A5062029974- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Vascular Malformations Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- MRI in cancer diagnosis
- Fetal and Pediatric Neurological Disorders
- Meningioma and schwannoma management
- Functional Brain Connectivity Studies
- Cerebral Venous Sinus Thrombosis
- Cerebrospinal fluid and hydrocephalus
- Glioma Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Cerebrovascular and Carotid Artery Diseases
- Salivary Gland Tumors Diagnosis and Treatment
- Viral Infections and Immunology Research
- Pneumonia and Respiratory Infections
- Peripheral Neuropathies and Disorders
- Liver Disease and Transplantation
- Medical Imaging Techniques and Applications
- Radiation Dose and Imaging
- Spinal Dysraphism and Malformations
- Hepatocellular Carcinoma Treatment and Prognosis
- Head and Neck Cancer Studies
- Neurofibromatosis and Schwannoma Cases
- Parkinson's Disease Mechanisms and Treatments
Jichi Medical University
2020-2025
Jichi Medical University Hospital
2021-2025
The University of Tokyo
2013-2024
Children's Medical Center
2023-2024
University of California, San Francisco
2010-2024
Hamamatsu University School of Medicine
2024
Tokyo Women's Medical University Yachiyo Medical Center
2024
Tokyo Women's Medical University
2024
San Francisco VA Medical Center
2024
University of Tokyo Hospital
2010-2023
We report the results of pathologic and biochemical studies in a patient with 6q-linked autosomal recessive juvenile parkinsonism (AR-JP). Neuronal loss gliosis were restricted to substantia nigra locus ceruleus. No Lewy bodies found, but neurofibrillary tangles argyrophilic astrocytes seen cerebral cortex brainstem nuclei. The later findings, which have not been reported previously AR-JP, suggest heterogeneity AR-JP.
In order to ensure that three-dimensional diffusion tensor tractography (3D-DTT) of the corticospinal tract (CST), is performed accurately and efficiently, we set out find optimal lower threshold fractional anisotropy (FA) below which elongation terminated (trackability threshold).Thirteen patients with acute or early subacute ischemic stroke causing motor deficits were enrolled in this study. We 3D-DTT CST MR (magnetic resonance) imaging. segmented established a cross-section transaxial...
IgG4-related disease is characterized by histologic fibrosis with IgG4-positive plasma cell infiltration. Our study evaluated MR imaging features of in the head and neck brain. Images from 15 patients were retrospectively for location, signal intensity, enhancement patterns lesions. Lacrimal gland enlargement was observed 8 cases. Other lesions included orbital pseudotumor 5, pituitary cranial nerve 7; infraorbital involved 4. All hypointense on T2-weighted images, which typical Multiple...
Acute flaccid myelitis (AFM) is an acute paralysis syndrome with spinal motor neuron involvement of unknown etiology. We investigated the characteristics and prognostic factors AFM clusters coincident enterovirus D68 (EV-D68) outbreak in Japan during autumn 2015.
Objective: To evaluate the crossing fiber trajectory through corpus callosum using distortion-corrected diffusion tensor tractography in human brain. Methods: After correcting distortion associated with large-diffusion gradients, T2-weighted echo planar images (EPIs) acquired from 10 right-handed healthy men were coregistered into fast spin linear sixth-order nonlinear, 3-dimensional, polynomial warping functions. The optimal transformation parameters also applied to diffusion-weighted EPIs....
Abstract The purpose of this study is to investigate whether the diffusional anisotropy water molecules disrupted in pyramidal and extra‐pyramidal regions patients with amyotrophic lateral sclerosis (ALS). We studied seven probable ALS (four women, mean age ± SD, 57.3 6.2 years old) according criteria World Federation Neurology. A control group consisted 11 age‐ sex‐matched volunteers (six 57.1 4.5) without disorders affecting central nervous system. Voxel‐based diffusion tensor analysis was...
Intrahepatic portosystemic venous shunt: occurrence in patients with and without liver cirrhosisH Mori, K Hayashi, T Fukuda, N Matsunaga, S Futagawa, M Nagasaki MutsukuraAudio Available | Share
In this study, the authors used preoperative simulation employing 3D computer graphics (interactive graphics) to fuse all imaging data for brainstem cavernous malformations. The evaluated whether interactive or 2D correlated better with actual operative field, particularly in identifying a developmental venous anomaly (DVA).The study population consisted of 10 patients scheduled surgical treatment Data from (MRI, CT, and rotational angiography) were automatically fused using normalized...
