- Vasculitis and related conditions
- Atherosclerosis and Cardiovascular Diseases
- interferon and immune responses
- Nanoplatforms for cancer theranostics
- Immune Cell Function and Interaction
- Immune cells in cancer
- Cancer Immunotherapy and Biomarkers
- Renal Diseases and Glomerulopathies
- Extracellular vesicles in disease
- Phagocytosis and Immune Regulation
- Viral Infections and Vectors
- Immune Response and Inflammation
- Inflammasome and immune disorders
- demographic modeling and climate adaptation
- Vector-borne infectious diseases
- Pesticide Exposure and Toxicity
- Intraoperative Neuromonitoring and Anesthetic Effects
- Cancer, Hypoxia, and Metabolism
- Insurance, Mortality, Demography, Risk Management
- Maternal and Perinatal Health Interventions
- Economic and Financial Impacts of Cancer
- Acute Myocardial Infarction Research
- Malaria Research and Control
- Curcumin's Biomedical Applications
- Insect and Pesticide Research
First Hospital of Jilin University
2024
Jilin University
2024
Institute of High Energy Physics
2021-2024
Chinese Academy of Sciences
2021-2024
Sichuan University
2022-2024
West China Hospital of Sichuan University
2022-2024
First Bethune Hospital of Jilin University
2024
Shuguang Hospital
2023
Shanghai University of Traditional Chinese Medicine
2023
Anhui University of Traditional Chinese Medicine
2023
Recently Cairns et al. introduced a general framework for modeling the dynamics of mortality rates two related populations simultaneously. Their method ensures that resulting forecasts do not diverge over long run by difference in stochastic factors between with mean-reverting autoregressive process. In this article, we investigate how may be improved using vector error correction model. This extension is highly intuitive, allowing us to visualize cross-correlations and long-term equilibrium...
Background Scrub typhus, a serious public health problem in the Asia-Pacific area, is endemic "tsutsugamushi triangle" area. typhus has been widespread and become significant concern China. However, spatiotemporal patterns need to be investigated further. Objective This study aims explore patterns, diffusion characteristics regional distribution differences of scrub cases mainland China from January 2006 December 2017. Method Monthly reported at county level during 2006–2017 were obtained....
Abstract Radiated tumor cell‐derived extracellular vesicles (RT‐EVs) encapsulate abundant DNA fragments from irradiated cells, in addition to acting as integrators of multiple antigens. Accumulating evidence indicates these damaged cells are involved downstream immune responses, but most them degraded before incorporation into derived RT‐EVs, thus the low abundance limits responses RT‐EVs. Here, this study found that different radiations affected fates Boron neutron capture therapy (BNCT)...
To explore the clinical characteristics and etiology of bacterial meningitis (BM) in Chinese children.BM cases children 28days to 18 years old were collected from January 2014-December 2016 screened according World Health Organization standards. Clinical features, pathogens, resistance patterns analyzed.Overall, 837 classified into five age groups: 28 days-2 months (17.0%), 3-11 (27.8%), 12-35 (24.0%), 3-6 (13.9%), >6years (17.3%). Major pathogens Streptococcus pneumoniae (S. pneumoniae,...
The tumor-infiltrating immune cells are closely associated with the prognosis of gastric cancer (GC). This article is aimed at determining composition change and regulatory factors in GC normal tissues, depicting their value GC, revealing relationship between them clinical parameters.We used CIBERSORT to calculate proportion 22 or tissues; a t-test was applied assess expression difference tissues. cells, factors, patients' characteristics assessed by univariate analysis.In this study, we...
Precancerous lesions of gastric cancer (PLGC) refer to a kind histopathological changes in the mucosa that can progress cancer. Elian granules (ELG), Chinese medicinal prescription, have achieved satisfactory results treatment PLGC. However, exact mechanism underlying therapeutic effect ELG remains unclear. Here, this study aims explore alleviating PLGC rats.The chemical ingredients were analyzed using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS). Specific...
PURPOSE Mixed formulation of fosrolapitant and palonosetron (PALO), HR20013, is a novel fixed-dose intravenous antiemetic combination that could simultaneously antagonize neurokinin-1 5-hydroxytryptamine-3 receptors. This study was designed to evaluate the efficacy safety HR20013 plus dexamethasone (DEX) versus fosaprepitant (FAPR) PALO + DEX for preventing chemotherapy-induced nausea vomiting (CINV) in patients receiving highly emetogenic chemotherapy (HEC). METHODS noninferiority study....
Interferon-chi (IFN-χ) is a type of function-unknown IFN. IFN-χ in bovines (BoIFN-χ) has evolved as multigene family. This family comprises four subtypes, two which are functional genes, we demonstrated to (i) have antiviral and antiproliferative activities, (ii) be highly sensitive trypsin, (iii) remain stable with changes pH temperature. BoIFN-χ key intermediate response, PAbs against BoIFN-χs could downregulate the transcriptional activation ISGs induced by poly(I:C), upon virus infection...
Abstract Aim In patients with Takayasu's arteritis (TA), current biomarkers that properly reflect the progression of vascular structure remain absent. We aimed to determine serum leptin level investigate its relationship imaging changes and assess value as a predictor for long‐term radiological progression. Method This study included 34 untreated TA 40 age‐matched healthy controls. At baseline during 5‐year follow‐up, we assessed disease activity using Kerr's criteria Indian Takayasu...
Hypertension occurred in 30-80% of Takayasu arteritis (TAK) patients around the world and occurrence hypertension might worsen disease prognosis. This study aimed to investigate clinical characteristics imaging phenotypes, as well their associations with events free survival (EFS) Chinese TAK hypertension. current research was based on a prospectively ongoing observational cohort-the East China Arteritis (ECTA) cohort, centered Zhongshan Hospital, Fudan University. Totally, 204 were enrolled...
Cochineal red is an organic compound widely used in food, cosmetics, pharmaceuticals, textiles, and other fields due to its excellent safety profile. Poisoning caused by eating foods containing cochineal rare, repeated atrial arrhythmia poisoning even rarer.An 88-year-old Asian female patient was admitted hospital a disturbance of consciousness. Twelve hours prior presentation, the consumed 12 eggs over period 2 h. At coma had score 6 on Glasgow Coma Scale (E2 + VT M4). The patient's skin...
To elucidate the 3-year follow-up outcomes and risk factors associated with aortic regurgitation progression in Takayasu's arteritis (TAK).This study was a prospective cohort conducted among 77 patients TAK at Zhongshan Hospital, Fudan University, China. All participants were followed up assessed echocardiography for 3 years, baseline characteristics dynamic changes valve recorded investigated. A multivariable Cox model used to explore progression.The median onset age 36.9 (26.0-44.4) 57...