A5010752845- Chronic Obstructive Pulmonary Disease (COPD) Research
- Trauma and Emergency Care Studies
- Emergency and Acute Care Studies
- Glioma Diagnosis and Treatment
- Childhood Cancer Survivors' Quality of Life
- Geriatric Care and Nursing Homes
- Healthcare Policy and Management
- Schizophrenia research and treatment
- Vasculitis and related conditions
- Respiratory Support and Mechanisms
- Dementia and Cognitive Impairment Research
- Acute Ischemic Stroke Management
- Systemic Sclerosis and Related Diseases
- Renal Diseases and Glomerulopathies
- Health Systems, Economic Evaluations, Quality of Life
- Heart Failure Treatment and Management
- Acute Lymphoblastic Leukemia research
- Frailty in Older Adults
- Primary Care and Health Outcomes
- Neurofibromatosis and Schwannoma Cases
- Chronic Disease Management Strategies
- Chemotherapy-induced cardiotoxicity and mitigation
- Global Health Care Issues
- Healthcare cost, quality, practices
- Clinical practice guidelines implementation
University of Toronto
2023-2024
Institute for Clinical Evaluative Sciences
2017-2024
Toronto Public Health
2019-2023
RELX Group (United States)
2023
Victor (Japan)
2023
University Health Network
2023
Policy Analysis (United States)
2019
Impact
2019
McMaster University
2019
International Council for the Exploration of the Sea
2019
Background and Purpose: We evaluated the influence of age on association between sex incidence stroke or transient ischemic attack (TIA) using a population-based cohort from Ontario, Canada. Methods: followed adults (≥18 years) without prior January 1, 2003 (cohort start date) to March 31, 2018, identify incident events. calculated hazard ratios (HRs), in women compared men, TIA, adjusted for demographics comorbidities, overall stratified by type. piecewise HRs each decade evaluate effect...
Peripartum mood and anxiety disorders constitute the most frequent form of maternal morbidity in general population, but little is known about peripartum mental illness mothers with multiple sclerosis (MS). We compared incidence prevalence among MS, epilepsy, inflammatory bowel disease (IBD), diabetes women without these conditions. Using linked population-based administrative health data from ON, Canada, we conducted a cohort study IBD, diseases (comparators) who had live birth index dates,...
Introduction The aim of our study was to assess the initial impact COVID-19 on total publicly-funded direct healthcare costs and health services use in two Canadian provinces, Ontario British Columbia (BC). Methods This retrospective repeated cross-sectional used population-based administrative datasets, linked within each province, from January 1, 2018 December 27, 2020. Interrupted time series analysis estimate changes level trends weekly resource costs, with March 16–22, 2020 as first...
Survivors of childhood medulloblastoma suffer from substantial late effects. We characterized these sequelae using real-world health services data in a population-based cohort survivors.
BACKGROUND Older adults who survive injury frequently experience functional decline, and interventions preventing this decline are needed. We therefore evaluated the association between early primary care physician (PCP) follow-up nursing home admission or death among injured older adults. METHODS performed a retrospective, population-based cohort study of community-dwelling (65 years older) discharged alive after injury-related hospitalization (2009–2020). The exposure interest was PCP...
BackgroundNearly half of patients transferred from non-trauma to trauma centres have minor injuries. The transfer with injuries is not associated any known patient benefit and represents an opportunity reduce healthcare costs improve experience. In this study, we evaluated the relationship between hospital resources overtriage, objective identifying targets for system-level intervention.MethodsWe conducted a population-based cohort study adults, age ≥ 16, presenting in Ontario, Canada...
Objective: Although evidence suggests that treatment seeking for mental illness has increased over time, little is known about how the health system meeting increasing demand services. We examined trends in physician-based service use across multiple sectors. Method: In this population-based study, we used linked health-administrative databases to measure annual rates of health–related outpatient physician visits family physicians and psychiatrists, emergency department visits,...
To estimate trends in the incidence and prevalence of GCA over time Canada.We performed a population-based study Ontario health administrative data using validated case definitions for GCA. Among residents ≥50 years age we estimated annual rates between 2000 2018. We sensitivity analyses alternative to provide comparative estimates.Between 2018 there was relatively stable with 25 new cases per 100 000 people >50 age. Age-standardized were significantly higher among females than males [31...
