A5100407663- Pharmacological Effects of Natural Compounds
- Plant-based Medicinal Research
- Traditional Chinese Medicine Analysis
- Acute Kidney Injury Research
- Parathyroid Disorders and Treatments
- Diet and metabolism studies
- Tryptophan and brain disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Cancer, Hypoxia, and Metabolism
- Cancer-related molecular mechanisms research
- Anesthesia and Neurotoxicity Research
- Intestinal Malrotation and Obstruction Disorders
- T-cell and Retrovirus Studies
- Aortic aneurysm repair treatments
- Cancer, Stress, Anesthesia, and Immune Response
- Phytoestrogen effects and research
- Bone and Dental Protein Studies
- Potassium and Related Disorders
- Cancer Research and Treatments
- Medical Research and Treatments
- Inflammation biomarkers and pathways
- Chromatography in Natural Products
- Muscle and Compartmental Disorders
- Ginseng Biological Effects and Applications
- Asthma and respiratory diseases
Guangzhou Medical University
2016-2025
Peking Union Medical College Hospital
2022-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2023
Jilin Agricultural University
2023
University of Hong Kong
2023
University of Hong Kong - Shenzhen Hospital
2023
Capital Medical University
2023
Central South University
2013-2021
Second Xiangya Hospital of Central South University
2016-2021
Shandong Provincial Hospital
2020
Background Previous studies have shown that the gut microbiome is associated with thyroid diseases, including Graves' disease, Hashimoto's nodules, and cancer. However, association between intestinal flora primary hypothyroidism remains elusive. We aimed to characterize in patients. Methods Fifty-two patients 40 healthy controls were recruited. The differences microbiota two groups analyzed by 16S rRNA sequencing technology. Fecal transplantation (FMT) was performed mice using from both...
Oxidative stress and apoptosis play a key role in the pathogenesis of sepsis-associated acute kidney injury (AKI). Dexmedetomidine (DEX) may present renal protective effects sepsis. Therefore, we studied antioxidant mechanism DEX an inflammatory proximal tubular epithelial cell model lipopolysaccharide- (LPS-) induced AKI mice. Methods. We assessed function (creatinine, urea nitrogen), histopathology, oxidative (malondialdehyde (MDA) superoxide dismutase (SOD)), (TUNEL staining Cleaved...
Abstract Background Ultrasound is more widely used than mammography for early diagnosis of breast cancer in China as most Chinese women have small and dense mammary glands. This study compared the diagnostic performance ultrasound among with suspected lesions. Methods From November 2019 to 2021, we results lesion 2737 consecutive participants lesions; all patients underwent biopsies. We measured sensitivity, specificity, accuracy separately. Results Among participants, 2844 lesions were...
Abstract Background/Purpose Fetal hilar cyst is primarily diagnosed as two diseases after birth, cystic biliary atresia (CBA) and choledochal (CC). The aim of our study was to explore more reliable indicators in early differential diagnosis these cysts. Methods We recruited a total 50 cases with prenatal hepatic at three centers, patients were divided into CBA group ( n = 16) CC 34) according postnatal intraoperative diagnosis. Patient features, maximal diameter measured by ultrasonography...
To observe the effect of tribulus terrestris saponins (TTS) on behavior and neuroendocrine chronic mild stress (CMS) depression rats.Thirty male Sprague-Dawley rats were randomly allocated to six groups: vehicle group, CMS + fluoxetine group TTS low-dosage (0.375 g/kg), medium-dosage (0.75 g/kg) high-dosage (2.25 groups. All except singly housed exposed an unpredicted sequence stressors. The was detected by open-field test (OFT) sucrose preference (SPT). concentration corticotropin-releasing...
The steatotic grafts have been applied in liver transplantation frequently owing to the high incidence of non-alcoholic fatty disease. However, livers are vulnerable graft injury. Myeloid-derived suppressor cell (MDSC) recruitment during injury promotes tumour recurrence. Lipid metabolism exerts immunological influence on MDSCs progression. Here, we aimed explore role and mechanism inflammasome activation induced by lipid subsequent effects recurrence.MDSC populations nucleotide-binding...
The present study is aimed at examining the serum levels of brain-derived neurotrophic factor (BDNF) and investigating its role in differential diagnosis colorectal cancer (CRC). Materials Methods. In a Chinese population, we conducted case-control to compare diagnostic performance BDNF carcinoembryonic antigen (CEA) for CRC. We enrolled 61 healthy controls, 31 patients with adenomas, 81 explored correlation between several pathological features, such as tumor differentiation TNM staging....
Introduction Flaxseed oil (FO) and vitamin E (VE) both have antioxidant effects on sperm. The present study investigated the of dietary supplementation with FO and/or VE semen quality. Methods 16 fertile Simmental bulls were selected randomly divided into 4 groups (n = 4): control group (control diet), diet containing 24 g/kg FO), 150 mg/kg VE) FOVE trial lasted 10 weeks. Results results showed that addition independently can increase sperm motion parameters, levels catalase (CAT),...
<b><i>Background:</i></b> Extranodal natural killer (NK)/T cell lymphoma (ENKTL) is an aggressive non-Hodgkin's with high mortality and poor prognosis despite radiotherapy chemotherapy. The current analysis aimed to assess the pathological features, clinical prognostic indicators of ENKTL. <b><i>Material Methods:</i></b> 120 ENKTL patients were analyzed for pathologic diagnosis disease manifestations from April 2007 October 2012. Complete...
Abstract Background Chronic kidney disease (CKD) is associated with an increased cardiovascular (CVD) mortality risk. Elevation of cardiac biomarkers in patients renal dysfunction ambiguous the diagnosis CVD. The purpose this study was to investigate associations between estimated glomerular filtration rate (eGFR) and biomarkers, influence on biomarkers. Methods We examined cross‐sectional eGFR troponin I (cTnI), creatine kinase (CK), CK‐MB, lactic dehydrogenase (LDH), hydroxybutyrate...
Introduction Breast cancer is the most prevalent malignancy in patients with coronavirus disease 2019 (COVID-19). However, vaccination data of this population are limited. Methods A cross-sectional study COVID-19 was conducted China. Multivariate logistic regression models were used to assess factors associated status. Results Of 2,904 participants, 50.2% vaccinated acceptable side effects. Most participants received inactivated virus vaccines. The common reason for “fear infection” (56.2%)...
<b><i>Background:</i></b> Intraarterial injection into the hepatic artery represents an important route for locoregional administration treatment of tumors. In present work, we describe microsurgical methodology in mice. The technique was recently used analysis phenomenon endothelial capture liver <b><i>Methods:</i></b> Two different models tumors C57BL/6 mice were used. Tumors induced by intrahepatic cell inoculation. preferential blood supply...