A5100384867- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Pleural and Pulmonary Diseases
- Myasthenia Gravis and Thymoma
- Tracheal and airway disorders
- Radiomics and Machine Learning in Medical Imaging
- Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Medical Imaging and Pathology Studies
- Metastasis and carcinoma case studies
- Gastric Cancer Management and Outcomes
- Congenital Diaphragmatic Hernia Studies
- Pituitary Gland Disorders and Treatments
- Thyroid and Parathyroid Surgery
- Salivary Gland Tumors Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Head and Neck Cancer Studies
- Acute Lymphoblastic Leukemia research
- Cancer Genomics and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Meningioma and schwannoma management
- Hepatocellular Carcinoma Treatment and Prognosis
- Sympathectomy and Hyperhidrosis Treatments
- Peripheral Neuropathies and Disorders
- Ophthalmology and Eye Disorders
First Affiliated Hospital of Bengbu Medical College
2024-2025
Peking University People's Hospital
2015-2024
Peking University
2015-2024
XinHua Hospital
2024
Shanghai Jiao Tong University
2023-2024
Chengdu Second People's Hospital
2024
Zhejiang University
2024
Nanjing Medical University
2020-2023
Jiangsu Province Hospital
2020-2023
Chinese PLA General Hospital
2020-2023
Abstract EMERGING-CTONG 1103 showed improved progression-free survival (PFS) with neoadjuvant erlotinib vs. chemotherapy for patients harbouring EGFR sensibility mutations and R0 resected stage IIIA-N2 non-small cell lung cancer (NSCLC) (NCT01407822). Herein, we report the final results. Recruited were randomly allocated 1:1 to group (150 mg/day orally; phase 42 days adjuvant 12 months) or GC (gemcitabine 1250 mg/m 2 plus cisplatin 75 intravenously; cycles in phase). Objective response rate...
Abstract Circulating tumor DNA (ctDNA) isolated from peripheral blood has recently been shown to be an alternative source detect gene mutations in primary tumors; however, most previous studies have focused on advanced stage cancers and few evaluated ctDNA detection early-stage lung cancer. In the present study, samples were collected prospectively 58 non-small cancer (NSCLC) patients (stages IA, IB IIA) a targeted sequencing approach was used somatic driver matched (tDNA) plasma ctDNA. We...
Abstract Epidural analgesia is regarded as the gold method for controlling post‐thoracotomy pain. Intercostal nerve cryoanalgesia can also produce satisfactory analgesic effects, but suspected to increase incidence of chronic However, randomized controlled trials comparing these two methods acute pain effects and incidents have not been conducted previously. We studied 107 adult patients, allocated randomly thoracic epidural bupivacaine morphine or intercostal cryoanalgesia. Acute scores...
9005 Background: ADJUVANT-CTONG1104, a randomized phase 3 trial showed adjuvant gefitinib treatment significantly improved disease-free survival (DFS) vs standard doublet chemotherapy in patients (pts) with epidermal growth factor receptor ( EGFR) mutation-positive resected stage II-IIIA (N1-N2) non-small-cell lung cancer (NSCLC). 5-year rate of N1N2 were 38%-50% IASLC staging system. Here, we present the final overall (OS) results from study. Methods: From Sep 2011 to April 2014, 222...
Pulmonary complications (PCs) may influence long-term survivor. We sought to determine the impacts of major pulmonary (MPCs) and identify independent risk factors in non-small cell lung cancer (NSCLC) patients.A retrospective study was conducted analyze PCs 828 NSCLC patients who underwent video-assisted thoracic surgery (VATS) lobectomy Peking University Hospital, were graded according TMM classification. The effects on prognosis analyzed by using Kaplan-Meier method. Multivariate logistic...
Video-assisted thoracoscopic surgery (VATS) lobectomy is a newly developed type of for lung cancer and has been demonstrated obvious minimally-invasive advantages compared with traditional thoracotomy. Theoretically, that less trauma leads to quicker recovery may facilitate administration adjuvant chemotherapy. We tested this hypothesis in study.One hundred ten NSCLC patients underwent chemotherapy from June 2004 2010 was analyzed. The baseline characteristic criteria, variables related...