The aim of this study was to evaluate the anatomy and normal variations in craniocervical junction veins. We retrospectively reviewed 50 patients who underwent contrast-enhanced CT with a multidetector scanner. Axial reconstructed images were evaluated by two neuroradiologists special attention being paid existence size veins their relationships other venous branches around junction. structures contributing drainage, including inferior petrosal sinus (IPS), transverse-sigmoid sinus, jugular...
To elucidate differences between glioblastoma (GBM) and primary central nervous system lymphoma (PCNSL) with MR image-based texture features.This was an Institutional Review Board (IRB)-approved retrospective study. Consecutive, pathologically proven, initially treated 44 patients GBM 16 PCNSL were enrolled. We calculated a total of 67 image features on the largest contrast-enhancing lesion in each patient post-contrast T1-weighted images. Texture analyses included first-order (histogram)...
Approximately 5% of cerebral small vessel diseases are hereditary, which include COL4A1/COL4A2-related disorders. COL4A1/COL4A2 encode type IV collagen α1/2 chains in the basement membranes vessels. mutations impair secretion to extracellular matrix, thereby resulting fragility. The diagnostic yield for variants is around 20 30%, suggesting other mutated genes might be associated with this disease. This study aimed identify novel that cause disorders.Whole exome sequencing was performed 2...
Radiation therapy (RT) continues to play a central role as an effective therapeutic modality for variety of tumors and vascular malformations in the nervous system. Although planning delivery techniques RT have evolved substantially during past few decades, structures surrounding target lesion are inevitably exposed radiation. A wide radiation-induced changes may be observed at posttreatment imaging, which confusing when interpreting images. Histopathologically, radiation can deleterious...
Hypophysitis is one of the well-known adverse effects immune checkpoint inhibitors. Immune inhibitor-induced hypophysitis frequently causes irreversible hypopituitarism, which requires long-term hormone replacement. Despite high frequency and clinical significance, characteristic MR imaging findings have not been established. In present study, we aimed to review extract features hypophysitis.This retrospective international multicenter study comprised 20 patients with melanoma who were being...
MR imaging findings of LYH and pituitary adenomas are similar, but the therapeutic strategies completely different. The purpose this study was to evaluate sellar parasellar in patients with both diseases, as well characteristic clinical findings.Clinical findings, including endocrinologic images 20 22 adenoma, were retrospectively reviewed. We evaluated relation following: 1) PPHI on T1-weighted images, 2) thickened stalk (>3.5 mm), 3) symmetry, 4) enhancement pattern, 5) a dural tail, 6)...
The aim of this study was to evaluate the normal anatomy thoracic duct and cisterna chyli obtained by axial multiplanar reformation (MPR) images 1 mm slice thickness using multidetector row CT (MDCT).We evaluated ability MDCT examine chyli. coronal thoracoabdominal in 50 patients (20 females 30 males; mean age, 63.5 years; range, 32-81 years) were reviewed between January October 2005. We excluded with malignant neoplasms, inflammation or vascular diseases (e.g. aortic aneurysm, dissection)...
Background and Purpose: We analyzed the ability of a machine learning approach that uses diffusion tensor imaging (DTI) structural connectomes to determine lateralization epileptogenicity in temporal lobe epilepsy (TLE).Materials Methods: 3-dimensional (3D) T1-weighted images 44 patients with TLE (right, 15, left, 29; mean age, 33.0 ± 11.6 years) 14 age-matched controls. constructed whole brain connectome for each subject, calculated graph theoretical network measures, used support vector...
The symptoms of idiopathic normal pressure hydrocephalus (iNPH) can be improved by shunt surgery, but prediction treatment outcome is not established. We investigated changes the corticospinal tract (CST) in iNPH before and after surgery using diffusion microstructural imaging, which infers more specific tissue properties than conventional tensor imaging. Two biophysical models were used: neurite orientation dispersion density imaging (NODDI) white matter integrity (WMTI). In both methods,...
Although advanced MRI techniques are increasingly available, imaging differentiation between glioblastoma and primary central nervous system lymphoma (PCNSL) is sometimes confusing. We aimed to evaluate the performance of image classification by support vector machine, a method traditional machine learning, using texture features computed from contrast-enhanced T1-weighted images.This retrospective study on preoperative brain tumor included 76 consecutives, initially treated patients with (n...