A5017982198- Metabolism, Diabetes, and Cancer
- Diabetes and associated disorders
- Diabetes Treatment and Management
- Adipose Tissue and Metabolism
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Diabetes Management and Research
- Health and Wellbeing Research
- Pancreatic function and diabetes
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Thyroid Disorders and Treatments
- Dialysis and Renal Disease Management
- Cardiac Imaging and Diagnostics
- Cardiovascular Disease and Adiposity
- Blood Pressure and Hypertension Studies
- Pituitary Gland Disorders and Treatments
- Chronic Kidney Disease and Diabetes
- Apelin-related biomedical research
- Adrenal and Paraganglionic Tumors
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Alcohol Consumption and Health Effects
- BRCA gene mutations in cancer
- Sexual Differentiation and Disorders
- Neuroendocrine Tumor Research Advances
- Diabetes Management and Education
National Health Insurance Service
2009-2021
National Health Insurance Service Ilsan Hospital
2015-2021
Hallym University Sacred Heart Hospital
2020
Korea Advanced Institute of Science and Technology
2010
Yonsei University
2003-2004
The aim of this study was to estimate the prevalence and incidence type 1 diabetes mellitus (T1DM) in Korea. In addition, we planned do a performance analysis Registration Project Type for reimbursement consumable materials.To obtain nationwide data on T1DM, extracted claims from July 2011 August 2013 materials National Health Insurance (NHI) Database. For more detailed T1DM population Korea, stratification by gender, age, area performed, were calculated.Of 8,256 subjects enrolled over 26...
Metformin, the most widely used drug for type 2 diabetes, has recently attracted attention with regard to its antitumor activity. However, clinical studies have yielded conflicting results regarding association between metformin and thyroid cancer development, despite effect in preclinical studies.This is a retrospective cohort study using Korean National Health Insurance claim database. Matched populations of 128,453 users non-users were analyzed incidence. Metformin categorized into...
Epidemiological data is useful to estimate the necessary manpower and resources used for disease control prevention of prevalent chronic diseases. We aimed evaluate incidence diabetes identify its trends based on claims from National Health Insurance Service database over last decade.We extracted as principal first additional diagnoses January 2003 December 2012. investigated number newly claimed subjects with codes, demographic characteristics this population.Total numbers cases populations...
Dyslipidemia is a well-known risk factor for cardiovascular disease (CVD). Recently, atherogenic index of plasma (AIP) has been proposed as novel predictive marker CVD, and few cross sectional studies have demonstrated relationship between AIP coronary artery disease. The present study investigated the association progression calcification (CAC) in Korean adults without CVD. A total 1124 participants who had undergone CAC measurement at least twice by multi-detector computed tomography (CT)...
Abstract Boron neutron capture therapy (BNCT) has been attracting interest as a new radiation modality for cancer because it can selectively destroy cells while maintaining the healthy state of surrounding normal cells. Many experimental trials have demonstrated significant BNCT treatment efficacy using beams from research reactors. However, nuclear reactor technology cannot be scaled to sites in hospitals delivering patient treatment. Therefore, compact accelerator-based sources that could...
A direct association between low triiodothyronine (T3) syndrome and cardiovascular (CV) mortality has been reported in hemodialysis patients. However, the implications of this peritoneal dialysis (PD) patients have not properly investigated. This study examined T3 CV including sudden death a large cohort incident PD
Because of the development new classes antidiabetic drugs, hypoglycemic events were expected to decrease. We investigated trends and risk factors for severe hypoglycemia in subjects with type 2 diabetes Korea.We conducted repeated cross-sectional analyses using a Korean National Health Insurance Service-National Sample Cohort from 2006 2015. Severe was defined as hospitalization or visit an emergency department diagnosis ICD-10 codes.During study period, prevalence continuously increased....
To assess the efficacy and safety of gemigliptin, a dipeptidyl peptidase-4 inhibitor, added to metformin sulphonylurea in patients with type 2 diabetes (T2DM).We conducted randomized, double-blind, placebo-controlled trial 219 Korean inadequately controlled glimepiride. Participants were randomized gemigliptin 50 mg once daily or placebo The primary endpoint was change glycated haemoglobin (HbA1c) level from baseline week 24.The HbA1c 8.2% both groups. addition glimepiride significantly...
