A5014192283- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Effects of Exercise
- Venous Thromboembolism Diagnosis and Management
- Heart Failure Treatment and Management
- Cardiac Valve Diseases and Treatments
- Congenital Heart Disease Studies
- Atrial Fibrillation Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Viral Infections and Immunology Research
- Cardiac Fibrosis and Remodeling
- Cardiac pacing and defibrillation studies
- Electrolyte and hormonal disorders
- Cardiovascular Health and Disease Prevention
- Cardiac and Coronary Surgery Techniques
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Arrhythmias and Treatments
- Cardiac Ischemia and Reperfusion
- Respiratory Support and Mechanisms
- Cardiomyopathy and Myosin Studies
- Adipokines, Inflammation, and Metabolic Diseases
Innsbruck Medical University
2013-2024
Universität Innsbruck
1999-2024
Newcastle upon Tyne Hospitals NHS Foundation Trust
2021
University Clinic of Traumatology
2014
MedStar Washington Hospital Center
2014
Aarhus University
2010-2013
Aarhus University Hospital
2011-2012
GTx (United States)
2011
University Hospital Innsbruck
1991-2002
Inserm
1999
The ESC Guidelines represent the views of and were produced after careful consideration scientific medical knowledge, evidence available at time their publication.The is not responsible in event any contradiction, discrepancy, and/or ambiguity between other official recommendations or guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies.Health professionals are encouraged take fully into account when exercising clinical...
Recommendations for the use of cardiac troponin (cTn) measurement in acute care have recently been published.1 Subsequently, a high-sensitivity (hs) cTn T assay was introduced into routine clinical practice.2 This assay, as others, called highly sensitive, permits concentrations significant numbers apparently illness-free individuals. These assays can measure single digit range nanograms per litre (=picograms millilitre) and some research even allow detection 10% at 99th percentile URL...
The release of cardiomyocyte components, i.e. biomarkers, into the bloodstream in higher than usual quantities indicates an ongoing pathological process. Thus, detection elevated concentrations cardiac biomarkers blood is a sign injury which could be due to supply–demand imbalance, toxic effects, or haemodynamic stress. It up clinician determine most probable aetiology, proper therapeutic measures, and subsequent risk implied by For this reason, measurement always must applied relation...
Abstract Background: The European Society of Cardiology/American College Cardiology Committee for the Redefinition Myocardial Infarction (MI) has recommended that an increased cardiac troponin should be defined as a measurement above 99th percentile value reference group. A total imprecision (CV) at decision limit ≤10% is recommended. However, peer-reviewed data on assay are lacking. purpose this study was to construct clinically relevant profiles each commercially available assays. Pools...
Cardiac troponins are often elevated in patients with skeletal muscle disease who have no evidence of cardiac disease. The goal this study was to characterize troponin concentrations myopathies and derive insights regarding the source T measurements. (cTnT) I (cTnI) were determined by using high sensitivity assays 74 hereditary acquired myopathies. Patients underwent comprehensive evaluation, including 12-lead electrocardiogram, 24-h magnetic resonance imaging, coronary artery computed...
Abstract Troponin T is a structurally bound protein found in striated muscle cells. We tested concentrations of its cardiac-specific isotype peripheral venous blood samples serially drawn from 72 patients with confirmed myocardial infarction. Fifty-nine received thrombolytic treatment intravenous streptokinase, urokinase, or recombinant tissue-type plasminogen activator; because contraindications, the remaining 13 did not. Concentrations troponin plasma, measured by an enzyme-linked...
High-sensitivity cardiac troponin assays enable measurement with a high degree of analytical sensitivity and low level imprecision at the measuring range. One most important advantages these new is that they allow novel, more rapid approaches for ruling in or out acute myocardial infarctions. The increase early diagnostic high-sensitivity comes cost reduced infarction specificity biomarker, because patients other causes chronic injury without overt ischaemia are detected than previous...
Cardiac troponin (cTn) T and cTnI are considered cardiac specific equivalent in the diagnosis of acute myocardial infarction. Previous studies suggested rare skeletal myopathies as a noncardiac source cTnT. We aimed to confirm reliability/cardiac specificity cTnT patients with various muscle disorders (SMDs).We prospectively enrolled presenting muscular complaints (≥2 weeks) for elective evaluation 4 hospitals 2 countries. After workup, were adjudicated into 3 predefined disease categories....
Abstract This paper presents evidence and suggestions from the IFCC Committee on “Standardization of Markers Cardiac Damage” (C-SMCD) use biochemical markers for triage diagnosis acute coronary syndromes. There is general agreement that both ‘early’ ‘definitive’ myocardial damage are necessary these assays must be available with a turnaround time 1 h or less. Currently, myoglobin marker most effectively fits role as an marker, whereas cardiac troponins. Since sensitivity initial...
In patients with acute ST-elevation myocardial infarction (STEMI), elevated concentrations of inflammatory markers are correlated worse clinical outcome. The aim this study was comprehensively to investigate the relationship circulating inflammation and microvascular damage after STEMI. 111 consecutive STEMI patients, blood samples were obtained on admission from day 1 4 primary percutaneous coronary intervention analysed for high-sensitivity C-reactive protein (hs-CRP), white cell count...