Nearly half the patients transferred from nontrauma centers to trauma have minor injuries, yet center care is not associated with a difference in morality among injuries. Consequently, reducing frequency of such transfers has been postulated as method improve resource allocation. Currently, economic implications these are well understood.
Background: Multiple sclerosis (MS) has been associated with certain comorbidities in general population studies, but it is unknown how comorbidity may affect immigrants MS. Objective: To compare prevalence of and long-term residents at MS diagnosis, matched control populations without Methods: We identified incident cases using a validated definition applied to health administrative data Ontario, Canada, from 1994 2017, categorized them as or residents. Immigrants (controls) were 3:1 on...
Introduction Respiratory-related morbidity and mortality were evaluated in relation to incident prescription oral synthetic cannabinoid (nabilone, dronabinol) use among older adults with chronic obstructive pulmonary disease (COPD). Methods This was a retrospective, population-based, data-linkage cohort study, analysing health administrative data from Ontario, Canada, 2006 2016. We identified individuals aged 66 years COPD, using highly specific, validated algorithm, excluding malignancy...
Objectives To describe healthcare use and spending before on becoming a new (incident) senior high-cost user (HCU) compared with non-HCUs; to estimate the incremental costs, overall by service category, attributable HCU status; quantify its monetary impact provincial budget in Ontario, Canada. Design We conducted retrospective, population-based comparative cohort study using administrative records. Incremental utilisation costs were determined method of recycled predictions allowing...
BACKGROUND The identification of patients who require transfer from non–trauma centers to trauma (secondary triage) is complicated by high rates undertriage and overtriage. objective this study was evaluate variations in secondary triage accuracy across identify factors associated with highly accurate triage. METHODS We performed a population-based injured presented large regional system. Patients were categorized as undertriaged, overtriaged, or appropriately triaged based on status...
Upper extremity (UE) trauma represents a common reason for emergency department visits, but the longitudinal economic burden of this public health issue is unknown. This study assessed 3-year attributable care use and expenditure after UE requiring acute surgical intervention, with specific focus on injuries that affect function hand wrist.We conducted an incidence-based, propensity score-matched cohort (2006-2014) in Ontario, Canada, using linked administrative data to identify case...
Background: Potentially inappropriate antipsychotic use has declined in nursing homes over the past decade; however, increases documentation of relevant clinical indications (eg, delusions) and other psychotropic medications have raised concerns about diagnosis upcoding medication substitution. Few studies examined how these trends time vary across within homes, information that may help to support reduction efforts. Objective: To jointly model facility-level potentially use, antidepressant...
Most health care spending is concentrated within a small group of high-cost users. To inform policies, we examined the characteristics index hospital admissions and their predictors among incident older users compared to non-high-cost in Ontario.Using Ontario administrative data, identified aged 66 years or more matched them 1:3 on age, gender Local Health Integration Network with more. We defined as patients top 5% most costly during fiscal year 2013/14 but not 2012/13. An admission, main...
Senior high-cost users (HCUs) are estimated to represent 60% of all HCUs in Ontario, Canada's most populous province. To improve our understanding individual and health system characteristics related senior HCUs, we will examine incident determine their incremental healthcare utilisation costs, index hospitalisation episodes, mortality regional variation across Ontario.A retrospective, population-based cohort study using administrative records be used. Incident defined as Ontarians aged ≥66...
Rationale: Although opioids are frequently prescribed in chronic obstructive pulmonary disease (COPD), there is poor understanding regarding which individuals will experience harm upon exposure.Objectives: We sought to identify patient characteristics and opioid drug properties predictive of opioid-related adverse events among older adults with COPD.Methods: A retrospective, population-based, cohort study design was used, analyzing Ontario heath administrative data. Individuals aged 66 years...
Reports of mortality risks among individuals with giant cell arteritis (GCA) have been mixed. Our aim was to evaluate all-cause GCA relative the general population over time.We performed a population-based study in Ontario, Canada using health administrative data. We studied cohort 22,677 patients ages ≥50 years that identified validated case definition (with 81% positive predictive value, 100% specificity). General comparators were residents without GCA. Deaths ascertained from vital...