of macrophages into intra-islets triggers islet β cells dysfunction. Lycopene may preserve M1/M2 macrophage homeostasis to improve function via TLR4/MyD88/NF-κB signaling pathway.
Abstract Wheat is one of the world’s major staple food crops, and breeding for improvement grain yield a priority under scenarios climate change population growth. WRKY transcription factors are multifaceted regulators in plant growth, development, responses to environmental stimuli. In this study, we identify gene TaGSNE (Grain Size Number Enhancer) common wheat, find that it has relatively high expression leaves roots, induced by multiple abiotic stresses. Eleven single-nucleotide...
Cytokines mediate the interaction of immune cells. Discovery novel potential cytokines is great value for both basic research and clinical application. In this study, we identified a immune-related molecule, transmembrane protein 98 (TMEM98), through high-throughput screening platform at genome-wide level using strategy immunogenomics. So far, there no characteristic functional report about it. demonstrate that TMEM98 exists as type II in ectopically endogenously expressed systems....
Small extracellular vesicles (sEVs) play important roles in mediating intercellular communication and regulating biological processes. Facile sEV isolation is the essential preliminary issue for their function investigation downstream biomedical applications, while traditional methods are challenged by tedious procedures, low purity, yield, potential damage. In this work, we developed an paper-based device (sEV-IsoPD) based on a three-dimensional (3D) paper chip, which composed of porous...
A green one-pot synthetic strategy was proposed to design a water-compatible surface molecularly imprinted composite with specific selectivity and high adsorption capability for selective extraction of chlorogenic acid from aqueous systems.
The direct ketohydroxylation of a variety 1-aryl-1-alkenes with H2O2, catalyzed by the inexpensive 12-tungstophosphoric acid/cetylpyridinium chloride system under very mild conditions, was achieved. Various acyloins were obtained in good yields and high regioselectivies.
Identification of novel stimulatory cytokines with antitumor function would have great value in tumor immunotherapy investigations. Here, we report LYG1 (Lysozyme G-like 1) identified through the strategy Immunogenomics as a classical secretory protein tumor-inhibiting function. recombinant (rhLYG1) could significantly suppress growth B16 tumors WT B6 mice, but not SCID-beige Rag1−/− CD4+- or CD8+ T cell-deleted mice. It increase number CD4+ and cells tumor-infiltrating lymphocytes,...