Diabet. Med. 27, 30–36 (2010) Abstract Aims We examined the effect of rosiglitazone on insulin sensitivity, abdominal fat and mid‐thigh intramuscular distribution, plasma concentrations adipocytokines in patients with Type 2 diabetes. Methods Rosiglitazone was administered at a daily dose 4 mg to 42 diabetes [age 32–70 years, body mass index (BMI) 17.5–32.6 kg/m , 15 women, 27 men] for 12 weeks. Various anthropometric metabolic profiles, adiponectin, leptin, resistin levels were measured,...
Hyperglycemia is associated with increased mortality and morbidity in patients type 2 diabetes mellitus (T2DM) who are undergoing dialysis. Although dipeptidyl peptidase-4 (DPP-4) inhibitors have been widely used end-stage renal disease (ESRD) T2DM, there few studies on their efficacy this population. We studied the effect of 3 different DPP-4 metabolic parameters ESRD T2DM. Two hundred T2DM were treated (sitagliptin, vildagliptin, or linagliptin) enrolled analyzed retrospectively. The...
Background: Hyperglycemic crisis is a metabolic emergency associated with diabetes mellitus.However, accurate epidemiologic information on cases of hyperglycemic in Korea remains scarce.We evaluated trends hospitalizations and in-and out-of-hospital mortality Korea.We also predicted future trends.Methods: We extracted claims data as the principal diagnosis from National Health Insurance Service database January 2004 to December 2013.We investigated numbers identified based those data.We by...
The volume of thyroid cancer screening and subsequent fine-needle aspiration (FNA) have rapidly increased in South Korea. We analyzed the diagnoses/thyroid FNA ratio according to annual number evaluate changes diagnostic efficiency FNA.This was a nationwide population-based retrospective cohort study. overall incremental diagnoses/incremental were indirectly calculated using data obtained from Korea Central Cancer Registry database Korean National Health Insurance Service claims 2004 2012....
Central obesity with visceral fat accumulation and the amount of skeletal muscle mass may influence insulin sensitivity via its capacity for glucose load uptake. We investigated relationships among following metabolic variables: ratio area to (VMR), percent ideal body weight, index, waist-to-hip circumference (WHR) subcutaneous (VSR) in 114 nondiabetic middle-aged women. Anthropometric parameters, lipid profiles sex hormone- binding globulin were measured. Visceral areas at umbilical level...
Research on the relationship between urinary albumin excretion and serum cystatin C in diabetes is restricted to cross-sectional studies. In this study, we investigated how well serial measurements of level reflect changes rate.We enrolled retrospectively collected data 1,058 participants with type 2 who were older than 18 years had more 3 follow-up albuminuria at an outpatient clinic.With use a linear mixed model, found that for each patient over time corresponded annual change C-based...
Klinefelter's syndrome is one of the most common forms primary hypogonadism and infertility in males. It characterized by small firm testes, gynecomastia, azoospermia, an elevated gonadotropin level. The frequencies diabetes mellitus, breast cancer, germ cell neoplasia increases syndrome. We report upon a 35 year-old male patient with Graves' disease association syndrome; as confirmed chromosome analysis. being treated antithyroid medication for testosterone replacement
Abstract Background Dyslipidemia is a well-known risk factor for cardiovascular disease (CVD). Recently, atherogenic index of plasma (AIP) has been proposed as novel predictive marker CVD, and there are few cross sectional studies that demonstrated relationship between AIP coronary artery disease. We investigated the association progression calcification (CAC) in Korean adults without CVD. Methods A total 1,124 participants who had undergone CAC measurement at least twice by multi-detector...
Since the discovery of perchlorate in water system, public has been concerned about its human health effect. In practice it was reported that chronic exposure to may lead damage thyroid hormone activity. This study introduced a method reduction, using autotrophic bacteria which utilise hydrogen as an electron donor. Two experiments were conducted compare effects acute and toxicity on bacterial reduction potential. One batch-fed operation generating another continuous-fed toxicity....
Background: Nonalcoholic fatty liver disease (NAFLD) is the most prevalent cause of chronic worldwide. Type 2 diabetes mellitus (T2DM) a risk factor that accelerates NAFLD progression, leading to fibrosis and cirrhosis. Thus, here we aimed develop simple model predict presence based on clinical parameters patients with T2DM.Methods: A total 698 T2DM who visited five medical centers were included. was evaluated using transient elastography. Univariate logistic regression analyses performed...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)