Chylothorax is an infrequent but relatively serious complication after lung cancer surgery. Finding the leakage site and identifying thoracic duct (TD) are key points of surgical intervention for chylothorax. In this study, first time, we demonstrated near-infrared fluorescence imaging with indocyanine green (ICG) in video-assisted thoracoscopic surgery (VATS) chylothorax humans. This study included 4 patients diagnosed who underwent VATS intervention; 0.2 mg/kg ICG was injected...
The adjuvant treatment of patients with resected lung adenocarcinoma (LUAD) remains unstandardized. We analyzed the survival outcomes these based on EGFR mutation status and chemotherapy treatment. This noninterventional real-world study (ICAN) enrolled Chinese stages I to III LUAD from April 8, 2010, December 31, 2010. Tumor 3-year disease-free (DFS) were determined. extension phase provided long-term follow-up overall (OS) as primary end point. Secondary points included DFS prognostic...
The prevalence of aortic valve stenosis is on the rise, primarily due to an aging population. Transcatheter Aortic Valve Replacement (TAVR) has emerged as effective treatment option, especially for patients at high surgical risk. However, variation in post-TAVR quality life across patient groups warrants further examination understand contributing factors. This study aims evaluate post-TAVR, characterize distinct group profiles, and identify key factors that influence their life. From July...
The triglyceride-glucose (TyG) index, a biomarker commonly used to evaluate metabolic health status, can predict unfavorable outcomes. Thus, we aimed explore evidence regarding the prognostic value of TyG index in patients with ischemic cardiomyopathy and heart failure preserved ejection fraction (HFpEF). We enrolled 277 consecutive participants new-onset HFpEF who underwent coronary artery bypass grafting (CABG). primary study endpoint was major adverse cardiovascular events (MACEs),...
Abstract Background The purpose of this study was to compare the efficacy and safety two preoperative pulmonary nodule localization techniques using microcoil hookwire. Methods A total 307 patients with 324 nodules were included in from March 2012 October 2016 medical centers. Baseline data, positioning operation success rate, complications, surgery pathological results statistically analyzed. Complications used as dependent variables, whereas others covariates for propensity score matching...
The optimal surgical strategy for early-stage non-small cell lung cancer (NSCLC) with visceral pleural invasion (VPI) remains unclear. Due to limited prospective comparative data these modalities, the objective of current study was compare long-term survival outcomes sublobectomy (Sub) versus lobectomy (Lob) NSCLC a tumor size ≤2 cm and VPI.Patients characterized by VPI diagnosed between 2004 2013 were identified from Surveillance, Epidemiology, End Results (SEER) program. baseline...
To evaluate the feasibility, safety and efficacy of computed tomography (CT)-guided microcoil localization for small pulmonary lesions prior to thoracoscopic resection.We retrospectively reviewed medical data patients with solid nodules ground-glass opacity (GGO) who underwent CT-guided surgery. The was deployed proximal end coiling beyond parietal pleura while distal part anchoring in lung parenchyma. After marking microcoil, were removed by surgery.CT-guided placements successful all 98...
Thymic cysts are rare benign developmental anomalies and there is no consensus management for thymic cysts. The aim of this study was to disclose the efficacy perioperative diagnosis by chest computerized tomography (CT) elucidate surgical procedure video-assisted thoracic surgery (VATS) in cysts.We retrospectively reviewed 108 consecutive cyst patients who underwent VATS at our institution between April 2001 August 2015. All received CT preoperatively treatment. Clinical characteristics,...
Abstract Background To evaluate the surgical effect and prognostic factors of extended thymectomy for myasthenia gravis (MG) patients with thymomas. Methods Patients MG thymomas who underwent at Peking University People's Hospital Beijing between January 2010 December 2018 were retrospectively enrolled. followed up by telephone or outpatient record review . Statistical analyses performed using SPSS version 19.0. Results A total 194 included in this study. According to Osserman...