A5059511621- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Bone Tissue Engineering Materials
- Layered Double Hydroxides Synthesis and Applications
- Retinal Diseases and Treatments
- Ophthalmology and Visual Impairment Studies
- Orthopaedic implants and arthroplasty
- Ophthalmology and Eye Disorders
- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Advanced Drug Delivery Systems
- Synthesis and properties of polymers
- Retinal Imaging and Analysis
- Mesoporous Materials and Catalysis
- Electrospun Nanofibers in Biomedical Applications
- Intraocular Surgery and Lenses
- Bone health and treatments
- Clay minerals and soil interactions
- Bone fractures and treatments
- Therapeutic Uses of Natural Elements
- Inorganic Chemistry and Materials
- Drug Solubulity and Delivery Systems
- Complementary and Alternative Medicine Studies
- Sarcoma Diagnosis and Treatment
- Surgical Sutures and Adhesives
Seoul National University
2011-2020
Government of the Republic of Korea
2020
Ewha Womans University
2013-2019
University of Cambridge
2014
Samsung Medical Center
2010-2013
Sungkyunkwan University
2010-2013
Yonsei University
2010
To evaluate the long-term efficacy and rotational stability of AcrySof toric intraocular lens (IOL) in correcting preoperative astigmatism cataract patients.This prospective observational study included 30 eyes from 24 consecutive patients who underwent implantation an IOL with micro-coaxial surgery between May 2008 September 2008. Outcomes visual acuity, refractive keratometric astigmatism, rotation after 1 day, month, 3 months, (mean, 13.3+/-5.0 months) follow-up were evaluated.At final...
Diabetes may affect vascular autoregulation of the retina and optic nerve be associated with an increased risk glaucoma,but association prediabetes, insulin resistance, markers glucose metabolismwith glaucoma has not beenevaluated in general population samples.To examine relation between diabetes, pre-diabetes, metabolic syndrome its components levels fasting glucose, HbA1c HOMA-IR prevalence U.S. population.Cross-sectional study 3,299 adult men women from 2005-2008 National Health...
To estimate the heritabilities of myopia and ocular biometrics among different family types a Korean population.We studied 1508 adults in Healthy Twin Study. Spherical equivalent, axial length, anterior chamber depth, corneal astigmatism were measured by refraction, topography, A-scan ultrasonography. see degree resemblance relationships, intraclass correlation coefficients (ICC) calculated. Variance-component methods applied to genetic contributions eye phenotypes as heritability based on...
Intraocular pressure (IOP) reduction or stabilization is the only proven method for glaucoma management. Identifying risk factors IOP crucial to understand pathophysiology of glaucoma.To examine associations change in body mass index (BMI), waist circumference, and percent fat with intraocular a large sample Korean adults.Cohort study 274,064 young middle age adults normal fundoscopic findings who attended annual biennial health exams from January 1, 2002 Feb 28, 2010 (577,981 screening...
This study was conducted to compare endothelial cell (EC) loss, visual outcomes, and complications after deep anterior lamellar keratoplasty (DALK) penetrating (PK) in the contralateral eyes of same patients.A retrospective cohort undertaken at Samsung Medical Center, Seoul Korea. We reviewed records 8 patients (16 eyes) who underwent PK one eye DALK eye. The procedures were performed according Anwar Teichmann big-bubble technique. EC acuity, refractive status, evaluated these techniques.EC...
The purpose of this study was to analyze the relationship between age at menarche and myopia in Korean adult females.A total 8398 women least 19 years age, who participated National Health Nutrition Examination Survey from 2008 2012, underwent a refractive examination using an autorefractor. association severity evaluated four-level multinomial logistic regression analysis.The prevalence 61.77% (95% confidence interval [CI], 60.46-63.08), including 40.02% with low, 15.46% moderate, 6.29%...
A bioabsorbable polymeric bone plate enabled with both diagnostic and therapeutic functionalities (radiopacity sustained drug release, respectively) is proposed. To this end, a drug-inorganic nanohybrid (RS-LDH) examined as theranostic agent by intercalating an anti-resorptive remodeling drug, risedronate (RS) into layered double hydroxide (LDH) via ion-exchange reaction. The RS-LDH prepared sheet biodegradable polymer, poly(lactic-co-glycolic acid), then attached onto the clinically...
An attempt is made to describe an emerging convergence science: "nanomedicine". In particular, inorganic compounds such as anionic clays, layered double hydroxides (LDHs), at nanoscale, are underlined, with regard how they could interact bioactive and/or drug molecules form novel intercalative hybrid systems biocompatibility, imaging and targeting functions eventually for gene delivery. this regard, LDHs focused important biomaterial delivery carriers very high additive value in the near...
To examine the longitudinal association between age and intraocular pressure (IOP) in a large sample of Korean men women.We conducted prospective cohort study 274,064 young middle-aged adults with normal fundoscopic findings, following them from January 1, 2002, to February 28, 2010. Health exams were scheduled annually or biennially. At each visit, IOP was measured both eyes using automated noncontact tonometers. The change evaluated three-level mixed models for paired-eye data, accounting...
Ternary hybrids of brimonidine, montmorillonite and polyvinyl alcohol (BMD-MMT@PVA) can improve ocular drug bioavailability when administered topically to the eye.
To identify factors that influence near vision after monofocal intraocular lens (IOL) implantation for distance vision.A retrospective review was conducted of patients who underwent cataract surgery with IOL from October 2009 to April 2010 at Samsung Medical Center. Eyes were classified as having good (⩾ J4) or poor (< vision. Factors analyzed included age, sex, movement, axial length, pupil size, degree and type astigmatism, type, total aberration, higher-order aberrations. Binary logistic...
Abstract Bone fixation systems made of biodegradable polymers are radiolucent, making post‐operative diagnosis with X‐ray imaging a challenge. In this study, to allow visibility, we separately prepared radiopaque layer and attached it bioabsorbable bone plate approved for clinical use (Inion, Finland). We employed barium sulfate as material due the high attenuation coefficient (2.196 cm 2 /g). The was composed fine powder bound material, poly(lactic‐ co ‐glycolic acid) (PLGA), degradation...
Abstract Biodegradable polymer plates can be clinically used as an alternative to metal (e.g., titanium) for internal fixation, which, however, are not visible with X‐ray imaging, often post‐operative diagnostics. In this study, therefore, we prepared a biodegradable plate enabled visibility by attaching radiopaque layer on fixation in clinical use (Inion, Finland). A was made of fine powder agent, β‐tricalcium phosphate (TCP) and binder material, poly (lactic‐ co ‐glycolic acid) (PLGA),...
Background: Alendronate (AL), a drug for inhibiting osteoclast-mediated boneresorption, was intercalated into an inorganic delivery nanovehicle, layered double hydroxide (LDH), to form new nanohybrid, AL-LDH, with 1:1 heterostructure along the crystallographic C-axis.Based on intercalation reaction strategy, present AL-LDH system (DDS) realized enhanced efficacy of AL, which confirmed by improved proliferation and osteogenic differentiation osteoblast-like cells (MG63).Methods: The...